MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Rank	Network Comparison Type	description	Value Type	Interaction Map	red	green	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 25776 to 25824 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

Rank	Network Comparison Type	description	Value Type	red	green	network_comparison
3222	Subtracted	aldehyde dehydrogenase 7 (ec 1.2.1.5). [swissprot;acc:p43353]	Rooted	0	0	0
3223	Divided	ras-related protein ral-a. [swissprot;acc:p11233]	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
3224	Divided	integrin alpha-3 precursor (galactoprotein b3) (gapb3) (vla-3 alpha chain) (cd49c). [swissprot;acc:p26006]	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
3225	Divided	heat-shock 20 kda like-protein p20. [swissprot;acc:o14558]	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
3226	Divided	ccr4-not transcription complex, subunit 7 (ccr4-associated factor 1) (caf1) (btg1 binding factor 1). [swissprot;acc:q9uiv1]	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
3227	Divided	69 kda islet cell autoantigen (ica69) (islet cell autoantigen 1) (islet cell autoantigen p69) (icap69). [swissprot;acc:q05084]	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted
3228	Divided	ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]	Measured	0.00001	0.00001	1
			Ranked
			Squared
			Rooted
	Subtracted		Measured	0	0	0
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.