Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered Value Type Gene Network Comparison Type Rank Interaction Map description network_comparison green red
Results: HTML CSV LaTeX Showing element 51 to 100 of 77072 in total
Filtered  : 0
Value Type  : Measured
Network Comparison Type  : Divided
Rank
Interaction Map
description
network_comparison
green
red
26 High confidence fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402] 4.3268 662 153
Low confidence glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] 3.04255 47 143
27 High confidence phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [swissprot;acc:p11086] 4.10072 139 570
Low confidence melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] 2.97183 35.5 105.5
28 High confidence beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938] 4.10072 139 570
Low confidence melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357] 2.97183 35.5 105.5
29 High confidence potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281] 3.90833 434.911 111.278
Low confidence melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364] 2.97183 35.5 105.5
30 High confidence dystrophin. [swissprot;acc:p11532] 3.82335 111.739 427.217
Low confidence melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] 2.97183 35.5 105.5
31 High confidence dok-like protein. [refseq;acc:nm_024872] 3500000 0.00001 35
Low confidence hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] 2.97183 35.5 105.5
32 High confidence cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336] 3.25 184 598
Low confidence melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] 2.97183 35.5 105.5
33 High confidence lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [refseq;acc:nm_003893] 3.15402 39.8063 12.6208
Low confidence melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] 2.97183 35.5 105.5
34 High confidence glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] 3.04255 47 143
Low confidence melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] 2.97183 35.5 105.5
35 High confidence adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236] 2.99674 1377 459.5
Low confidence melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] 2.97183 35.5 105.5
36 High confidence heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174] 2.80357 56 157
Low confidence melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] 2.97183 35.5 105.5
37 High confidence 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 2.79409 934.348 334.401
Low confidence melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361] 2.97183 35.5 105.5
38 High confidence zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623] 2.65727 120.429 320.012
Low confidence melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732] 2.97183 35.5 105.5
39 High confidence microtubule-associated protein, rp/eb family, member 2; t-cell activation protein, eb1 family; apc-binding protein eb1. [refseq;acc:nm_014268] 2.50878 192.295 482.426
Low confidence melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365] 2.97183 35.5 105.5
40 High confidence nanos (fragment). [sptrembl;acc:q8wy41] 2.49669 151 377
Low confidence melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355] 2.97183 35.5 105.5
41 High confidence nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718] 2.42481 645 266
Low confidence melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363] 2.97183 35.5 105.5
42 High confidence presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341] 2.36266 86.9525 205.439
Low confidence melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366] 2.97183 35.5 105.5
43 High confidence elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897] 2.2301 587.988 263.66
Low confidence melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1] 2.97183 35.5 105.5
44 High confidence acyl-coa dehydrogenase, short/branched chain specific, mitochondrial precursor (ec 1.3.99.-) (sbcad) (2-methyl branched chain acyl-coa dehydrogenase) (2-mebcad) (2-methylbutyryl-coenzyme a dehydrogenase) (2-methylbutyryl-coa dehydrogenase). [swissprot;acc:p45954] 2.16837 98.5074 45.4292
Low confidence neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531] 28600000 0.00001 286
45 High confidence tigger transposable element derived 6. [refseq;acc:nm_030953] 2.1673 438.605 202.374
Low confidence neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721] 28600000 0.00001 286
46 High confidence tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208] 2.16674 438.035 202.163
Low confidence ephrin type-b receptor 4 precursor (ec 2.7.1.112) (tyrosine-protein kinase receptor htk). [swissprot;acc:p54760] 2.79167 67 24
47 High confidence tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702] 2.16672 438.016 202.156
Low confidence tenascin-x precursor (tn-x) (hexabrachion-like). [swissprot;acc:p22105] 2.50526 776.89 310.103
48 High confidence deltex homolog 1; hdx-1. [refseq;acc:nm_004416] 2.15895 403.196 870.482
Low confidence pnas-129. [sptrembl;acc:q9bxv8] 2.42708 151.073 366.666
49 High confidence selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611] 2.09722 151 72
Low confidence nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718] 2.42481 645 266
50 High confidence transcription factor 4 (immunoglobulin transcription factor 2) (itf-2) (sl3-3 enhancer factor 2) (sef-2). [swissprot;acc:p15884] 2.09524 21 44
Low confidence latrophilin 2; lectomedin-1; latrophilin homolog 2 (cow). [refseq;acc:nm_012302] 2.36036 111 262

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/