MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	description	Value Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 975 to 1024 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	description	Value Type
2999	TAF4	transcription initiation factor tfiid 135 kda subunit (tafii-135) (tafii135) (tafii-130) (tafii130). [swissprot;acc:o00268]	Squared
			Rooted
3000	PXDN	myeloblast kiaa0230 (fragment). [sptrembl;acc:q92626]	Measured
			Ranked
			Squared
			Rooted
3001	NEDD8	ubiquitin-like protein nedd8. [swissprot;acc:q15843]	Measured
			Ranked
			Squared
			Rooted
3002	CCNT1	cyclin t1 (cyclin t) (cyct1). [swissprot;acc:o60563]	Measured
			Ranked
			Squared
			Rooted
3003	LRRC6	testis specific leucine rich repeat protein. [refseq;acc:nm_012472]	Measured
			Ranked
			Squared
			Rooted
3004	SNRPN	small nuclear ribonucleoprotein associated protein n (snrnp-n) (sm protein n) (sm-n) (smn) (sm-d) (tissue-specific splicing protein). [swissprot;acc:p14648]	Measured
			Ranked
			Squared
			Rooted
3005	NDUFA5	nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]	Measured
			Ranked
			Squared
			Rooted
3006	DGCR8	dgcr8 protein (digeorge syndrome critical region 8). [swissprot;acc:q8wyq5]	Measured
			Ranked
			Squared
			Rooted
3007	YEATS4	glioma-amplified sequence-41; numa binding protein 1. [refseq;acc:nm_006530]	Measured
			Ranked
			Squared
			Rooted
3008	NUP214	nuclear pore complex protein nup214 (nucleoporin nup214) (214 kda nucleoporin) (can protein). [swissprot;acc:p35658]	Measured
			Ranked
			Squared
			Rooted
3009	COX6B1	cytochrome c oxidase polypeptide vib (ec 1.9.3.1) (aed). [swissprot;acc:p14854]	Measured
			Ranked
			Squared
			Rooted
3010	UROD	uroporphyrinogen decarboxylase (ec 4.1.1.37) (uro-d) (upd). [swissprot;acc:p06132]	Measured
			Ranked
			Squared
			Rooted
3011	MCM8	dna replication licensing factor mcm8 (minichromosome maintenance 8). [swissprot;acc:q9uja3]	Measured
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.