Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Value Type Network Comparison Type red Rank description green Interaction Map Filtered network_comparison
Results: HTML CSV LaTeX Showing element 2175 to 2224 of 3228 in total
Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
red
Rank
description
green
network_comparison
5996.06 2504 succinyl-coa ligase [adp-forming] beta-chain, mitochondrial precursor (ec 6.2.1.5) (succinyl-coa synthetase, betaa chain) (scs-betaa) (atp- specific succinyl-coa synthetase beta subunit). [swissprot;acc:q9p2r7] 6155.81 1.02664
5996.14 1517 26s proteasome non-atpase regulatory subunit 9 (26s proteasome regulatory subunit p27). [swissprot;acc:o00233] 6439.46 1.07393
5997.24 1226 tyrosinase-related gene segment, exon 5 (fragment). [sptrembl;acc:q15677] 6508.62 1.08527
5998.58 1228 dopachrome tautomerase precursor (ec 5.3.3.12) (dt) (dct) (dopachrome delta-isomerase) (tyrosinase-related protein 2) (trp-2) (trp2). [swissprot;acc:p40126] 6509.65 1.0852
5998.69 1229 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (ec 1.14.18.-) (dhica oxidase) (tyrosinase-related protein 1) (trp-1) (trp1) (trp) (catalase b) (glycoprotein-75) (melanoma antigen gp75). [swissprot;acc:p17643] 6509.74 1.08519
6000.07 811 atp synthase delta chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p30049] 6655.11 1.10917
6000.23 728 hcv ns3-transactivated protein 1. [refseq;acc:nm_019048] 6696.89 1.11611
729 vacuolar atp synthase catalytic subunit a, ubiquitous isoform (ec 3.6.3.14) (v-atpase a subunit 1) (vacuolar proton pump alpha subunit 1) (v-atpase 69 kda subunit 1) (isoform va68). [swissprot;acc:p38606]
730 asparagine synthetase [glutamine-hydrolyzing] (ec 6.3.5.4) (glutamine- dependent asparagine synthetase) (ts11 cell cycle control protein). [swissprot;acc:p08243]
6001.16 1214 mitogen-activated protein kinase kinase kinase 7 (ec 2.7.1.-) (transforming growth factor-beta-activated kinase 1) (tgf-beta- activated kinase 1). [swissprot;acc:o43318] 6515.9 1.08577
6004.54 1233 tyrosinase precursor (ec 1.14.18.1) (monophenol monooxygenase) (tumor rejection antigen ab) (sk29-ab) (lb24-ab). [swissprot;acc:p14679] 6514.24 1.08489
6011.44 1223 transketolase-like 1 (ec 2.2.1.1) (transketolase 2) (tk 2) (transketolase related protein). [swissprot;acc:p51854] 6524.55 1.08536
6011.57 1751 60 kda tat interactive protein (tip60) (hiv-1 tat interactive protein) (cpla(2) interacting protein). [swissprot;acc:q92993] 6414.98 1.06711
6018.7 1557 vacuolar protein sorting 18 (hvps18). [swissprot;acc:q9p253] 6455.7 1.07261
6021.21 1217 cad protein [includes: glutamine-dependent carbamoyl-phosphate synthase (ec 6.3.5.5); aspartate carbamoyltransferase (ec 2.1.3.2); dihydroorotase (ec 3.5.2.3)]. [swissprot;acc:p27708] 6536.45 1.08557
6024.47 2097 polypeptide n-acetylgalactosaminyltransferase 2; udp-galnac transferase 2. [refseq;acc:nm_004481] 6356.56 1.05512
2098 similar to expressed sequence ai415388 (fragment). [sptrembl;acc:q8n428]
6025.86 1549 glucose-6-phosphate 1-dehydrogenase (ec 1.1.1.49) (g6pd). [swissprot;acc:p11413] 6464.16 1.07274
1550 dna-repair protein xrcc3 (x-ray repair cross-complementing protein 3). [swissprot;acc:o43542]
1552 atp-dependent dna helicase q5 (recq protein-like 5) (recq5). [swissprot;acc:o94762]
6035.6 1613 mitochondrial 28s ribosomal protein s22 (s22mt) (mrp-s22) (gk002). [swissprot;acc:p82650] 6464.5 1.07106
1614 nefa-interacting nuclear protein nip30. [refseq;acc:nm_024946]
1615 lim homeobox transcription factor 1 alpha (lim/homeobox protein lmx1a) (lim-homeobox protein 1.1) (lmx-1.1). [swissprot;acc:q8te12]
1616 mitochondrial precursor proteins import receptor (translocase of outer membrane tom70). [swissprot;acc:o94826]
1617 lim homeobox transcription factor 1 beta (lim/homeobox protein lmx1b) (lim-homeobox protein 1.2) (lmx-1.2). [swissprot;acc:o60663]
1618 proteasome subunit beta type 2 (ec 3.4.25.1) (proteasome component c7-i) (macropain subunit c7-i) (multicatalytic endopeptidase complex subunit c7-i). [swissprot;acc:p49721]
1619 adp-ribosylation factor-like protein 1. [swissprot;acc:p40616]
6036.22 1354 actin, cytoplasmic 2 (gamma-actin). [swissprot;acc:p02571] 6512.64 1.07893
6036.62 2042 kinesin light chain 2 (klc 2). [swissprot;acc:q9h0b6] 6379.38 1.05678
6036.68 2040 rho-gtpase-activating protein 8. [swissprot;acc:q9nsg0] 6379.44
2041 rho-gtpase-activating protein 1 (gtpase-activating protein rhoogap) (rho-related small gtpase protein activator) (cdc42 gtpase-activating protein) (p50-rhogap). [swissprot;acc:q07960]
2043 kinesin heavy chain (ubiquitous kinesin heavy chain) (ukhc). [swissprot;acc:p33176]
2044 kinesin heavy chain isoform 5c (kinesin heavy chain neuron-specific 2). [swissprot;acc:o60282]
2045 neuronal kinesin heavy chain (nkhc) (kinesin heavy chain isoform 5a) (kinesin heavy chain neuron-specific 1). [swissprot;acc:q12840]
2047 transcription factor iiia (factor a) (tfiiia). [swissprot;acc:q92664]
2048 exocyst complex component sec3 (bm-012). [swissprot;acc:q9nv70]
6036.73 2046 kinesin light chain 1 (klc 1). [swissprot;acc:q07866] 6379.48
6038.46 1627 6-phosphogluconolactonase (ec 3.1.1.31) (6pgl). [swissprot;acc:o95336] 6463.9 1.07046
6042.31 1201 thymidylate kinase (ec 2.7.4.9) (dtmp kinase). [swissprot;acc:p23919] 6565.03 1.08651
6042.36 2452 succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (ec 1.3.5.1) (fp) (flavoprotein subunit of complex ii). [swissprot;acc:p31040] 6237.19 1.03224
6048.57 1558 vacuolar protein sorting 33b (hvps33b). [swissprot;acc:q9h267] 6487.65 1.07259
1559 vacuolar protein sorting 11 (hvps11) (pp3476). [swissprot;acc:q9h270]
1560 vacuolar protein sorting 33a (hvps33a). [swissprot;acc:q96ax1]
6051.06 1725 glucose-6-phosphate isomerase (ec 5.3.1.9) (gpi) (phosphoglucose isomerase) (pgi) (phosphohexose isomerase) (phi) (neuroleukin) (nlk) (sperm antigen-36) (sa-36). [swissprot;acc:p06744] 6463.65 1.06818
6051.23 1310 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (tak1-binding protein 1). [swissprot;acc:q15750] 6544.17 1.08146
6057.46 1491 fidgetin-like 1. [refseq;acc:nm_022116] 6510.9 1.07486
6064.92 2005 atp-citrate synthase (ec 2.3.3.8) (atp-citrate (pro-s-)-lyase) (citrate cleavage enzyme). [swissprot;acc:p53396] 6421.65 1.05882
6066.61 2295 glutathione s-transferase p (ec 2.5.1.18) (gst class-pi) (gstp1-1). [swissprot;acc:p09211] 6344.65 1.04583
6068.03 1572 proteasome subunit alpha type 1 (ec 3.4.25.1) (proteasome component c2) (macropain subunit c2) (multicatalytic endopeptidase complex subunit c2) (proteasome nu chain) (30 kda prosomal protein) (pros-30). [swissprot;acc:p25786] 6504.59 1.07194
6069.65 1717 inositol-1(or 4)-monophosphatase (ec 3.1.3.25) (impase) (imp) (inositol monophosphatase) (lithium-sensitive myo-inositol monophosphatase a1). [swissprot;acc:p29218] 6484.94 1.06842

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/