MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Filtered	Gene	green	network_comparison	Network Comparison Type	Rank	red	Interaction Map	description

Results: HTML CSV LaTeX

Showing element 51 to 100 of 77072 in total

Value Type  : Measured
Filtered  : 0

green	network_comparison	Network Comparison Type	Rank	red	Interaction Map	description
0.00001	3700000	Divided	22	37	Low confidence	carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [refseq;acc:nm_021615]
			23			carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [refseq;acc:nm_004267]
	6000000		22	60	High confidence	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]
	8200000		20	82		ero1-like. [refseq;acc:nm_014584]
	15400000		95	154		nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
			96			transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	28600000		44	286	Low confidence	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]
			45			neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721]
	36400000		1	364	High confidence	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]
					Low confidence
5.56738	35.8425		10	199.549		serpin b12. [swissprot;acc:q96p63]
			11		High confidence
	193.982	Subtracted	168
			280		Low confidence
5.71669	34.8539	Divided	11	199.249		hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]
			12		High confidence
	193.532	Subtracted	169
			281		Low confidence
6.50325	20.0687	Divided	14	130.512	High confidence	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]
	124.009	Subtracted	258
10.6048	36.1876	Divided	9	383.762	Low confidence	ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
	373.157	Subtracted	166
11.5	1.21739	Divided	176	14		protocadherin 16 precursor (cadherin 19) (cadherin fibroblast 1). [swissprot;acc:q96jq0]
			190		High confidence
	2.5	Subtracted	489
			819		Low confidence
14.3333	1.3721	Divided	121	19.6667	High confidence	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]
	5.3334	Subtracted	460
15	14		443	1		protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]
	15	Divided	16
17.5166	17.5166	Subtracted	755	0	Low confidence	jumonji protein. [swissprot;acc:q92833]
	1751660	Divided	5	0.00001
17.6611	6.73106		21	118.878	High confidence	syntaxin 10 (syn10). [swissprot;acc:o60499]
	101.217	Subtracted	269
18	18		428	0		phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]
	1800000	Divided	64	0.00001
19	1.21053		184	23	Low confidence	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]
			195		High confidence
	4	Subtracted	464
			807		Low confidence
	5.21053	Divided	18	99		camp-regulated phosphoprotein 19 (arpp-19) [contains: camp-regulated phosphoprotein 16 (arpp-16)]. [swissprot;acc:p56211]
	80	Subtracted	483
21	2.09524	Divided	50	44	High confidence	transcription factor 4 (immunoglobulin transcription factor 2) (itf-2) (sl3-3 enhancer factor 2) (sef-2). [swissprot;acc:p15884]
	23	Subtracted	407
23.6984	2.03615	Divided	64	48.2534	Low confidence	dna helicase homolog (fragment). [sptrembl;acc:q9y645]
	24.555	Subtracted	713
26.1599	11.6763	Divided	18	305.45	High confidence	60s ribosomal protein l37a. [swissprot;acc:p12751]
			19			25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]
	279.29	Subtracted	114			60s ribosomal protein l37a. [swissprot;acc:p12751]
			115			25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.