Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank Value Type Network Comparison Type green Interaction Map description red network_comparison Filtered
Results: HTML CSV LaTeX Showing element 2051 to 2100 of 3228 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
Rank
green
description
red
network_comparison
2051 216.981 oxidation resistance 1. [refseq;acc:nm_181354] 218.79 1.00834
2052 205.95 ornithine decarboxylase antizyme inhibitor. [swissprot;acc:o14977] 207.667
2053 216.981 lats, large tumor suppressor, homolog 2; lats (large tumor suppressor, drosophila) homolog 2. [refseq;acc:nm_014572] 218.79
2054 205.948 ornithine decarboxylase-like protein (ec 4.1.1.17) (odc-paralogue) (odc-p). [swissprot;acc:q96a70] 207.665
2055 216.981 dymeclin. [refseq;acc:nm_017653] 218.79
2056 sh3 domain-binding glutamic acid-rich-like protein. [swissprot;acc:o75368]
2057 lats homolog 1. [refseq;acc:nm_004690]
2058 sh3 domain-binding glutamic acid-rich-like protein 2 (fovea-associated sh3 domain binding protein). [swissprot;acc:q9ujc5]
2059 nuclear receptor coactivator 7; estrogen receptor associated protein 140 kda. [refseq;acc:nm_181782]
2060 dj132f21.2 (contains a novel protein similar to the l82e from drosophila) (fragment). [sptrembl;acc:q9h125]
2061 tbc1 domain family protein c22orf4-like (fragment). [swissprot;acc:q9nu19]
2062 tbc1 domain family protein c22orf4. [swissprot;acc:q8wua7]
2063 205.923 ornithine decarboxylase (ec 4.1.1.17) (odc). [swissprot;acc:p11926] 207.638 1.00833
2064 205.939 aminoadipate-semialdehyde synthase; lysine-ketoglutarate reductase /saccharopine dehydrogenase; lysine-2-oxoglutarate reductase; aminoadipic semialdehyde synthase. [refseq;acc:nm_005763] 207.655
2065 212.561 ubiquitin-conjugating enzyme e2 n (ec 6.3.2.19) (ubiquitin-protein ligase n) (ubiquitin carrier protein n) (ubc13) (bendless-like ubiquitin conjugating enzyme). [swissprot;acc:q16781] 214.328 1.00831
2066 231.001 proliferating cell nuclear antigen (pcna) (cyclin). [swissprot;acc:p12004] 229.102 1.00829
2067 191.639 adenylosuccinate lyase (ec 4.3.2.2) (adenylosuccinase) (asl) (asase). [swissprot;acc:p30566] 193.226 1.00828
2068 222.61 fas apoptotic inhibitory molecule. [refseq;acc:nm_018147] 220.8 1.0082
2069 215.807 dual specificity mitogen-activated protein kinase kinase 1 (ec 2.7.1.-) (map kinase kinase 1) (mapkk 1) (erk activator kinase 1) (mapk/erk kinase 1) (mek1). [swissprot;acc:q02750] 217.555 1.0081
2070 225.008 rac gtpase activating protein 1; gtpase activating protein. [refseq;acc:nm_013277] 223.199
2071 215.807 similar to kinase suppressor of ras (fragment). [sptrembl;acc:q8ivt5] 217.555
2072 dual specificity mitogen-activated protein kinase kinase 2 (ec 2.7.1.-) (map kinase kinase 2) (mapkk 2) (erk activator kinase 2) (mapk/erk kinase 2) (mek2). [swissprot;acc:p36507]
2073 227.433 topoisomerase-related function protein 4-2. [refseq;acc:nm_022447] 229.267 1.00806
2074 214.599 dna polymerase gamma subunit 1 (ec 2.7.7.7) (mitochondrial dna polymerase catalytic subunit) (polg-alpha). [swissprot;acc:p54098] 216.324 1.00804
2075 223.483 cd109; gov system alloantigens on platelets. [refseq;acc:nm_133493] 221.703 1.00803
2076 peptidyl-prolyl cis-trans isomerase nima-interacting 1 (ec 5.2.1.8) (rotamase pin1) (ppiase pin1). [swissprot;acc:q13526]
2077 iroquois-class homeodomain protein irx-4 (iroquois homeobox protein 4). [swissprot;acc:p78413]
2078 213.814 fidgetin-like 1. [refseq;acc:nm_022116] 215.511 1.00794
2079 214.28 phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing gamma polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-gamma) (ptdins-3-kinase c2 gamma) (pi3k-c2gamma). [swissprot;acc:o75747] 215.967 1.00787
2080 phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]
2081 dynamin 1-like protein isoform 3; dynamin-like protein. [refseq;acc:nm_005690]
2082 phosphoinositide-3-kinase, class 2, alpha polypeptide; c2-containing phosphatidylinositol kinase. [refseq;acc:nm_002645]
2083 213.579 vacuolar protein sorting 16 (hvps16). [swissprot;acc:q9h269] 215.258 1.00786
2084 224.293 glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (ec 2.6.1.16) (hexosephosphate aminotransferase 1) (d-fructose-6- phosphate amidotransferase 1) (gfat 1) (gfat1). [swissprot;acc:q06210] 222.548 1.00784
2085 224.32 isocitrate dehydrogenase [nad] subunit alpha, mitochondrial precursor (ec 1.1.1.41) (isocitric dehydrogenase) (nad+-specific icdh). [swissprot;acc:p50213] 222.58 1.00782
2086 isocitrate dehydrogenase [nad] subunit beta, mitochondrial precursor (ec 1.1.1.41) (isocitric dehydrogenase) (nad+-specific icdh). [swissprot;acc:o43837]
2087 isocitrate dehydrogenase [nad] subunit gamma, mitochondrial precursor (ec 1.1.1.41) (isocitric dehydrogenase) (nad+-specific icdh). [swissprot;acc:p51553]
2088 216.433 maguk p55 subfamily member 3 (mpp3 protein) (discs, large homolog 3). [swissprot;acc:q13368] 218.124 1.00781
2089 213.479 serologically defined colon cancer antigen 16. [refseq;acc:nm_006649] 215.144 1.0078
2090 224.344 glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (ec 2.6.1.16) (hexosephosphate aminotransferase 2) (d-fructose-6- phosphate amidotransferase 2) (gfat 2) (gfat2). [swissprot;acc:o94808] 222.609 1.00779
2091 210.052 rna, u transporter 1; snurportin-1. [refseq;acc:nm_005701] 211.679 1.00775
2092 210.369 evolutionarily conserved signaling intermediate in toll pathway; ecsit. [refseq;acc:nm_016581] 211.992 1.00772
2093 208.387 ribokinase (ec 2.7.1.15). [swissprot;acc:q9h477] 209.994 1.00771
2094 205.747 pms1 protein homolog 2 (dna mismatch repair protein pms2). [swissprot;acc:p54278] 207.321 1.00765
2095 227.53 polymerase (dna directed) sigma; topoisomerase-related function protein 4-1; polymerase (dna-directed) sigma. [refseq;acc:nm_006999] 229.266 1.00763
2096 216.089 limkain beta 2. [refseq;acc:nm_025140] 217.723 1.00756
2097 213.39 delta-interacting protein a (hepatitis delta antigen interacting protein a). [swissprot;acc:q15834] 214.979 1.00745
2098 178.831 ret finger protein 2 (leukemia associated protein 5) (b-cell chronic lymphocytic leukemia tumor suppressor leu5) (putative tumor suppressor rfp2) (tripartite motif protein 13). [swissprot;acc:o60858] 177.515 1.00741
2099 213.27 ubiquitin-like protein smt3a. [swissprot;acc:p55854] 211.71 1.00737
2100 ubiquitin-like protein smt3b (sentrin 2) (hsmt3). [swissprot;acc:p55855]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/