Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene Value Type Network Comparison Type Rank network_comparison Interaction Map red description green Filtered

Results: HTML CSV LaTeX

Showing element 2051 to 2100 of 3228 in total

Value Type

: Measured
Network Comparison Type

: Divided
Interaction Map

: High confidence
Filtered

: 1

Rank	network_comparison	red	description	green
2051	1.05646	3601.97	60s ribosomal protein l26. [swissprot;acc:q02877]	3409.48
2052	1.05642	5634.8	polybromo 1. [refseq;acc:nm_018165]	5952.7
2053			swi/snf-related matrix-associated actin-dependent regulator of chromatin a5; sucrose nonfermenting-like 5. [refseq;acc:nm_003601]
2054			possible global transcription activator snf2l4 (snf2-beta) (brg-1 protein) (mitotic growth and transcription activator) (brahma protein homolog 1). [swissprot;acc:p51532]
2055			possible global transcription activator snf2l1. [swissprot;acc:p28370]
2056			tbp-associated factor 172 (taf-172) (taf(ii)170). [swissprot;acc:o14981]
2057			possible global transcription activator snf2l2 (snf2-alpha). [swissprot;acc:p51531]
2058	1.0564	5552.69	adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]	5865.84
2059			adapter-related protein complex 1 gamma 1 subunit (gamma-adaptin) (adaptor protein complex ap-1 gamma-1 subunit) (golgi adaptor ha1/ap1 adaptin gamma-1 subunit) (clathrin assembly protein complex 1 gamma-1 large chain). [swissprot;acc:o43747]
2060			adapter-related protein complex 1 sigma 1c subunit (sigma-adaptin 1c) (adaptor protein complex ap-1 sigma-1c subunit) (golgi adaptor ha1/ap1 adaptin sigma-1c subunit) (clathrin assembly protein complex 1 sigma- 1c small chain) (sigma 1c subunit of ap-1 clathrin). [swissprot;acc:q96pc3]
2061			adapter-related protein complex 1 sigma 1a subunit (sigma-adaptin 1a) (adaptor protein complex ap-1 sigma-1a subunit) (golgi adaptor ha1/ap1 adaptin sigma-1a subunit) (clathrin assembly protein complex 1 sigma- 1a small chain) (clathrin coat assembly protein ap19) (ha1 19 kda subunit) (sigma 1a subunit of ap-1 clathrin). [swissprot;acc:q00382]
2062		5552.7	adapter-related protein complex 1 gamma 2 subunit (gamma2-adaptin) (adaptor protein complex ap-1 gamma-2 subunit) (g2ad). [swissprot;acc:o75843]	5865.85
2063	1.05635	5634.63	swi/snf-related matrix-associated actin-dependent regulator of chromatin c1; mammalian chromatin remodeling complex brg1-associated factor 155; swi/snf complex 155 kda subunit; chromatin remodeling complex baf155 subunit. [refseq;acc:nm_003074]	5952.14
2064	1.05632	5548.79	adapter-related protein complex 1 beta 1 subunit (beta-adaptin 1) (adaptor protein complex ap-1 beta-1 subunit) (golgi adaptor ha1/ap1 adaptin beta subunit) (clathrin assembly protein complex 1 beta large chain). [swissprot;acc:q10567]	5861.31
2065	1.05631	3602.25	60s ribosomal protein l35. [swissprot;acc:p42766]	3410.23
2066	1.05622	5882.61	similar to glucosamine-phosphate n-acetyltransferase (hypothetical protein flj33258). [sptrembl;acc:q96ek6]	6213.34
2067	1.05616	3602.75	40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	3411.18
2068	1.05616	3602.75	mitochondrial ribosomal protein l2. [refseq;acc:nm_015950]	3411.17
2069	1.05613	4632.65	dna-directed rna polymerase i 16 kda polypeptide (ec 2.7.7.6) (rpa16). [swissprot;acc:q9y2s0]	4892.66
2070	1.05607	10178.5	splicing factor, proline-and glutamine-rich (polypyrimidine tract- binding protein-associated splicing factor) (ptb-associated splicing factor) (psf) (dna-binding p52/p100 complex, 100 kda subunit). [swissprot;acc:p23246]	9638.08
2071	1.05592	6437.24	28s ribosomal protein s26, mitochondrial precursor (mrp-s26) (mrp- s13). [swissprot;acc:q9byn8]	6797.24
2072	1.05592	6437.24	enhancer of rudimentary homolog. [swissprot;acc:q14259]	6797.24
2073	1.05585	6083.39	peptidylprolyl isomerase-like 4; cyclophilin-type peptidyl-prolyl cis-trans isomerase; ppiase; serologically defined breast cancer antigen ny-br-18. [refseq;acc:nm_139126]	6423.12
2074	1.05579	3614.91	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	3423.89
2075		3614.91	serine racemase (ec 5.1.1.-). [swissprot;acc:q9gzt4]	3423.89
2076		5746.65	af-6 protein. [swissprot;acc:p55196]	6067.27
2077		3614.91	60s ribosomal protein l34. [swissprot;acc:p49207]	3423.89
2078			protein transport protein sec61 alpha subunit isoform 2 (sec61 alpha- 2). [swissprot;acc:q9y2r3]
2079			protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378]
2080	1.05577	5837.34	r3h domain protein 1. [swissprot;acc:q15032]	6162.91
2081	1.05568	6318.3	paired box protein pax-6 (oculorhombin) (aniridia, type ii protein). [swissprot;acc:p26367]	6670.1
2082	1.05559	5800.93	ran-binding protein 2 (ranbp2) (nuclear pore complex protein nup358) (nucleoporin nup358) (358 kda nucleoporin) (p270). [swissprot;acc:p49792]	6123.38
2083	1.05558	5799.84	ran-binding protein 2-like 1 isoform 2; sperm membrane protein bs-63; ran-binding protein 2-like 1. [refseq;acc:nm_032260]	6122.18
2084	1.05558	5800.22		6122.6
2085	1.05552	5835.4	channel associated protein of synapse-110 (chapsyn-110) (discs, large homolog 2). [swissprot;acc:q15700]	6159.4
2086		5835.44	presynaptic density protein 95 (psd-95) (discs, large homolog 4) (postsynaptic density-95). [swissprot;acc:p78352]	6159.45
2087		5835.45	presynaptic protein sap102 (synapse-associated protein 102) (neuroendocrine-dlg) (ne-dlg) (discs, large homolog 3). [swissprot;acc:q92796]	6159.46
2088		5835.15	presynaptic protein sap97 (synapse-associated protein 97) (discs, large homolog 1) (hdlg). [swissprot;acc:q12959]	6159.11
2089	1.05535	5775.22	putative gtp-binding protein ptd004 (pro2455). [swissprot;acc:q9ntk5]	6094.89
2090	1.05527	5817.07	kh-type splicing regulatory protein (fuse binding protein 2); kh-type splicing regulatory protein (fuse-binding protein 2). [refseq;acc:nm_003685]	6138.59
2091	1.05526	5247.76	maguk p55 subfamily member 6 (veli-associated maguk 1) (vam-1). [swissprot;acc:q9nzw5]	5537.75
2092	1.05525	5817.41	far upstream element-binding protein; far upstream element binding protein; fuse-binding protein. [refseq;acc:nm_003902]	6138.8
2093	1.05524	5817.56	fuse binding protein 3 (fragment). [sptrembl;acc:q92946]	6138.9
2094	1.05522	6682.05	nuclease sensitive element binding protein 1 (y box binding protein-1) (y-box transcription factor) (yb-1) (ccaat-binding transcription factor i subunit a) (cbf-a) (enhancer factor i subunit a) (efi-a) (dna-binding protein b) (dbpb). [swissprot;acc:p16991]	7051.02
2095			dna-binding protein a (cold shock domain protein a) (single-strand dna binding protein nf-gmb). [swissprot;acc:p16989]
2096			germ cell specific y-box binding protein; contrin. [refseq;acc:nm_015982]
2097	1.05512	6024.47	polypeptide n-acetylgalactosaminyltransferase 2; udp-galnac transferase 2. [refseq;acc:nm_004481]	6356.56
2098	1.05512	6024.47	similar to expressed sequence ai415388 (fragment). [sptrembl;acc:q8n428]	6356.56
2099	1.05495	3544.03	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	3359.43
2100	1.05495	3544.03	methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]	3359.43

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/