Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Gene Rank green Value Type Network Comparison Type description Interaction Map network_comparison Filtered red
Results: HTML CSV LaTeX Showing element 351 to 400 of 16578 in total
Value Type  : Ranked
Filtered  : 1
Rank
green
Network Comparison Type
description
Interaction Map
network_comparison
red
88 244.701 Divided potassium voltage-gated channel, shal-related subfamily, member 1; shal-type potassium channel; voltage-gated potassium channel kv4.1. [refseq;acc:nm_004979] Low confidence 1.0855 225.428
298.263 Subtracted regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795] High confidence 48.6 249.663
89 110.265 Divided melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] 1.24949 88.2482
149.799 Subtracted retinoblastoma-associated factor 600. [refseq;acc:nm_020765] Low confidence 15.736 165.535
210.764 Divided star-related lipid transfer protein 7 (stard7) (start domain- containing protein 7) (gtt1 protein). [swissprot;acc:q9nqz5] 1.0853 228.743
298.263 Subtracted putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37] High confidence 48.6 249.663
90 110.265 Divided necdin. [swissprot;acc:q99608] 1.24949 88.2482
216.996 Subtracted neuralized-like. [refseq;acc:nm_004210] Low confidence 15.708 232.704
219.229 Divided tbp-associated factor 2; taf2 rna polymerase ii, tata box binding protein (tbp)-associated factor, 150 kd; tata box binding protein (tbp)-associated factor, rna polymerase ii, b, 150kd; cofactor of initiator function, 150kd subunit. [refseq;acc:nm_003184] 1.08365 237.567
298.263 Subtracted regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081] High confidence 48.6 249.663
91 110.265 Divided melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] 1.24949 88.2482
211.97 Subtracted mouse mammary turmor virus receptor homolog 1. [refseq;acc:nm_152832] Low confidence 15.459 227.429
215.973 Divided oligophrenin 1. [swissprot;acc:o60890] 1.08271 233.837
298.263 Subtracted transcription factor lbx1. [swissprot;acc:p52954] High confidence 48.6 249.663
92 110.265 Divided melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] 1.24949 88.2482
205.364 Subtracted transcription factor e2f1 (e2f-1) (retinoblastoma binding protein 3) (rbbp-3) (prb-binding protein e2f-1) (pbr3) (retinoblastoma-associated protein 1) (rbap-1). [swissprot;acc:q01094] Low confidence 15.133 220.497
215.846 Divided oligophrenin-1 like protein (gtpase regulator associated with focal adhesion kinase). [swissprot;acc:q9una1] 1.08222 233.592
298.263 Subtracted mosaic protein lgn. [swissprot;acc:p81274] High confidence 48.6 249.663
93 110.265 Divided melanoma antigen, family b, 6. [refseq;acc:nm_173523] 1.24949 88.2482
205.364 Subtracted transcription factor e2f2 (e2f-2). [swissprot;acc:q14209] Low confidence 15.133 220.497
228.84 Divided dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552] 1.08082 247.334
298.263 Subtracted regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6] High confidence 48.6 249.663
94 110.265 Divided melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] 1.24949 88.2482
204.212 Subtracted adiponectin receptor 2. [refseq;acc:nm_024551] Low confidence 15.065 219.277
228.693 Divided ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2] 1.08043 247.087
298.263 Subtracted guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471] High confidence 48.6 249.663
95 110.265 Divided melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] 1.24949 88.2482
185.679 amino acid transporter xat2; likely ortholog of mouse aspartate/glutamate transporter 1 (agt1). [refseq;acc:nm_138817] Low confidence 1.0798 200.497
Subtracted 14.818
298.263 rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736] High confidence 48.6 249.663
96 110.265 Divided melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361] 1.24949 88.2482
153.671 Subtracted cyclic-amp-dependent transcription factor atf-3 (activating transcription factor 3). [swissprot;acc:p18847] 48.278 201.949
185.679 Divided y+l amino acid transporter 1 (y(+)l-type amino acid transporter 1) (y+lat-1) (y+lat1) (monocyte amino acid permease 2) (mop-2). [swissprot;acc:q9um01] Low confidence 1.0798 200.497
Subtracted 14.818
97 110.265 Divided melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732] High confidence 1.24949 88.2482
185.679 cystine/glutamate transporter (amino acid transport system xc-) (xct) (calcium channel blocker resistance protein ccbr1). [swissprot;acc:q9upy5] Low confidence 1.0798 200.497
Subtracted 14.818
225.68 amyloid beta a4 precursor protein-binding family a member 1 (neuron- specific x11 protein) (neuronal munc18-1-interacting protein 1) (mint-1) (adapter protein x11alpha). [swissprot;acc:q02410] High confidence 46.072 271.752
98 110.265 Divided melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365] 1.24949 88.2482
160.957 Subtracted proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100] 43.684 204.641
185.679 Divided solute carrier family 7 (cationic amino acid transporter, y+ system), member 6. [refseq;acc:nm_003983] Low confidence 1.0798 200.497
Subtracted 14.818
99 110.265 Divided melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355] High confidence 1.24949 88.2482
160.957 Subtracted jun dimerization protein. [refseq;acc:nm_130469] 43.684 204.641
185.679 Divided eukaryotic translation initiation factor 4b (eif-4b). [swissprot;acc:p23588] Low confidence 1.0798 200.497
Subtracted 14.818
100 110.265 Divided melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363] High confidence 1.24949 88.2482
161.046 Subtracted fos-related antigen 2. [swissprot;acc:p15408] 43.595 204.641
185.679 Divided b(0,+)-type amino acid transporter 1 (b(0,+)at) (glycoprotein- associated amino acid transporter b0,+at1). [swissprot;acc:p82251] Low confidence 1.0798 200.497
Subtracted 14.818

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/