Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type Interaction Map Gene Rank green Filtered description Network Comparison Type network_comparison red
Results: HTML CSV LaTeX Showing element 2225 to 2274 of 3228 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Network Comparison Type  : Divided
Rank
green
description
network_comparison
red
2225 220.108 indolethylamine n-methyltransferase (ec 2.1.1.49) (aromatic alkylamine n-methyltransferase) (indolamine n-methyltransferase) (arylamine n- methyltransferase) (amine n-methyltransferase). [swissprot;acc:o95050] 1.00637 221.509
2226 219.336 cofilin, non-muscle isoform (18 kda phosphoprotein) (p18). [swissprot;acc:p23528] 1.00634 217.955
2227 cofilin, muscle isoform (cofilin 2). [swissprot;acc:q9y281]
2228 213.153 nadph:adrenodoxin oxidoreductase, mitochondrial precursor (ec 1.18.1.2) (adrenodoxin reductase) (ar) (ferredoxin-nadp(+) reductase). [swissprot;acc:p22570] 211.81
2229 219.336 destrin (actin-depolymerizing factor) (adf). [swissprot;acc:p18282] 217.955
2230 ubiquitin fusion degradation protein 1 homolog (ub fusion protein 1). [swissprot;acc:q92890]
2231 223.246 hrd1 protein isoform a; synoviolin1. [refseq;acc:nm_032431] 1.00633 221.842
2232 214.194 43 kda receptor-associated protein of the synapse (rapsyn) (acetylcholine receptor-associated 43 kda protein) (43 kda postsynaptic protein). [swissprot;acc:q13702] 1.00632 215.547
2233 203.691 tripartite motif protein 3 (ring finger protein 22) (brain-expressed ring finger protein). [swissprot;acc:o75382] 1.00631 202.414
2234 225.005 seven in absentia homolog 1. [refseq;acc:nm_003031] 1.00625 223.608
2235 199.711 arginyl-trna synthetase-like; arginine-trna ligase. [refseq;acc:nm_020320] 1.0062 200.95
2236 224.337 protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981] 1.00618 222.959
2237 224.343 bromodomain-containing protein 3 (ring3-like protein). [swissprot;acc:q15059] 222.965
2238 224.337 bromodomain-containing protein 4 (hunk1 protein). [swissprot;acc:o60885] 222.959
2239 224.336 testis-specific bromodomain protein. [refseq;acc:nm_001726] 222.958
2240 224.337 nag14 protein. [refseq;acc:nm_022143] 222.959
2241 224.338 bromodomain-containing protein 2 (ring3 protein) (o27.1.1). [swissprot;acc:p25440] 222.96
2242 207.915 integral membrane protein 2b (transmembrane protein bri) [contains: abri/adan amyloid peptide]. [swissprot;acc:q9y287] 1.00617 209.197
2243 integral membrane protein 2c (transmembrane protein bri3) (npd018). [swissprot;acc:q9nqx7]
2244 integral membrane protein 2a (e25 protein). [swissprot;acc:o43736]
2245 190.448 fibulin-2 precursor. [swissprot;acc:p98095] 1.00614 191.618
2246 224.943 mitochondrial ribosomal protein l18. [refseq;acc:nm_014161] 1.0061 223.58
2247 207.346 sipl protein. [refseq;acc:nm_018269] 1.00609 208.609
2248 220.377 kinesin-like protein kif3c. [swissprot;acc:o14782] 1.00608 219.045
2249 179.999 pyruvate carboxylase, mitochondrial precursor (ec 6.4.1.1) (pyruvic carboxylase) (pcb). [swissprot;acc:p11498] 1.00607 181.091
2250 165.058 likely ortholog of mouse variant polyadenylation protein cstf-64. [refseq;acc:nm_015235] 1.00606 164.064
2251 207.061 e-1 enzyme. [refseq;acc:nm_021204] 208.315
2252 218.498 delta-aminolevulinic acid dehydratase (ec 4.2.1.24) (porphobilinogen synthase) (aladh). [swissprot;acc:p13716] 1.00605 217.185
2253 220.371 kinesin-like protein kif3b (microtubule plus end-directed kinesin motor 3b) (hh0048). [swissprot;acc:o15066] 1.00604 219.047
2254 194.22 ubiquitin-conjugating enzyme e2-17 kda 3 (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2(17)kb 3). [swissprot;acc:p47986] 1.00598 193.065
2255 203.57 alpha-fetoprotein enhancer binding protein (at motif-binding factor) (at-binding transcription factor 1). [swissprot;acc:q15911] 1.00595 202.366
2256 224.869 seven in absentia homolog 2. [refseq;acc:nm_005067] 1.00592 223.546
2257 211.315 nicotinate-nucleotide pyrophosphorylase [carboxylating] (ec 2.4.2.19) (quinolinate phosphoribosyltransferase [decarboxylating]) (qaprtase) (qprtase). [swissprot;acc:q15274] 1.00591 212.563
2258 225.191 hsp90 co-chaperone cdc37 (hsp90 chaperone protein kinase-targeting subunit) (p50cdc37). [swissprot;acc:q16543] 1.00582 223.888
2259 214.606 meiotic recombination protein dmc1/lim15 homolog. [swissprot;acc:q14565] 1.00569 213.391
2260 220.351 leng5 protein. [refseq;acc:nm_024075] 1.00566 221.599
2261 tryptophanyl-trna synthetase (ec 6.1.1.2) (tryptophan--trna ligase) (trprs) (ifp53) (hwrs). [swissprot;acc:p23381]
2262 ribulose-5-phosphate-3-epimerase; ribulose 5-phosphate 3-epimerase. [refseq;acc:nm_006916]
2263 tryptophanyl-trna synthetase, mitochondrial precursor (ec 6.1.1.2) (tryptophan--trna ligase) (trprs) ((mt)trprs). [swissprot;acc:q9ugm6]
2264 thiamin pyrophosphokinase 1; mouse thiamin pyrophosphokinase homolog; thiamine pyrophosphokinase. [refseq;acc:nm_022445]
2265 210.416 mitotic spindle assembly checkpoint protein mad2a (mad2-like 1) (hsmad2). [swissprot;acc:q13257] 1.00561 211.597
2266 probable cation-transporting atpase 1 (ec 3.6.1.-). [swissprot;acc:q9nq11]
2267 tata box binding protein (transcription initiation factor tfiid) (tata-box factor) (tata sequence-binding protein) (tbp). [swissprot;acc:p20226]
2268 203.437 tripartite motif protein 2. [swissprot;acc:q9c040] 1.00556 202.312
2269 218.627 26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832] 217.419
2270 208.69 mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362] 1.00554 207.54
2271 215.436 dimethylaniline monooxygenase [n-oxide forming] 5 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 5) (fmo 5) (dimethylaniline oxidase 5). [swissprot;acc:p49326] 1.00551 216.622
2272 putative dimethylaniline monooxygenase [n-oxide forming] 6 (ec 1.14.13.8) (flavin-containing monooxygenase 6) (fmo 6) (dimethylaniline oxidase 6). [swissprot;acc:o60774]
2273 211.858 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (tak1-binding protein 1). [swissprot;acc:q15750] 1.00546 213.015
2274 214.801 6-phosphogluconate dehydrogenase, decarboxylating (ec 1.1.1.44). [swissprot;acc:p52209] 1.00542 213.642

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/