MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1930 to 1979 of 3228 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	red	green	network_comparison
1930	no value	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]	196.964	198.935	1.01001
1931	EIF3D	eukaryotic translation initiation factor 3 subunit 7 (eif-3 zeta) (eif3 p66) (eif3d). [swissprot;acc:o15371]	219.753	217.574
1932	no value	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]	196.965	198.936
1933	OTC	ornithine carbamoyltransferase, mitochondrial precursor (ec 2.1.3.3) (otcase) (ornithine transcarbamylase). [swissprot;acc:p00480]	215.667	217.82	1.00998
1934	ADD3	gamma adducin (adducin-like protein 70). [swissprot;acc:q9uey8]	224.264	222.055	1.00995
1935	ABHD2	abhydrolase domain containing protein 2 (protein phps1-2). [swissprot;acc:p08910]	218.43	216.279
1936	CKMT2	creatine kinase, sarcomeric mitochondrial precursor (ec 2.7.3.2) (s- mtck) (mib-ck) (basic-type mitochondrial creatine kinase). [swissprot;acc:p17540]	198.3	196.347
1937	QKI	quaking isoform 6. [sptrembl;acc:q9p0x9]	218.43	216.279
1938	no value	creatine kinase, ubiquitous mitochondrial precursor (ec 2.7.3.2) (u- mtck) (mia-ck) (acidic-type mitochondrial creatine kinase). [swissprot;acc:p12532]	198.293	196.341	1.00994
1939	PPIH	peptidyl prolyl isomerase h; cyclophilin h. [refseq;acc:nm_006347]	198.258	196.319	1.00988
1940	CKB	creatine kinase, b chain (ec 2.7.3.2) (b-ck). [swissprot;acc:p12277]	198.19	196.252
1941	PRPF18	prp18 pre-mrna processing factor 18 homolog. [refseq;acc:nm_003675]	198.258	196.319
1942	C21orf55	j domain protein c21orf55. [swissprot;acc:q9nx36]	198.257		1.00987
1943	MEGF11	megf11 protein. [refseq;acc:nm_032445]	224.34	222.147
1944	MEGF10	megf10 protein. [refseq;acc:nm_032446]	224.341	222.148
1945	ADD2	beta adducin (erythrocyte adducin beta subunit). [swissprot;acc:p35612]	224.343	222.151
1946	NFIL3	nuclear factor, interleukin 3 regulated. [refseq;acc:nm_005384]	214.234	212.142	1.00986
1947	PPP1R2	protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236]	125.845	127.083	1.00984
1948	no value	15 kda selenoprotein precursor. [swissprot;acc:o60613]	214.522	212.432
1949	RBPMS	rna-binding protein with multiple splicing (rbp-ms). [swissprot;acc:q93062]	218.794	216.663
1950	VPS18	vacuolar protein sorting 18 (hvps18). [swissprot;acc:q9p253]	215.847	213.747	1.00982
1951	TRIT1	trna isopentenylpyrophosphate transferase. [refseq;acc:nm_017646]	205.876	203.873
1952	KPNA1	importin alpha-1 subunit (karyopherin alpha-1 subunit) (srp1-beta) (rag cohort protein 2) (nucleoprotein interactor 1) (npi-1). [swissprot;acc:p52294]	211.647	213.724	1.00981
1953	PPP1R2P9	type 1 protein phosphatase inhibitor. [refseq;acc:nm_025210]	125.912	127.146	1.0098
1954	KCNAB3	voltage-gated potassium channel beta-3 subunit (k+ channel beta-3 subunit) (kv-beta-3). [swissprot;acc:o43448]	211.632	213.703	1.00979
1955	YIF1A	yip1 interacting factor homolog; yip1p-interacting factor; putative rab5-interacting protein; putative transmembrane protein 54tmp. [refseq;acc:nm_020470]	211.633		1.00978
1956	KCNAB1	voltage-gated potassium channel beta-1 subunit (k+ channel beta-1 subunit) (kv-beta-1). [swissprot;acc:q14722]
1957	YIF1B	similar to putative transmembrane protein; homolog of yeast golgi membrane protein yif1p (yip1p-interacting factor). [refseq;acc:nm_033557]
1958	AKR7A3	aflatoxin b1 aldehyde reductase 2 (ec 1.-.-.-) (afb1-ar 2). [swissprot;acc:o95154]
1959	ABHD3	alpha/beta hydrolase domain containing protein 3; lung alpha/beta hydrolase 3. [refseq;acc:nm_138340]
1960	YIPF5	golgi membrane protein sb140; smooth muscle cell associated protein 5. [refseq;acc:nm_030799]
1961	ABHD1	alpha/beta hydrolase domain containing protein 1 isoform 2; lung alpha/beta hydrolase protein 1. [refseq;acc:nm_152870]
1962	ALDH6A1	methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (ec 1.2.1.27) (mmsdh). [swissprot;acc:q02252]	211.632	213.702
1963	HSPE1	10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	211.633	213.703
1964	RABAC1	rab acceptor 1 (prenylated); prenylated rab acceptor 1. [refseq;acc:nm_006423]
1965	ADD1	alpha adducin (erythrocyte adducin alpha subunit). [swissprot;acc:p35611]	224.432	222.258
1966	REXO2	oligoribonuclease, mitochondrial precursor (ec 3.1.-.-) (small fragment nuclease) (cgi-114). [swissprot;acc:q9y3b8]	211.633	213.703
1967	CHAT	choline o-acetyltransferase (ec 2.3.1.6) (choactase) (choline acetylase) (chat). [swissprot;acc:p28329]	211.632	213.702
1968	KCNAB2	voltage-gated potassium channel beta-2 subunit (k+ channel beta-2 subunit) (kv-beta-2) (hkvbeta2). [swissprot;acc:q13303]	211.633	213.703
1969	AKR7A2	aflatoxin b1 aldehyde reductase 1 (ec 1.-.-.-) (afb1-ar 1) (aldoketoreductase 7). [swissprot;acc:o43488]
1970	KPNA6	importin alpha-6 subunit (karyopherin alpha-5 subunit). [swissprot;acc:o15131]	211.62	213.683	1.00975
1971	CKM	creatine kinase, m chain (ec 2.7.3.2) (m-ck). [swissprot;acc:p06732]	198.258	196.346	1.00974
1972	SEC16B	regucalcin gene promotor region related protein; rgpr-p117. [refseq;acc:nm_033127]	219.777	217.659	1.00973
1973	no value	wiskott-aldrich syndrome protein family member 2 (wasp-family protein member 2) (verprolin homology domain-containing protein 2). [swissprot;acc:q9y6w5]	214.611	212.546	1.00972
1974	WASF3	wiskott-aldrich syndrome protein family member 3 (wasp-family protein member 3) (verprolin homology domain-containing protein 3). [swissprot;acc:q9upy6]
1975	WASF1	wiskott-aldrich syndrome protein family member 1 (wasp-family protein member 1) (verprolin homology domain-containing protein 1). [swissprot;acc:q92558]
1976	RCOR1	rest corepressor. [refseq;acc:nm_015156]
1977	MAF1	homolog of yeast maf1. [refseq;acc:nm_032272]	209.539	207.529	1.00969
1978	SERINC2	tumor differentially expressed protein 2. [refseq;acc:nm_178865]
1979	SERINC3	tumor differentially expressed protein 1 (transmembrane protein sbbi99). [swissprot;acc:q13530]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.