MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Network Comparison Type	Rank	description	Value Type	Interaction Map	Filtered	green	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1844 to 1893 of 6456 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	description	green	network_comparison	red
1844	paired box protein pax-6 (oculorhombin) (aniridia, type ii protein). [swissprot;acc:p26367]	212.417	1.01109	214.773
1845	abl-interactor 2; abl-interacting protein 1 (sh3-containing protein); abl binding protein 3; arg protein tyrosine kinase-binding protein; abl-interactor protein 2b; similar to spectrin sh3 domain binding protein 1. [refseq;acc:nm_005759]	214.702	1.01106	217.077
1846	spectrin sh3 domain binding protein 1; eps8 binding protein; interactor protein ablbp4; abl-interactor protein 1 long; nap1 binding protein. [refseq;acc:nm_005470]	214.698	1.01103	217.066
1847	brain protein 16. [refseq;acc:nm_016458]	219.195	1.011	216.811
1848	bile acid coenzyme a: amino acid n-acyltransferase; glycine n-choloyltransferase. [refseq;acc:nm_001701]	216.064		218.441
1849	peroxisomal acyl-coenzyme a thioester hydrolase 2a (ec 3.1.2.2) (peroxisomal long-chain acyl-coa thioesterase 2) (zap128). [swissprot;acc:p49753]	216.074	1.01097	218.445
1850	adenylyl cyclase-associated protein 1 (cap 1). [swissprot;acc:q01518]	213.587		215.931
1851	peroxisomal acyl-coa thioesterase 2b; likely ortholog of mouse peroxisomal acyl-coa thioesterase 2b. [refseq;acc:nm_152331]	216.08	1.01096	218.448
1852	3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	198.154	1.01095	196.008
1853	tubulin-tyrosine ligase. [refseq;acc:nm_153712]	215.564		217.924
1854	translation initiation factor eif-2b epsilon subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q13144]	224.637	1.0109	222.215
1855	g-rich sequence factor-1 (grsf-1). [swissprot;acc:q12849]	215.542		217.891
1856	heterogeneous nuclear ribonucleoprotein h3 (hnrnp h3) (hnrnp 2h9). [swissprot;acc:p31942]	215.543		217.892
1857	translation initiation factor eif-2b gamma subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q9nr50]	224.637		222.215
1858	heterogeneous nuclear ribonucleoprotein f (hnrnp f). [swissprot;acc:p52597]	215.545	1.01089	217.893
1859	heterogeneous nuclear ribonucleoprotein h (hnrnp h). [swissprot;acc:p31943]	215.547		217.895
1860	heterogeneous nuclear ribonucleoprotein h' (hnrnp h') (ftp-3). [swissprot;acc:p55795]
1861	cytochrome b5 reductase b5r.2. [refseq;acc:nm_016229]	213.147	1.01087	210.856
1862	cytochrome b5 reductase 1 (b5r.1). [refseq;acc:nm_016243]
1863	nadh-cytochrome b5 reductase (ec 1.6.2.2) (b5r). [swissprot;acc:p00387]
1864	fuse-binding protein-interacting repressor isoform b; siah binding protein 1; pyrimidine tract binding splicing factor; ro ribonucleoprotein-binding protein 1; poly-u binding splicing factor puf60. [refseq;acc:nm_014281]	200.89	1.01086	203.071
1865	eukaryotic translation initiation factor 2 subunit 3 (eukaryotic translation initiation factor 2 gamma subunit) (eif-2-gamma). [swissprot;acc:p41091]	224.046		221.639
1866	translation initiation factor eif-2b delta subunit (eif-2b gdp-gtp exchange factor). [swissprot;acc:q9ui10]	224.133		221.725
1867	multisynthetase complex auxiliary component p38 (jtv-1 protein) (pro0992). [swissprot;acc:q13155]	200.89		203.071
1868	protein kinase nyd-sp25. [refseq;acc:nm_033516]	209.895	1.01085	207.642
1869	lanc lantibiotic synthetase component c-like 2; testis-specific adriamycin sensitivity protein; lanc (bacterial lantibiotic synthetase component c)-like 2; g protein-coupled receptor 69b. [refseq;acc:nm_018697]	217.75	1.01082	220.107
1870	lanthionine synthetase c-like protein 1; g protein-coupled receptor 69a; lanc (bacterial lantibiotic synthetase component c)-like 1; lanc (bacterial lantibiotic synthetase component). [refseq;acc:nm_006055]
1871	atp-dependent clp protease atp-binding subunit clpx-like, mitochondrial precursor. [swissprot;acc:o76031]	225.228	1.01081	222.819
1872	dna polymerase delta p38 subunit. [refseq;acc:nm_015584]
1873	scratch; scratch 1. [refseq;acc:nm_031309]	208.305	1.01078	210.55
1874	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	226.271	1.01076	223.862
1875	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]
1876	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]
1877	nucleobindin 1 precursor (calnuc). [swissprot;acc:q02818]	214.467	1.01075	212.186
1878	dna mismatch repair protein mlh1 (mutl protein homolog 1). [swissprot;acc:p40692]
1879	nucleobindin 2 precursor (dna-binding protein nefa). [swissprot;acc:p80303]
1880	cytidine deaminase (ec 3.5.4.5) (cytidine aminohydrolase). [swissprot;acc:p32320]	223.225	1.01074	220.852
1881	dj850e9.1 (novel c2h2 type zinc finger protein similar to drosophila scratch (scrt), slug and xenopus snail) (fragment). [sptrembl;acc:q9nq03]	208.355		210.592
1882	60s ribosomal protein l28. [swissprot;acc:p46779]	213.61	1.0107	215.896
1883	6-phosphofructokinase, type c (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme c) (pfk-c) (6-phosphofructokinase, platelet type). [swissprot;acc:q01813]	242.881	1.01067	240.317
1884	putative gtp-binding protein ptd004 (pro2455). [swissprot;acc:q9ntk5]	217.373	1.01066	215.081
1885	arginase 1 (ec 3.5.3.1) (liver-type arginase). [swissprot;acc:p05089]	206.615	1.01064	204.44
1886	arginase ii, mitochondrial precursor (ec 3.5.3.1) (non-hepatic arginase) (kidney-type arginase). [swissprot;acc:p78540]	206.682	1.01061	204.512
1887	sterile alpha and tir motif containing 1; sterile alpha and heat/armadillo motif protein, ortholog of drosophila. [refseq;acc:nm_015077]	218.577		220.896
1888	immature colon carcinoma transcript 1 (digestion substraction 1) (ds- 1). [swissprot;acc:q14197]	216.131	1.01056	218.414
1889	rab3a interacting protein (rabin3)-like 1. [refseq;acc:nm_013401]	209.067	1.01054	211.27
1890	rab3a interacting protein isoform alpha 1; rabin3; ssx2 interacting protein. [refseq;acc:nm_022456]	209.111		211.314
1891	dna replication licensing factor mcm3 (dna polymerase alpha holoenzyme-associated protein p1) (rlf beta subunit) (p102 protein) (p1-mcm3). [swissprot;acc:p25205]	231.395	1.01051	233.828
1892	kelch-like ech-associated protein 1 (cytosolic inhibitor of nrf2). [swissprot;acc:q14145]
1893	gdp-mannose pyrophosphorylase b isoform 1; mannose-1-phosphate guanylyltransferase; amphoterin induced gene 3. [refseq;acc:nm_013334]	225.17	1.01045	222.842

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.