MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Network Comparison Type	Value Type	description	Rank	green	network_comparison	red	Filtered	Interaction Map

Results: HTML CSV LaTeX

Showing element 1763 to 1812 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1
Interaction Map  : High confidence

description	Rank	green	network_comparison	red
myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]	152	46	1.19565	55
myosin vb (myosin 5b) (fragment). [swissprot;acc:q9ulv0]	150
myosin vc (myosin 5c). [swissprot;acc:q9nqx4]	151
myosin vi. [swissprot;acc:q9um54]	1435	225.468	1.02028	220.987
myosin viia. [swissprot;acc:q13402]	2639	220.386	1.00123	220.658
myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7]	21	245.247	1.32082	185.678
myotubularin-related protein 1 (ec 3.1.3.-). [swissprot;acc:q13613]	3190	0.00001	1	0.00001
myotubularin-related protein 2 (ec 3.1.3.-). [swissprot;acc:q13614]	3166
n-acetylgalactosamine kinase (ec 2.7.1.-) (galnac kinase) (galactokinase 2). [swissprot;acc:q01415]	1336	210.412	1.02257	215.162
n-acetylglucosamine kinase (ec 2.7.1.59) (glcnac kinase). [swissprot;acc:q9uj70]	3022	0.00001	1	0.00001
n-acetylglutamate synthase. [refseq;acc:nm_153006]	1616	226.611	1.01538	223.179
n-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase (ec 2.4.1.149) (poly-n-acetyllactosamine extension enzyme) (i-beta- 1,3-n-acetylglucosaminyltransferase) (ignt) (udp-glcnac:betagal beta- 1,3-n-acetylglucosaminyltransferase 6). [swissprot;acc:o43505]	728	219.708	1.05187	208.874
n-acetyltransferase 5 (ec 2.3.1.-). [swissprot;acc:q9y6d2]	2394	220.826	1.00379	221.662
n-deacetylase/n-sulfotransferase (heparan glucosaminyl) 3. [refseq;acc:nm_004784]	1354	223.475	1.02208	228.409
n-deacetylase/n-sulfotransferase 4. [refseq;acc:nm_022569]	1355
n-myc proto-oncogene protein. [swissprot;acc:p04198]	882	219.008	1.03924	227.601
n-terminal acetyltransferase complex ard1 subunit homolog (ec 2.3.1.-). [swissprot;acc:p41227]	438	216.674	1.07869	233.723
nadh-cytochrome b5 reductase (ec 1.6.2.2) (b5r). [swissprot;acc:p00387]	1863	213.147	1.01087	210.856
nadh-ubiquinone oxidoreductase 13 kda-a subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-a) (ci-13kd-a). [swissprot;acc:o75380]	1762	230.595	1.01238	233.45
nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]	3005	0.00001	1	0.00001
nadh-ubiquinone oxidoreductase 18 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-18 kda) (ci-18 kda) (complex i- aqdq) (ci-aqdq). [swissprot;acc:o43181]	119	259.004	1.23157	318.982
nadh-ubiquinone oxidoreductase 23 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-23kd) (ci-23kd) (tyky subunit). [swissprot;acc:o00217]	885	219.017	1.03917	227.596
nadh-ubiquinone oxidoreductase 24 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3). [swissprot;acc:p19404]	2795	0.00001	1	0.00001
nadh-ubiquinone oxidoreductase 30 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-30kd) (ci-30kd). [swissprot;acc:o75489]	3081
nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	2954
nadh-ubiquinone oxidoreductase 49 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-49kd) (ci-49kd). [swissprot;acc:o75306]	2878
nadh-ubiquinone oxidoreductase b14 subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b14) (ci-b14). [swissprot;acc:p56556]	630	202.141	1.05993	214.256
nadh-ubiquinone oxidoreductase b22 subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b22) (ci-b22). [swissprot;acc:q9y6m9]	1096	206.339	1.02911	212.345
nadh-ubiquinone oxidoreductase pdsw subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-pdsw) (ci-pdsw). [swissprot;acc:o96000]	2386	212.983	1.00393	213.82
nadh-ubiquinone oxidoreductase subunit b17.2 (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b17.2) (ci-b17.2) (cib17.2) (13 kda differentiation-associated protein). [swissprot;acc:q9ui09]	118	228.934	1.24382	284.753
nadph-cytochrome p450 reductase (ec 1.6.2.4) (cpr) (p450r). [swissprot;acc:p16435]	274	267.352	1.10763	241.373
nadph:adrenodoxin oxidoreductase, mitochondrial precursor (ec 1.18.1.2) (adrenodoxin reductase) (ar) (ferredoxin-nadp(+) reductase). [swissprot;acc:p22570]	2228	213.153	1.00634	211.81
nag14 protein. [refseq;acc:nm_022143]	2240	224.337	1.00618	222.959
nanos (fragment). [sptrembl;acc:q8wy41]	2803	0.00001	1	0.00001
nardilysin precursor (ec 3.4.24.61) (n-arginine dibasic convertase) (nrd convertase) (nrd-c). [swissprot;acc:o43847]	2633	225.195	1.00135	224.891
nascent-polypeptide-associated complex alpha polypeptide. [refseq;acc:nm_005594]	888	204.05	1.03909	212.027
necdin. [swissprot;acc:q99608]	90	110.265	1.24949	88.2482
nefa-interacting nuclear protein nip30. [refseq;acc:nm_024946]	2608	215.799	1.0014	215.497
neighbor of cox4. [swissprot;acc:o43402]	1818	217.926	1.01164	220.462
nemo-like kinase; likely ortholog of mouse nemo like kinase. [refseq;acc:nm_016231]	1060	211.648	1.03078	218.162
neural cell adhesion molecule l1 precursor (n-cam l1) (cd171 antigen). [swissprot;acc:p32004]	2740	198.321	1.00022	198.278
neural wiskott-aldrich syndrome protein (n-wasp). [swissprot;acc:o00401]	559	194.452	1.06612	207.309
neuralized-like. [refseq;acc:nm_004210]	117	266.948	1.24491	332.326
neurocalcin delta. [swissprot;acc:p29554]	1182	230.931	1.02589	225.104
neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079]	129	114	1.21277	94
neuroepithelial cell transforming gene 1; guanine nucleotide regulatory protein (oncogene); rho guanine nucleotide exchange factor (gef) 8. [refseq;acc:nm_005863]	785	233.508	1.04685	244.447
neurogenic differentiation factor 1 (neurod1) (neurod). [swissprot;acc:q13562]	333	284	1.09859	312
neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	329
neurogenic differentiation factor 4 (neurod4). [swissprot;acc:q9hd90]	334
neurogenic differentiation factor 6 (neurod6) (my051 protein). [swissprot;acc:q96nk8]	332

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.