MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	description	Value Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1080 to 1129 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	description	Value Type
3025	HMG1L1	dj579f20.1 (high-mobility group (nonhistone chromosomal) protein 1-like 1). [sptrembl;acc:q9nqj4]	Rooted
3026	SLC36A1	solute carrier family 36 member 1; proton / amino acid symporter; lysosomal amino acid transporter 1. [refseq;acc:nm_078483]	Measured
			Ranked
			Squared
			Rooted
3027	TSFM	elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]	Measured
			Ranked
			Squared
			Rooted
3028	C13orf1	clll6 protein. [refseq;acc:nm_020456]	Measured
			Ranked
			Squared
			Rooted
3029	DNAI1	dynein intermediate chain 1, axonemal (axonemal dynein intermediate chain 1). [swissprot;acc:q9ui46]	Measured
			Ranked
			Squared
			Rooted
3030	C6orf35	uncharacterized bone marrow protein bm033. [refseq;acc:nm_018452]	Measured
			Ranked
			Squared
			Rooted
3031	SPOP	speckle-type poz protein. [swissprot;acc:o43791]	Measured
			Ranked
			Squared
			Rooted
3032	LYZL1	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]	Measured
			Ranked
			Squared
			Rooted
3033	GPAM	glycerol-3-phosphate acyltransferase, mitochondrial precursor (ec 2.3.1.15) (gpat). [swissprot;acc:q9hcl2]	Measured
			Ranked
			Squared
			Rooted
3034	CRIPT	postsynaptic protein cript; hspc139 protein. [refseq;acc:nm_014171]	Measured
			Ranked
			Squared
			Rooted
3035	TGFB3	transforming growth factor beta 3 precursor (tgf-beta 3). [swissprot;acc:p10600]	Measured
			Ranked
			Squared
			Rooted
3036	PGF	placenta growth factor precursor (plgf). [swissprot;acc:p49763]	Measured
			Ranked
			Squared
			Rooted
3037	VPS4B	skd1 protein (vacuolar sorting protein 4b). [swissprot;acc:o75351]	Measured
			Ranked
			Squared
			Rooted
3038	no value	spectrin alpha chain, brain (spectrin, non-erythroid alpha chain) (alpha-ii spectrin) (fodrin alpha chain). [swissprot;acc:q13813]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.