MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Filtered	Network Comparison Type	Value Type	network_comparison	Interaction Map	Rank	red	green	description

Results: HTML CSV LaTeX

Showing element 3682 to 3731 of 77072 in total

Filtered  : 0
Network Comparison Type  : Divided
Value Type  : Squared

network_comparison	Interaction Map	Rank	red	green	description
1.45875	Low confidence	169	1171.32	802.961	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]
1.45943		168	220.333	150.972	poly (adp-ribose) glycohydrolase. [refseq;acc:nm_003631]
1.4611		167	7810.49	5345.62	small glutamine rich protein with tetratricopeptide repeats 2. [refseq;acc:nm_019072]
1.46537	High confidence	185	0.125207	0.0854438	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]
	Low confidence	166
1.47582		165	10450.9	7081.4	fos-related antigen 2. [swissprot;acc:p15408]
1.47811	High confidence	184	4.23965	2.86829	transcription elongation factor a protein 1 (transcription elongation factor s-ii protein 1) (transcription elongation factor tfiis.o). [swissprot;acc:p23193]
1.47937		183	37.9786	56.1843	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]
1.47947	Low confidence	164	218.433	147.643	transcription factor bteb4 (basic transcription element binding- protein 4) (bte-binding protein 4) (krueppel-like factor 16) (novel sp1-like zinc finger transcription factor 2) (transcription factor nslp2). [swissprot;acc:q9bxk1]
1.47953		163	1304.12	1929.49	putative inorganic polyphosphate/atp-nad kinase (ec 2.7.1.23) (poly(p)/atp nad kinase). [swissprot;acc:o95544]
1.4848		162	5366.16	7967.67	putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]
1.49026	High confidence	182	323.856	482.631	crooked neck-like protein 1 (crooked neck homolog) (hcrn) (cgi-201) (mstp021). [swissprot;acc:q9bzj0]
1.49065	Low confidence	161	40110.9	59791.4	ena/vasodilator stimulated phosphoprotein-like protein (ena/vasp-like protein). [swissprot;acc:q9ui08]
1.49232	High confidence	181	140.822	210.151	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]
	Low confidence	160
1.49332	High confidence	180	38799.5	25982	sodium/potassium-transporting atpase alpha-2 chain precursor (ec 3.6.3.9) (sodium pump 2) (na+/k+ atpase 2). [swissprot;acc:p50993]
1.49742		179	0.284967	0.426714	suppressor of actin 1. [refseq;acc:nm_014016]
1.49759	Low confidence	159	11376	7596.22	e1a binding protein p400; p400 swi2/snf2-related protein; cagh32 protein; trinucleotide repeat containing 12. [refseq;acc:nm_015409]
1.50019	High confidence	177	73.1683	109.766	hepatitis c virus core-binding protein 6; cervical cancer oncogene 3. [refseq;acc:nm_023934]
		178			dc11 protein. [refseq;acc:nm_020186]
	Low confidence	157			hepatitis c virus core-binding protein 6; cervical cancer oncogene 3. [refseq;acc:nm_023934]
		158			dc11 protein. [refseq;acc:nm_020186]
1.50186		156	4.8166	7.23384	williams beuren syndrome chromosome region 21 isoform 1. [refseq;acc:nm_148912]
1.50384		155	156.943	236.017	dead-box protein. [refseq;acc:nm_018665]
1.5131		154	8679.33	13132.7	glycine receptor alpha-3 chain precursor. [swissprot;acc:o75311]
1.52379		153	627.347	955.944	bromodomain adjacent to zinc finger domain protein 1a (atp-utilizing chromatin assembly and remodeling factor 1) (hacf1) (atp-dependent chromatin remodelling protein) (williams syndrome transcription factor-related chromatin remodeling factor 180) (wcrf180) (hwalp1) (chrac subunit acf1) (hspc317). [swissprot;acc:q9nrl2]
1.52448		152	1391.77	2121.73	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]
1.54359		151	135.845	209.689	testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562]
1.55954	High confidence	175	48.5538	75.7214	cytochrome p450 4f8 (ec 1.14.14.1) (cypivf8). [swissprot;acc:p98187]
		176			cytochrome p450 4f2 (ec 1.14.13.30) (cypivf2) (leukotriene-b4 omega- hydroxylase) (leukotriene-b4 20-monooxygenase) (cytochrome p450- ltb-omega). [swissprot;acc:p78329]
1.5596		174	48.3438	75.3968	cytochrome p450 4f11 (ec 1.14.14.1) (cypivf11). [swissprot;acc:q9hbi6]
1.55963		173	48.239	75.2348	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]
1.55986		172	47.4746	74.0536	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]
1.5625	Low confidence	150	1.3671	2.13609	protein c20orf142 precursor. [swissprot;acc:q8n6m3]
1.5628	High confidence	171	1592.06	2488.07	trans-prenyltransferase; polyprenyl pyrophosphate synthetase. [refseq;acc:nm_014317]
1.56969	Low confidence	149	1576.49	2474.6
1.57726	High confidence	170	175.528	276.854	calcyphosine. [swissprot;acc:q13938]
1.58189		169	14.0914	8.90793	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]
1.58656		168	338.863	213.584	lipocalin-interacting membrane receptor. [refseq;acc:nm_018113]
1.58702	Low confidence	148	250.49	157.837
1.58925	High confidence	167	168.446	105.991	dystrobrevin binding protein 1; dysbindin. [refseq;acc:nm_032122]
1.58979	Low confidence	147	221.736	352.514	rho guanine nucleotide exchange factor (gef) 12; leukemia-associated rho guanine nucleotide exchange factor. [refseq;acc:nm_015313]
1.59322	High confidence	166	220.039	350.57	hsp90 co-chaperone cdc37 (hsp90 chaperone protein kinase-targeting subunit) (p50cdc37). [swissprot;acc:q16543]
1.59894		165	54383.4	34012.2	myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]
1.60218		164	145.887	91.0551	daz associated protein 1 isoform b; deleted in azoospermia associated protein 1. [refseq;acc:nm_018959]
1.6022		163	5071.93	3165.6	p28 ing5. [refseq;acc:nm_032329]
1.62716		157	6123.28	3763.18	udp-glucuronosyltransferase 2b17 precursor, microsomal (ec 2.4.1.17) (udpgt) (c19-steroid specific udp-glucuronosyltransferase). [swissprot;acc:o75795]
		158			udp-glucuronosyltransferase 2b11 precursor, microsomal (ec 2.4.1.17) (udpgt). [swissprot;acc:o75310]
		159			udp-glucuronosyltransferase 2b4 precursor, microsomal (ec 2.4.1.17) (udpgt) (hyodeoxycholic acid) (hlug25) (udpgth-1). [swissprot;acc:p06133]
		160			glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.