MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Filtered	description	Rank	Value Type	green	Interaction Map	network_comparison	Network Comparison Type	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Filtered  : 0
Network Comparison Type  : Divided

description	Rank	Value Type	green	Interaction Map	network_comparison	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	37	Measured	934.348	High confidence	2.79409	334.401
		Squared	1034.13		10.2338	101.05
	53	Rooted	18.0183		1.5213	11.844
	131	Measured	851.77	Low confidence	1.31954	645.504
	146	Squared	1268.51		1.63527	775.72
	242	Ranked	13895.8	High confidence	1.09822	15260.6
	537	Rooted	17.0804	Low confidence	1.04801	16.298
	629	Ranked	13590.3		1.02915	13205.3
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829]	627		10050.9		1.02953	10347.7
	768	Rooted	39.5126		1.0106	39.0982
	778	Measured	4869.42		1.00902	4825.89
	815	Squared	40451		1.00447	40270.8
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	19	Measured	26.1599	High confidence	11.6763	305.45
	26	Squared	0.344399		128.828	44.3683
		Rooted	3.80565		3.62106	13.7805
	47	Ranked	18499.2		1.42943	12941.7
	131	Rooted	9.42485	Low confidence	1.20585	11.365
	171	Measured	181.734		1.22585	222.779
	384	Ranked	14695.2		1.08587	13533.1
	697	Squared	296.481		1.03806	307.765
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	316		7355.46	High confidence	1.17196	8620.27
	370	Rooted	32.0298		1.04188	30.7424
	379	Ranked	10806		1.03909	11228.4
	451	Measured	2642.79		1.01545	2683.61
	763	Squared	6490.54	Low confidence	1.01738	6603.33
	771	Measured	1609.88		1.01017	1593.68
	793	Rooted	23.2445		1.00582	23.11
	825	Ranked	11854.2		1.00181	11832.8
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	328	Squared	5878.56	High confidence	1.14785	6747.71
	458	Rooted	28.5146		1.01531	28.0847
	474	Measured	2263.85		1.00763	2281.12
	495	Ranked	11748.1		1.00195	11725.2
	591	Squared	14694	Low confidence	1.07533	15800.9
	665	Ranked	11538		1.02285	11801.6
	728	Rooted	26.5693		1.01548	26.1642
	785	Measured	2331.31		1.00797	2349.9
3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	299	Ranked	11512.3	High confidence	1.07178	12338.7
	438	Rooted	44.9836		1.025	43.8864
	453	Ranked	11512.3	Low confidence	1.07178	12338.7
	492	Measured	5046.33	High confidence	1.00159	5038.33
	493	Squared	17901.1		1	17901.1
	662	Rooted	44.9836	Low confidence	1.025	43.8864
	822	Measured	5046.33		1.00159	5038.33
	836	Squared	17901.1		1	17901.1
3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	327	Ranked	10466.5	High confidence	1.05751	9897.29
	376	Rooted	31.1453		1.03923	32.3671
	438	Measured	2853.65		1.0252	2925.57
	442	Rooted	25.4539	Low confidence	1.06963	27.2263
	477	Squared	18218.3	High confidence	1.0074	18353.1
	501	Ranked	11352.1	Low confidence	1.0588	10721.7

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.