MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Network Comparison Type	Value Type	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 16530 to 16578 of 16578 in total

Value Type  : Ranked
Interaction Map  : Low confidence
Filtered  : 1

Rank	description	Network Comparison Type	red	green	network_comparison
5037	myeloblast kiaa0230 (fragment). [sptrembl;acc:q92626]	Subtracted	0	0	0
5038	testis specific leucine rich repeat protein. [refseq;acc:nm_012472]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5039	major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5040	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5041	n-acetylglucosamine kinase (ec 2.7.1.59) (glcnac kinase). [swissprot;acc:q9uj70]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5042	transthyretin precursor (prealbumin) (tbpa) (ttr) (attr). [swissprot;acc:p02766]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5043	late endosomal/lysosomal mp1 interacting protein (p14) (hspc003). [swissprot;acc:q9y2q5]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5044	langerhans cell specific c-type lectin. [refseq;acc:nm_015717]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5045	putative tumor suppressor 101f6. [refseq;acc:nm_007022]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5046	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5047	double-stranded rna-binding zinc finger protein jaz. [refseq;acc:nm_012279]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5048	mitogen-activated protein kinase kinase 1 interacting protein 1 (mek binding partner 1) (mp1) (pro2783). [swissprot;acc:q9uha4]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5049	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Divided	177.3	177.3	1
		Subtracted			0
5050	lipin 2. [swissprot;acc:q92539]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5051	sam domain and hd domain-containing protein 1 (dendritic cell-derived ifng-induced protein) (dcip) (monocyte protein 5) (mop-5). [swissprot;acc:q9y3z3]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5052	tubulin tyrosine ligase-like protein 1. [swissprot;acc:o95922]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5053	gamma-glutamyltransferase. [sptrembl;acc:q14390]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5054	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5055	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5056	putative nadh oxidoreductase complex i subunit homolog. [sptrembl;acc:q96q80]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5057	leucine rich repeat (in flii) interacting protein 2. [refseq;acc:nm_006309]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5058	carcinoma related gene. [refseq;acc:nm_016041]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5059	core-binding factor, beta subunit (cbf-beta) (polyomavirus enhancer binding protein 2 beta subunit) (pebp2-beta) (pea2-beta) (sl3-3 enhancer factor 1 beta subunit) (sl3/akv core-binding factor beta subunit). [swissprot;acc:q13951]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5060	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (methyl methanesulfonate (mmf)-inducible fragment protein 1). [swissprot;acc:q15011]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0
5061	runt-related transcription factor 3 (core-binding factor, alpha 3 subunit) (cbf-alpha 3) (acute myeloid leukemia 2 protein) (oncogene aml-2) (polyomavirus enhancer binding protein 2 alpha c subunit) (pebp2-alpha c) (pea2-alpha c) (sl3-3 enhancer factor 1 alpha c subunit) (sl3/akv core-binding factor alpha c subunit). [swissprot;acc:q13761]	Divided	0.00001	0.00001	1
		Subtracted	0	0	0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.