MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1610 to 1659 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Value Type
3158	integrin alpha-6 precursor (vla-6) (cd49f). [swissprot;acc:p23229]	Ranked
		Squared
		Rooted
3159	trinucleotide repeat containing 6; edie; gw182 autoantigen. [refseq;acc:nm_014494]	Measured
		Ranked
		Squared
		Rooted
3160	cyclin k. [swissprot;acc:o75909]	Measured
		Ranked
		Squared
		Rooted
3161	brca1 associated protein. [refseq;acc:nm_006768]	Measured
		Ranked
		Squared
		Rooted
3162	phosphatidylethanolamine-binding protein (pebp) (prostatic binding protein) (hcnppp) (neuropolypeptide h3) (raf kinase inhibitor protein) (rkip) [contains: hippocampal cholinergic neurostimulating peptide (hcnp)]. [swissprot;acc:p30086]	Measured
		Ranked
		Squared
		Rooted
3163	ccr4-not transcription complex, subunit 3; not3 (negative regulator of transcription 3, yeast) homolog. [refseq;acc:nm_014516]	Measured
		Ranked
		Squared
		Rooted
3164	transcription factor ap-2 gamma (ap2-gamma) (activating enhancer- binding protein 2 gamma) (transcription factor erf-1). [swissprot;acc:q92754]	Measured
		Ranked
		Squared
		Rooted
3165	gpi transamidase component pig-s (phosphatidylinositol-glycan biosynthesis, class s protein). [swissprot;acc:q96s52]	Measured
		Ranked
		Squared
		Rooted
3166	myotubularin-related protein 2 (ec 3.1.3.-). [swissprot;acc:q13614]	Measured
		Ranked
		Squared
		Rooted
3167	centromere/kinetochore protein zw10 homolog. [swissprot;acc:o43264]	Measured
		Ranked
		Squared
		Rooted
3168	cop-coated vesicle membrane protein p24 precursor (p24a). [swissprot;acc:q15363]	Measured
		Ranked
		Squared
		Rooted
3169	transcriptional repressor nf-x1 (ec 6.3.2.-) (nuclear transcription factor, x box-binding, 1). [swissprot;acc:q12986]	Measured
		Ranked
		Squared
		Rooted
3170	ecotropic virus integration 1 site protein. [swissprot;acc:q03112]	Measured
		Ranked
		Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.