MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	Network Comparison Type	Value Type	Interaction Map	green	description	network_comparison	red	Filtered

Results: HTML CSV LaTeX

Showing element 1558 to 1607 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	green	description	network_comparison	red
1558	192.977	c-terminal binding protein 2 (ctbp2). [swissprot;acc:p56545]	1.01655	196.171
1559	192.996	b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [refseq;acc:nm_181844]		196.191
1560	170.455	p66 alpha. [refseq;acc:nm_017660]	1.01651	167.687
1561		transcription repressor p66 beta component of the mecp1 complex. [refseq;acc:nm_020699]
1562		tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]
1563	214.739	atp synthase gamma chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p36542]	1.01648	218.277
1564		atp synthase oligomycin sensitivity conferral protein, mitochondrial precursor (ec 3.6.3.14) (oscp). [swissprot;acc:p48047]
1565	224.767	eukaryotic translation initiation factor 3 subunit 11 (eif-3 p25) (eif3k) (muscle specific gene m9 protein) (ptd001) (hspc029) (arg134). [swissprot;acc:q9ubq5]	1.01646	221.128
1566		erythroid differentiation and denucleation factor 1. [swissprot;acc:o60584]
1567		bardet-biedl syndrome 7 protein isoform a; bbs2-like 1. [refseq;acc:nm_176824]
1568		ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
1569		lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]
1570		protein c20orf45 (cgi-107). [swissprot;acc:q9y3b1]
1571		eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [swissprot;acc:q9y262]
1572		putative rna-binding protein 7 (rna binding motif protein 7). [swissprot;acc:q9y580]
1573	214.573	r3h domain protein 1. [swissprot;acc:q15032]		218.105
1574	218.982	tata element modulatory factor (tmf). [swissprot;acc:p82094]	1.01645	222.585
1575		scy1-like 1; telomerase regulation-associated protein; ht019 protein; telomerase regulation-associated protein; n-terminal kinase-like protein; teratoma-associated tyrosine kinase; n-terminal kinase-like. [refseq;acc:nm_020680]
1576		nuclear pore complex protein nup98 (nucleoporin nup98) (98 kda nucleoporin). [swissprot;acc:p52948]
1577		ammecr1 protein. [refseq;acc:nm_015365]
1578		mrna-associated protein mrnp 41 (rae1 protein homolog). [swissprot;acc:p78406]
1579	209.732	cda11 protein. [refseq;acc:nm_032026]	1.01644	213.181
1580	170.769	g2/mitotic-specific cyclin b2. [swissprot;acc:o95067]	1.01637	168.018
1581	170.753	cell division protein kinase 3 (ec 2.7.1.-). [swissprot;acc:q00526]		168.002
1582	170.844	g2/mitotic-specific cyclin b1. [swissprot;acc:p14635]	1.01634	168.098
1583	170.837	cell division protein kinase 2 (ec 2.7.1.-) (p33 protein kinase). [swissprot;acc:p24941]		168.091
1584	220.432	6-phosphogluconolactonase (ec 3.1.1.31) (6pgl). [swissprot;acc:o95336]	1.01633	216.891
1585	170.888	cell division control protein 2 homolog (ec 2.7.1.-) (p34 protein kinase) (cyclin-dependent kinase 1) (cdk1). [swissprot;acc:p06493]	1.01631	168.145
1586	225.79	adapter-related protein complex 1 beta 1 subunit (beta-adaptin 1) (adaptor protein complex ap-1 beta-1 subunit) (golgi adaptor ha1/ap1 adaptin beta subunit) (clathrin assembly protein complex 1 beta large chain). [swissprot;acc:q10567]		222.166
1587	216.598	protein c20orf4 (protein cgi-23) (pro0225). [swissprot;acc:q9y312]	1.0163	220.129
1588	180.725	ring finger protein 25 (ec 6.3.2.-). [swissprot;acc:q96bh1]	1.01626	177.834
1589	227.219	valyl-trna synthetase 2 (ec 6.1.1.9) (valine--trna ligase 2) (valrs 2) (g7a). [swissprot;acc:p26640]	1.01624	223.589
1590	228.769	thymidylate synthase (ec 2.1.1.45) (ts) (tsase). [swissprot;acc:p04818]	1.01621	225.119
1591		dihydrofolate reductase (ec 1.5.1.3). [swissprot;acc:p00374]
1592		stromal cell-derived factor 2 precursor (sdf-2). [swissprot;acc:q99470]
1593		stromal cell-derived factor 2-like protein 1 precursor (sdf2 like protein 1) (pwp1-interacting protein 8). [swissprot;acc:q9hcn8]
1594	225.731	adapter-related protein complex 1 gamma 2 subunit (gamma2-adaptin) (adaptor protein complex ap-1 gamma-2 subunit) (g2ad). [swissprot;acc:o75843]	1.0162	222.133
1595		adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]	1.01619	222.134
1596		adapter-related protein complex 1 gamma 1 subunit (gamma-adaptin) (adaptor protein complex ap-1 gamma-1 subunit) (golgi adaptor ha1/ap1 adaptin gamma-1 subunit) (clathrin assembly protein complex 1 gamma-1 large chain). [swissprot;acc:o43747]
1597		adapter-related protein complex 1 sigma 1c subunit (sigma-adaptin 1c) (adaptor protein complex ap-1 sigma-1c subunit) (golgi adaptor ha1/ap1 adaptin sigma-1c subunit) (clathrin assembly protein complex 1 sigma- 1c small chain) (sigma 1c subunit of ap-1 clathrin). [swissprot;acc:q96pc3]
1598		adapter-related protein complex 1 sigma 1a subunit (sigma-adaptin 1a) (adaptor protein complex ap-1 sigma-1a subunit) (golgi adaptor ha1/ap1 adaptin sigma-1a subunit) (clathrin assembly protein complex 1 sigma- 1a small chain) (clathrin coat assembly protein ap19) (ha1 19 kda subunit) (sigma 1a subunit of ap-1 clathrin). [swissprot;acc:q00382]
1599	214.404	dystrobrevin binding protein 1; dysbindin. [refseq;acc:nm_032122]	1.01617	217.871
1600	225.675	adapter-related protein complex 2 beta 1 subunit (beta-adaptin) (plasma membrane adaptor ha2/ap2 adaptin beta subunit) (clathrin assembly protein complex 2 beta large chain) (ap105b). [swissprot;acc:p21851]	1.01608	222.103
1601	213.842	phosphomannomutase 2 (ec 5.4.2.8) (pmm 2). [swissprot;acc:o15305]	1.01602	217.268
1602	213.914	phosphomannomutase 1 (ec 5.4.2.8) (pmm 1) (pmmh-22). [swissprot;acc:q92871]	1.01599	217.334
1603	213.22	heat shock factor binding protein 1. [swissprot;acc:o75506]	1.01595	216.62
1604	211.614	protein kinase clk2 (ec 2.7.1.-) (cdc-like kinase 2). [swissprot;acc:p49760]	1.01593	214.984
1605	213.916	hepatocyte nuclear factor 3-alpha (hnf-3a) (forkhead box protein a1). [swissprot;acc:p55317]	1.01592	217.322
1606	204.662	apolipoprotein a-i binding protein; apoa-i binding protein. [refseq;acc:nm_144772]	1.0159	207.916
1607	211.622	protein kinase clk3 (ec 2.7.1.-) (cdc-like kinase 3). [swissprot;acc:p49761]	1.01588	214.982

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.