MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Gene	Value Type	description	Rank	Filtered	Interaction Map	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1558 to 1607 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1
Interaction Map  : High confidence

description	Rank	red	green	network_comparison
lipopolysaccharide-binding protein precursor (lbp). [swissprot;acc:p18428]	753	224.434	235.583	1.04968
lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	1569	221.128	224.767	1.01646
liv-1 protein, estrogen regulated. [refseq;acc:nm_012319]	164	209.299	249.187	1.19058
loh1cr12. [refseq;acc:nm_058169]	827	230.087	220.579	1.0431
lon protease homolog, mitochondrial precursor (ec 3.4.21.-) (lon protease-like protein) (lonp) (lonhs). [swissprot;acc:p36776]	1810	223.214	225.827	1.01171
low affinity immunoglobulin epsilon fc receptor (lymphocyte ige receptor) (fc-epsilon-rii) (cd23) (blast-2) (immunoglobulin e-binding factor). [swissprot;acc:p06734]	419	233.539	253.197	1.08417
luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	205	228.1	200.968	1.13501
luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	206	228.085	201.006	1.13472
lupus la protein (sjogren syndrome type b antigen) (ss-b) (la ribonucleoprotein) (la autoantigen). [swissprot;acc:p05455]	536	242.531	227.136	1.06778
lyl-1 protein (lymphoblastic leukemia derived sequence 1). [swissprot;acc:p12980]	3107	0.00001	0.00001	1
lymphoid enhancer binding factor 1 (lef-1) (t cell-specific transcription factor 1-alpha) (tcf1-alpha). [swissprot;acc:q9uju2]	603	225.829	212.945	1.0605
lysophospholipase i; lysophospholipase 1; lysophospholipid-specific lysophospholipase; acyl-protein thioesterase-1. [refseq;acc:nm_006330]	2410	194.407	193.706	1.00362
lysophospholipase ii; acyl-protein thioesterase. [refseq;acc:nm_007260]	2412
lysosomal acid lipase/cholesteryl ester hydrolase precursor (ec 3.1.1.13) (lal) (acid cholesteryl ester hydrolase) (sterol esterase) (lipase a) (cholesteryl esterase). [swissprot;acc:p38571]	2116	214.632	213.14	1.007
lysosomal alpha-mannosidase precursor (ec 3.2.1.24) (mannosidase, alpha b) (lysosomal acid alpha-mannosidase) (laman) (mannosidase alpha class 2b member 1). [swissprot;acc:o00754]	2210	199.129	200.413	1.00645
lysosomal trafficking regulator (beige homolog). [swissprot;acc:q99698]	2929	0.00001	0.00001	1
lysyl-trna synthetase (ec 6.1.1.6) (lysine--trna ligase) (lysrs). [swissprot;acc:q15046]	1101	220.291	226.584	1.02857
m-phase inducer phosphatase 1 (ec 3.1.3.48) (dual specificity phosphatase cdc25a). [swissprot;acc:p30304]	1343	258.558	252.916	1.02231
m-phase inducer phosphatase 2 (ec 3.1.3.48) (dual specificity phosphatase cdc25b). [swissprot;acc:p30305]	1642	260.269	256.531	1.01457
m-phase inducer phosphatase 3 (ec 3.1.3.48) (dual specificity phosphatase cdc25c). [swissprot;acc:p30307]	1504	259.439	254.797	1.01822
mab-21-like protein 1; mab-21-like 1. [refseq;acc:nm_005584]	2786	0.00001	0.00001	1
mab-21-like protein 2; mab-21-like 2. [refseq;acc:nm_006439]	2783
mad protein (max dimerizer). [swissprot;acc:q05195]	253	228	204.333	1.11583
mago nashi protein homolog. [swissprot;acc:p50606]	2864	0.00001	0.00001	1
maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168]	1467	228.513	232.983	1.01956
maguk p55 subfamily member 3 (mpp3 protein) (discs, large homolog 3). [swissprot;acc:q13368]	2088	218.124	216.433	1.00781
maguk p55 subfamily member 6 (veli-associated maguk 1) (vam-1). [swissprot;acc:q9nzw5]	1479	228.469	232.855	1.0192
major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	3013	0.00001	0.00001	1
malate dehydrogenase, cytoplasmic (ec 1.1.1.37). [swissprot;acc:p40925]	3213
malate dehydrogenase, mitochondrial precursor (ec 1.1.1.37). [swissprot;acc:p40926]	571	238.529	254.099	1.06528
maleylacetoacetate isomerase (ec 5.2.1.2) (maai) (glutathione s- transferase zeta 1) (ec 2.5.1.18) (gstz1-1). [swissprot;acc:o43708]	954	267.447	276.773	1.03487
malonyl-coa decarboxylase, mitochondrial precursor (ec 4.1.1.9) (mcd). [swissprot;acc:o95822]	1634	215.772	212.596	1.01494
mam domain containing glycosylphosphatidylinositol anchor 1; glycosyl-phosphatidyl-inositol-mam. [refseq;acc:nm_153487]	3070	0.00001	0.00001	1
mannose-6-phosphate isomerase (ec 5.3.1.8) (phosphomannose isomerase) (pmi) (phosphohexomutase). [swissprot;acc:p34949]	1522	219.306	223.179	1.01766
mannose-p-dolichol utilization defect 1 protein (suppressor of lec15 and lec35 glycosylation mutation homolog) (sl15). [swissprot;acc:o75352]	929	225.955	218.015	1.03642
mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	2	15	28	1.86667
map kinase-activated protein kinase 2 (ec 2.7.1.-) (mapk-activated protein kinase 2) (mapkap kinase 2) (mapkapk-2). [swissprot;acc:p49137]	1267	171.231	167.177	1.02425
map/microtubule affinity-regulating kinase 1. [refseq;acc:nm_018650]	922	236.741	245.547	1.0372
map/microtubule affinity-regulating kinase 2 isoform b; elkl motif kinase 1; elkl motif kinase. [refseq;acc:nm_004954]	923
maspin precursor (protease inhibitor 5). [swissprot;acc:p36952]	792	224.244	234.511	1.04578
mast cell carboxypeptidase a precursor (ec 3.4.17.1) (mc-cpa) (carboxypeptidase a3). [swissprot;acc:p15088]	508	177.698	190.24	1.07058
mawd binding protein (unknown protein 32 from 2d-page of liver tissue). [swissprot;acc:p30039]	2411	194.407	193.706	1.00362
max dimerization protein 3; likely ortholog of mouse max dimerization protein 3. [refseq;acc:nm_031300]	259	227.999	204.37	1.11562
max interacting protein 1 (mxi1 protein). [swissprot;acc:p50539]	256		204.357	1.11569
max protein. [swissprot;acc:p25912]	425	227.828	210.561	1.082
max-interacting transcriptional repressor mad4 (max-associated protein 4) (max dimerization protein 4). [swissprot;acc:q14582]	258	227.999	204.366	1.11564
mbd2 (methyl-cpg-binding protein)-interacting zinc finger protein. [refseq;acc:nm_015517]	2331	229.258	230.294	1.00452
mct-1 protein. [refseq;acc:nm_014060]	486	226.313	243.03	1.07387
megf10 protein. [refseq;acc:nm_032446]	1944	224.341	222.148	1.00987
megf11 protein. [refseq;acc:nm_032445]	1943	224.34	222.147

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.