Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1551 to 1600 of 8289 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1
Rank
description
Interaction Map
red
green
network_comparison
776 dj153g14.2 (possible ca binding protein similar to nefa) (fragment). [sptrembl;acc:q9ujn8] High confidence 225.996 215.535 1.04854
mad1-like 1; mad1 (mitotic arrest deficient, yeast, homolog)-like 1; mitotic-arrest deficient 1, yeast, homolog-like 1; tumor protein p53 inducible protein 9. [refseq;acc:nm_003550] Low confidence 208.017 202.601 1.02673
777 adapter-related protein complex 1 sigma 1c subunit (sigma-adaptin 1c) (adaptor protein complex ap-1 sigma-1c subunit) (golgi adaptor ha1/ap1 adaptin sigma-1c subunit) (clathrin assembly protein complex 1 sigma- 1c small chain) (sigma 1c subunit of ap-1 clathrin). [swissprot;acc:q96pc3] 204.807 199.484 1.02668
histone deacetylase 1 (hd1). [swissprot;acc:q13547] High confidence 225.989 215.53 1.04853
778 sorting nexin 6 (traf4-associated factor 2). [swissprot;acc:q9unh7] 209.191 219.332 1.04848
wd repeat domain 26. [refseq;acc:nm_025160] Low confidence 188.145 183.258 1.02667
779 abl-interactor 2; abl-interacting protein 1 (sh3-containing protein); abl binding protein 3; arg protein tyrosine kinase-binding protein; abl-interactor protein 2b; similar to spectrin sh3 domain binding protein 1. [refseq;acc:nm_005759] 202.48 197.229 1.02662
deoxycytidylate deaminase (ec 3.5.4.12) (dcmp deaminase). [swissprot;acc:p32321] High confidence 230.516 241.641 1.04826
780 dna-directed rna polymerase ii 14.4 kda polypeptide (ec 2.7.7.6) (rpb6) (rpb14.4) (rpabc2). [swissprot;acc:p41584] 232.762 243.933 1.04799
importin 9. [refseq;acc:nm_018085] Low confidence 204.192 198.902 1.0266
781 protein arginine n-methyltransferase (ec 2.1.1.-). [swissprot;acc:q9nvm4] 203.591 198.319 1.02658
ribosomal protein p0-like protein; 60s acidic ribosomal protein po; ribosomal protein, large, p0-like. [refseq;acc:nm_016183] High confidence 245.84 257.636 1.04798
782 pallidin; pallid (mouse) homolog, pallidin. [refseq;acc:nm_012388] Low confidence 203.591 198.319 1.02658
translin. [swissprot;acc:q15631] High confidence 224.385 235.131 1.04789
783 porphobilinogen deaminase (ec 4.3.1.8) (hydroxymethylbilane synthase) (hmbs) (pre-uroporphyrinogen synthase) (pbg-d). [swissprot;acc:p08397] Low confidence 204.238 198.951 1.02657
translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598] High confidence 224.385 235.131 1.04789
784 polyglutamine binding protein 1; nuclear protein containing ww domain 38 kd. [refseq;acc:nm_005710]
xpa-binding protein 2 (hcnp protein) (pp3898). [swissprot;acc:q9hcs7] Low confidence 201.338 196.126 1.02657
785 neuroepithelial cell transforming gene 1; guanine nucleotide regulatory protein (oncogene); rho guanine nucleotide exchange factor (gef) 8. [refseq;acc:nm_005863] High confidence 244.447 233.508 1.04685
spectrin sh3 domain binding protein 1; eps8 binding protein; interactor protein ablbp4; abl-interactor protein 1 long; nap1 binding protein. [refseq;acc:nm_005470] Low confidence 202.469 197.233 1.02655
786 f-box and leucine-rich repeat protein 11; f-box protein fbl11. [refseq;acc:nm_012308] 202.957 208.337 1.02651
rho guanine nucleotide exchange factor 3; rhogef protein; 59.8 kda protein; exchange factor found in platelets and leukemic and neuronal tissues, xpln. [refseq;acc:nm_019555] High confidence 244.447 233.508 1.04685
787 atpase, h+ transporting, lysosomal 42kda, v1 subunit c isoform 2; v-atpase c2 subunit. [refseq;acc:nm_144583] Low confidence 202.489 197.259 1.02651
down-regulated in metastasis. [refseq;acc:nm_014503] High confidence 244.447 233.508 1.04685
788 eukaryotic translation initiation factor 4 gamma, 3. [refseq;acc:nm_003760] Low confidence 200.788 195.605 1.0265
hira-interacting protein 5 (cgi-33). [swissprot;acc:q9ums0] High confidence 138.705 132.538 1.04653
789 40s ribosomal protein sa (p40) (34/67 kda laminin receptor) (colon carcinoma laminin-binding protein) (nem/1chd4) (multidrug resistance- associated protein mgr1-ag). [swissprot;acc:p08865] 224.244 234.511 1.04578
polypeptide n-acetylgalactosaminyltransferase 2; udp-galnac transferase 2. [refseq;acc:nm_004481] Low confidence 205.859 200.547 1.02649
790 40s ribosomal protein s21. [swissprot;acc:p35265] High confidence 224.244 234.511 1.04578
eukaryotic translation initiation factor 4 gamma (eif-4-gamma) (eif- 4g) (eif4g) (p220). [swissprot;acc:q04637] Low confidence 200.79 195.608 1.02649
791 cytoplasmic antiproteinase 3 (cap3) (cap-3) (protease inhibitor 9) (serpin b9). [swissprot;acc:p50453] High confidence 224.244 234.511 1.04578
similar to expressed sequence ai415388 (fragment). [sptrembl;acc:q8n428] Low confidence 205.859 200.547 1.02649
792 hiv-1 rev binding protein 2; rev interacting protein. [refseq;acc:nm_007043] 204.204 198.939 1.02647
maspin precursor (protease inhibitor 5). [swissprot;acc:p36952] High confidence 224.244 234.511 1.04578
793 bomapin (protease inhibitor 10) (serpin b10). [swissprot;acc:p48595]
similar to atp/gtp-binding protein. [sptrembl;acc:q8nem8] Low confidence 184.195 179.447 1.02646
794 plasminogen activator inhibitor-2 precursor (pai-2) (placental plasminogen activator inhibitor) (monocyte arg-serpin) (urokinase inhibitor). [swissprot;acc:p05120] High confidence 224.244 234.511 1.04578
trna (5-methylaminomethyl-2-thiouridylate)-methyltransferase (ec 2.1.1.61). [swissprot;acc:o75648] Low confidence 184.195 179.447 1.02646
795 calcium-dependent protease, small subunit (calpain regulatory subunit) (calcium-activated neutral proteinase) (canp). [swissprot;acc:p04632] 202.525 197.308 1.02644
serpin b11. [swissprot;acc:q96p15] High confidence 224.244 234.511 1.04578
796 grancalcin. [swissprot;acc:p28676] Low confidence 202.524 197.308 1.02644
placental thrombin inhibitor (cytoplasmic antiproteinase) (cap) (protease inhibitor 6) (pi-6). [swissprot;acc:p35237] High confidence 224.244 234.511 1.04578
797 asc-1 complex subunit p100. [refseq;acc:nm_032204] Low confidence 211.636 206.184 1.02644
cytoplasmic antiproteinase 2 (cap2) (cap-2) (protease inhibitor 8) (serpin b8). [swissprot;acc:p50452] High confidence 224.244 234.511 1.04578
798 leukocyte elastase inhibitor (lei) (monocyte/neutrophil elastase inhibitor) (m/nei) (ei). [swissprot;acc:p30740]
sorcin (22 kda protein) (cp-22) (v19). [swissprot;acc:p30626] Low confidence 202.524 197.308 1.02644
799 amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433] 201.294 196.11 1.02643
sequestosome 1; ubiquitin-binding protein p62; phosphotyrosine independent ligand for the lck sh2 domain p62. [refseq;acc:nm_003900] High confidence 221.965 212.404 1.04501
800 nonspecific lipid-transfer protein, mitochondrial precursor (nsl-tp) (sterol carrier protein 2) (scp-2) (sterol carrier protein x) (scp-x) (scpx). [swissprot;acc:p22307]
rp42 homolog; squamous cell carcinoma-related oncogene. [refseq;acc:nm_020640] Low confidence 202.755 197.536 1.02642

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/