MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	description	Value Type	Network Comparison Type	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1513 to 1562 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
Filtered  : 1
green  : 0
network_comparison  : 0

Rank	description	Value Type
3134	rab geranylgeranyltransferase alpha subunit (ec 2.5.1.-) (rab geranyl- geranyltransferase alpha subunit) (rab gg transferase alpha) (rab ggtase alpha). [swissprot;acc:q92696]	Measured
		Ranked
		Squared
		Rooted
3135	protein transport protein sec23a (sec23-related protein a). [swissprot;acc:q15436]	Measured
		Ranked
		Squared
		Rooted
3136	vaccinia related kinase 1; vaccinia-related kinase-1. [refseq;acc:nm_003384]	Measured
		Ranked
		Squared
		Rooted
3137	serine/threonine-protein kinase kkialre (ec 2.7.1.-) (cyclin-dependent kinase-like 1). [swissprot;acc:q00532]	Measured
		Ranked
		Squared
		Rooted
3138	hcdi protein. [refseq;acc:nm_020195]	Measured
		Ranked
		Squared
		Rooted
3139	bromodomain-containing protein 1 (br140-like protein). [swissprot;acc:o95696]	Measured
		Ranked
		Squared
		Rooted
3140	myosin heavy chain, nonmuscle type a (cellular myosin heavy chain, type a) (nonmuscle myosin heavy chain-a) (nmmhc-a). [swissprot;acc:p35579]	Measured
		Ranked
		Squared
		Rooted
3141	tubulin tyrosine ligase-like protein 1. [swissprot;acc:o95922]	Measured
		Ranked
		Squared
		Rooted
3142	protein kinase c and casein kinase substrate in neurons protein 2. [swissprot;acc:q9unf0]	Measured
		Ranked
		Squared
		Rooted
3143	prkca-binding protein (protein kinase c-alpha binding protein) (protein interacting with c kinase 1). [swissprot;acc:q9nrd5]	Measured
		Ranked
		Squared
		Rooted
3144	high mobility group protein 1-like 10 (hmg-1l10). [swissprot;acc:q9ugv6]	Measured
		Ranked
		Squared
		Rooted
3145	beta-ureidopropionase (ec 3.5.1.6) (beta-alanine synthase) (n-carbamoyl-beta-alanine amidohydrolase) (bup-1). [swissprot;acc:q9ubr1]	Measured
		Ranked
		Squared
		Rooted
3146	putative nadh oxidoreductase complex i subunit homolog. [sptrembl;acc:q96q80]	Measured
		Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.