Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Value Type description green Rank Network Comparison Type red Interaction Map network_comparison Filtered
Results: HTML CSV LaTeX Showing element 151 to 200 of 2061 in total
Value Type  : Measured
green  : 0
Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Filtered  : 1
description
Rank
Interaction Map
glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075] 2957 High confidence
glycerol-3-phosphate acyltransferase, mitochondrial precursor (ec 2.3.1.15) (gpat). [swissprot;acc:q9hcl2] 3033
glycine receptor alpha-1 chain precursor (glycine receptor 48 kda subunit) (strychnine binding subunit). [swissprot;acc:p23415] 2919
glycine receptor alpha-2 chain precursor. [swissprot;acc:p23416] 3121
glycine receptor alpha-3 chain precursor. [swissprot;acc:o75311] 2920
glycine receptor beta chain precursor (glycine receptor 58 kda subunit). [swissprot;acc:p48167] 3083
gpi transamidase component pig-s (phosphatidylinositol-glycan biosynthesis, class s protein). [swissprot;acc:q96s52] 3165
guanine nucleotide exchange factor mss4 (rab interacting factor). [swissprot;acc:p47224] 2777
guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4] 2761
h2a histone family, member j isoform 1. [refseq;acc:nm_018267] 3077
hcdi protein. [refseq;acc:nm_020195] 3138
headcase homolog; hhdc for homolog of drosophila headcase. [refseq;acc:nm_016217] 3068
heat-shock 20 kda like-protein p20. [swissprot;acc:o14558] 3225
heat-shock protein, beta-2 (hspb2) (dmpk-binding protein) (mkbp). [swissprot;acc:q16082] 2824
high mobility group protein 1 (hmg-1). [swissprot;acc:p09429] 2989
high mobility group protein 1-like 10 (hmg-1l10). [swissprot;acc:q9ugv6] 3144
high mobility group protein 2 (hmg-2). [swissprot;acc:p26583] 2856
high mobility group protein 4 (hmg-4) (high mobility group protein 2a) (hmg-2a). [swissprot;acc:o15347] 3203
high mobility group protein 4-like (hmg-4l). [swissprot;acc:q9uj13] 2787
high-affinity cgmp-specific 3',5'-cyclic phosphodiesterase 9a (ec 3.1.4.17). [swissprot;acc:o76083] 2876
high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9] 2863
histone deacetylase 3 (hd3) (rpd3-2). [swissprot;acc:o15379] 2813
5022 Low confidence
histone deacetylase 6 (hd6). [swissprot;acc:q9ubn7] 3152 High confidence
histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001] 2784
histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261] 2767
histone h2a.e (h2a/e). [swissprot;acc:q99878] 2765
histone h2a.q (h2a/q) (h2a-gl101) (fragment). [swissprot;acc:q16777] 2769
histone h2a.x (h2a/x). [swissprot;acc:p16104] 2768
histone h2a; h2a histone family, member r. [refseq;acc:nm_170745] 2852
hmg2 like. [refseq;acc:nm_145205] 2799
homeobox protein nkx-6.1. [swissprot;acc:p78426] 2859
homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (methyl methanesulfonate (mmf)-inducible fragment protein 1). [swissprot;acc:q15011] 3196
5060 Low confidence
homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099] 3053 High confidence
5047 Low confidence
hormone sensitive lipase (ec 3.1.1.-) (hsl). [swissprot;acc:q05469] 3172 High confidence
importin 9. [refseq;acc:nm_018085] 2860
importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292] 2780
inositol polyphosphate-5-phosphatase; phosphatidylinositol polyphosphate 5-phosphatase type iv; phosphatidylinositol (4,5) bisphosphate 5-phosphatase. [refseq;acc:nm_019892] 2912
integrin alpha-3 precursor (galactoprotein b3) (gapb3) (vla-3 alpha chain) (cd49c). [swissprot;acc:p26006] 3224
integrin alpha-6 precursor (vla-6) (cd49f). [swissprot;acc:p23229] 3158
integrin alpha-7 precursor. [swissprot;acc:q13683] 2978
integrin beta-1 precursor (fibronectin receptor beta subunit) (cd29 antigen) (integrin vla-4 beta subunit). [swissprot;acc:p05556] 2905
integrin beta-2 precursor (cell surface adhesion glycoproteins lfa- 1/cr3/p150,95 beta-subunit) (cd18) (complement receptor c3 beta- subunit). [swissprot;acc:p05107] 2873
integrin beta-3 precursor (platelet membrane glycoprotein iiia) (gpiiia) (cd61 antigen). [swissprot;acc:p05106] 3195
integrin beta-7 precursor. [swissprot;acc:p26010] 2951
interleukin enhancer binding factor 2; nuclear factor of activated t-cells, 45-kda. [refseq;acc:nm_004515] 2930
jerky protein homolog like (hhmjg). [swissprot;acc:q9y4a0] 2775
5020 Low confidence

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/