Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 2030 to 2079 of 8289 in total
Value Type  : Measured
Network Comparison Type  : Divided
Filtered  : 1
Rank
description
Interaction Map
red
green
network_comparison
1015 protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22] Low confidence 7877.17 8176.48 1.038
1016 alpha glucosidase ii alpha subunit; likely ortholog of mouse g2an alpha glucosidase 2, alpha neutral subunit. [refseq;acc:nm_014610] 8456.9 8778.27
peroxisomal targeting signal 1 receptor (peroxismore receptor 1) (peroxisomal c-terminal targeting signal import receptor) (pts1-bp) (peroxin-5) (pts1 receptor). [swissprot;acc:p50542] High confidence 5791.82 6340.86 1.0948
1017 hairy/enhancer-of-split related with yrpw motif 2; gridlock; hes-related repressor protein 1. [refseq;acc:nm_012259]
lysine-deficient protein kinase 2; mitogen-activated protein kinase kinase kinase; serologically defined colon cancer antigen 43. [refseq;acc:nm_006648] Low confidence 7769.69 8064.74 1.03797
1018 protein kinase, lysine deficient 4; putative protein kinase wnk4. [refseq;acc:nm_032387]
transcription factor hes-1 (hairy and enhancer of split 1) (hairy- like) (hhl) (hairy homolog). [swissprot;acc:q14469] High confidence 5791.82 6340.86 1.0948
1019 delta3,5-delta2,4-dienoyl-coa isomerase, mitochondrial precursor (ec 5.3.3.-). [swissprot;acc:q13011]
protein kinase, lysine deficient 3. [refseq;acc:nm_020922] Low confidence 7769.69 8064.74 1.03797
1020 actin-binding lim protein 1 isoform a; lim actin-binding protein 1; limatin; actin-binding lim protein. [refseq;acc:nm_002313] High confidence 5791.82 6340.86 1.0948
protein kinase, lysine deficient 1; kinase deficient protein. [refseq;acc:nm_018979] Low confidence 7769.69 8064.74 1.03797
1021 exonuclease nef-sp. [refseq;acc:nm_030941]
synapsin i (brain protein 4.1). [swissprot;acc:p17600] High confidence 5791.82 6340.86 1.0948
1022 mitochondrial import inner membrane translocase subunit tim13 b. [swissprot;acc:q9y5l4] Low confidence 7877.5 8176.51 1.03796
protein kinase clk2 (ec 2.7.1.-) (cdc-like kinase 2). [swissprot;acc:p49760] High confidence 6435.94 7045.75 1.09475
1023 adapter-related protein complex 2 beta 1 subunit (beta-adaptin) (plasma membrane adaptor ha2/ap2 adaptin beta subunit) (clathrin assembly protein complex 2 beta large chain) (ap105b). [swissprot;acc:p21851] Low confidence 7716.88 8009.78 1.03796
protein kinase clk3 (ec 2.7.1.-) (cdc-like kinase 3). [swissprot;acc:p49761] High confidence 6435.02 7044.65 1.09474
1024 26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998] Low confidence 8385.76 8703.92 1.03794
cysteine-rich protein 1 (cysteine-rich intestinal protein) (crip) (cysteine-rich heart protein) (hcrhp). [swissprot;acc:p50238] High confidence 5706.5 6245.55 1.09446
1025 phosphomannomutase 2 (ec 5.4.2.8) (pmm 2). [swissprot;acc:o15305] 5511.96 6031.95 1.09434
striated muscle activator of rho-dependent signaling. [refseq;acc:nm_139166] Low confidence 7445.04 7727.46 1.03793
1026 guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086] 7728.58 8021.71
phosphomannomutase 1 (ec 5.4.2.8) (pmm 1) (pmmh-22). [swissprot;acc:q92871] High confidence 5509.89 6029.29 1.09427
1027 protein arginine n-methyltransferase 1 (ec 2.1.1.-) (interferon receptor 1-bound protein 4). [swissprot;acc:q99873] Low confidence 7877.81 8176.55 1.03792
s-adenosylmethionine synthetase gamma form (ec 2.5.1.6) (methionine adenosyltransferase) (adomet synthetase) (mat-ii). [swissprot;acc:p31153] High confidence 6123.15 6700.05 1.09422
1028 guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488] Low confidence 7727.97 8020.98 1.03792
nicotinate-nucleotide pyrophosphorylase [carboxylating] (ec 2.4.2.19) (quinolinate phosphoribosyltransferase [decarboxylating]) (qaprtase) (qprtase). [swissprot;acc:q15274] High confidence 5704 6241.36 1.09421
1029 beta-catenin (pro2286). [swissprot;acc:p35222] 5635.26 6166.09 1.0942
inositol-1(or 4)-monophosphatase 2 (ec 3.1.3.25) (impase 2) (imp 2) (inositol monophosphatase 2) (myo-inositol monophosphatase a2). [swissprot;acc:o14732] Low confidence 7809.04 8105.05 1.03791
1030 casein kinase i, epsilon isoform (ec 2.7.1.-) (cki-epsilon) (ckie). [swissprot;acc:p49674] High confidence 5048.33 5523.85 1.09419
guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [swissprot;acc:p19087] Low confidence 7727.68 8020.64 1.03791
1031 guanine nucleotide-binding protein g(i), alpha-2 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04899] 7724.11 8016.44 1.03785
membrane protein expressed in epithelial-like lung adenocarcinoma. [refseq;acc:nm_024792] High confidence 6136.99 6714.98 1.09418
1032 2-oxoglutarate dehydrogenase e1 component, mitochondrial precursor (ec 1.2.4.2) (alpha-ketoglutarate dehydrogenase). [swissprot;acc:q02218] Low confidence 8029.13 8332.97 1.03784
ran binding protein 11. [refseq;acc:nm_016338] High confidence 6138.91 6717.05 1.09418
1033 fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757] 6080.91 6653.52 1.09417
inosine-5'-monophosphate dehydrogenase 2 (ec 1.1.1.205) (imp dehydrogenase 2) (impdh-ii) (impd 2). [swissprot;acc:p12268] Low confidence 8176.71 8486.04 1.03783
1034 s-adenosylmethionine synthetase alpha and beta forms (ec 2.5.1.6) (methionine adenosyltransferase) (adomet synthetase) (mat-i/iii). [swissprot;acc:q00266] High confidence 6152.88 6732.12 1.09414
u5 snrnp-associated 102 kda protein (u5-102 kda protein). [swissprot;acc:o94906] Low confidence 7721.24 8013.26 1.03782
1035 casein kinase i, delta isoform (ec 2.7.1.-) (cki-delta) (ckid). [swissprot;acc:p48730] High confidence 5054.73 5530.23 1.09407
vesicle transport-related protein isoform a; vesicle transport-related protein. [refseq;acc:nm_016106] Low confidence 8054.13 8358.75 1.03782
1036 dna polymerase gamma subunit 1 (ec 2.7.7.7) (mitochondrial dna polymerase catalytic subunit) (polg-alpha). [swissprot;acc:p54098] 8023.84 8327.22 1.03781
fructose-1,6-bisphosphatase (ec 3.1.3.11) (d-fructose-1,6-bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:p09467] High confidence 6077.65 6649.22 1.09404
1037 inositol-1(or 4)-monophosphatase (ec 3.1.3.25) (impase) (imp) (inositol monophosphatase) (lithium-sensitive myo-inositol monophosphatase a1). [swissprot;acc:p29218] Low confidence 7811.62 8106.99 1.03781
monoglyceride lipase; lysophospholipase-like. [refseq;acc:nm_007283] High confidence 6544.26 7159.43 1.094
1038 guanine nucleotide-binding protein g(i), alpha-1 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04898] Low confidence 7722.06 8014.04 1.03781
myb proto-oncogene protein (c-myb). [swissprot;acc:p10242] High confidence 5417.95 5924.41 1.09348
1039 guanine nucleotide-binding protein g(k), alpha subunit (g(i) alpha-3). [swissprot;acc:p08754] Low confidence 7722.06 8014.04 1.03781
myb-related protein b (b-myb). [swissprot;acc:p10244] High confidence 5418.92 5923.09 1.09304
1040 inosine-5'-monophosphate dehydrogenase 1 (ec 1.1.1.205) (imp dehydrogenase 1) (impdh-i) (impd 1). [swissprot;acc:p20839] Low confidence 8176.07 8485.02 1.03779

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/