Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1325 to 1374 of 6456 in total
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1
Rank
description
Network Comparison Type
red
green
network_comparison
663 isocitrate dehydrogenase [nadp], mitochondrial precursor (ec 1.1.1.42) (oxalosuccinate decarboxylase) (idh) (nadp+-specific icdh) (idp) (icd-m). [swissprot;acc:p48735] Subtracted 7937.72 8646.38 708.66
tubby protein homolog. [swissprot;acc:p50607] Divided 6374.65 7145.59 1.12094
664 pms1 protein homolog 2 (dna mismatch repair protein pms2). [swissprot;acc:p54278] Subtracted 6231.31 6933.9 702.59
protein kinase c, iota type (ec 2.7.1.37) (npkc-iota) (atypical protein kinase c-lamda/iota) (apkc-lambda/iota). [swissprot;acc:p41743] Divided 6374.65 7145.59 1.12094
665 lupus la protein (sjogren syndrome type b antigen) (ss-b) (la ribonucleoprotein) (la autoantigen). [swissprot;acc:p05455] Subtracted 4108.15 4808.93 700.78
numb protein homolog (h-numb) (protein s171). [swissprot;acc:p49757] Divided 6374.65 7145.59 1.12094
666 epididymal secretory protein e1 precursor (niemann-pick disease type c2 protein) (epi-1) (he1) (epididymal secretory protein 14.6) (esp14.6). [swissprot;acc:q15668] Subtracted 6781.05 7480.15 699.1
tbc1 domain family member 5. [swissprot;acc:q92609] Divided 6374.65 7145.59 1.12094
667 coatomer beta' subunit (beta'-coat protein) (beta'-cop) (p102). [swissprot;acc:p35606] Subtracted 10075.5 9377.75 697.75
tubby related protein 1 (tubby-like protein 1). [swissprot;acc:o00294] Divided 6374.65 7145.59 1.12094
668 coatomer gamma subunit (gamma-coat protein) (gamma-cop). [swissprot;acc:q9y678] Subtracted 10075.5 9377.75 697.75
vacuolar protein sorting 29 (vesicle protein sorting 29) (hvps29) (mds007) (pep11) (dc7/dc15). [swissprot;acc:q9ubq0] Divided 6374.65 7145.59 1.12094
669 coatomer zeta-1 subunit (zeta-1 coat protein) (zeta-1 cop) (cgi-120) (hspc181). [swissprot;acc:q9y3c3] Subtracted 10075.5 9377.75 697.75
numb-like protein (numb-r). [swissprot;acc:q9y6r0] Divided 6374.65 7145.59 1.12094
670 coatomer delta subunit (delta-coat protein) (delta-cop) (archain). [swissprot;acc:p48444] Subtracted 10075.5 9377.75 697.75
tubby related protein 3 (tubby-like protein 3). [swissprot;acc:o75386] Divided 6374.65 7145.59 1.12094
671 peptidyl-prolyl cis-trans isomerase e (ec 5.2.1.8) (ppiase e) (rotamase e) (cyclophilin e) (cyclophilin 33). [swissprot;acc:q9unp9] Subtracted 10075.5 9377.75 697.75
vacuolar protein sorting 35 (vesicle protein sorting 35) (hvps35) (maternal-embryonic 3). [swissprot;acc:q96qk1] Divided 6374.65 7145.59 1.12094
672 coatomer zeta-2 subunit (zeta-2 coat protein) (zeta-2 cop). [swissprot;acc:q9p299] Subtracted 10075.5 9377.75 697.75
protein kinase c, zeta type (ec 2.7.1.37) (npkc-zeta). [swissprot;acc:q05513] Divided 6374.65 7145.59 1.12094
673 fibulin-1 precursor. [swissprot;acc:p23142] Subtracted 8550.79 9248.06 697.27
transcription factor btf3 (rna polymerase b transcription factor 3). [swissprot;acc:p20290] Divided 6933.17 7766.54 1.1202
674 hcv ns3-transactivated protein 1. [refseq;acc:nm_019048] Subtracted 6000.23 6696.89 696.66
sprouty homolog 4 (spry-4). [swissprot;acc:q9c004] Divided 5549.2 6215.42 1.12006
675 sprouty homolog 3 (spry-3). [swissprot;acc:o43610]
vacuolar atp synthase catalytic subunit a, ubiquitous isoform (ec 3.6.3.14) (v-atpase a subunit 1) (vacuolar proton pump alpha subunit 1) (v-atpase 69 kda subunit 1) (isoform va68). [swissprot;acc:p38606] Subtracted 6000.23 6696.89 696.66
676 asparagine synthetase [glutamine-hydrolyzing] (ec 6.3.5.4) (glutamine- dependent asparagine synthetase) (ts11 cell cycle control protein). [swissprot;acc:p08243]
sprouty homolog 1 (spry-1) (fragment). [swissprot;acc:o43609] Divided 5549.2 6215.42 1.12006
677 dna polymerase epsilon, catalytic subunit a (ec 2.7.7.7) (dna polymerase ii subunit a). [swissprot;acc:q07864] Subtracted 4024.4 4719.35 694.95
sprouty homolog 2 (spry-2). [swissprot;acc:o43597] Divided 5549.2 6215.42 1.12006
678 cytoplasmic protein nck1 (nck adaptor protein 1) (sh2/sh3 adaptor protein nck-alpha). [swissprot;acc:p16333] Subtracted 6784.67 7475.48 690.81
transcription factor btf3 homolog 3. [swissprot;acc:q13892] Divided 6938.22 7770.65 1.11998
679 adenylosuccinate synthase-like 1. [refseq;acc:nm_152328] 6503.1 7282.94 1.11992
n-acetylgalactosamine kinase (ec 2.7.1.-) (galnac kinase) (galactokinase 2). [swissprot;acc:q01415] Subtracted 4910.6 5600.61 690.01
680 adenylosuccinate synthetase (ec 6.3.4.4) (imp--aspartate ligase) (adss) (ampsase). [swissprot;acc:p30520] Divided 6503.03 7282.5 1.11986
galactose-1-phosphate uridylyltransferase (ec 2.7.7.12) (gal-1-p uridylyltransferase) (udp-glucose--hexose-1-phosphate uridylyltransferase). [swissprot;acc:p07902] Subtracted 4910.6 5600.61 690.01
681 ribosomal protein l24-like; 60s ribosomal protein l30 isolog; my024 protein; homolog of yeast ribosomal like protein 24. [refseq;acc:nm_016304] Divided 7170.83 8029.64 1.11976
udp-glucose 4-epimerase (ec 5.1.3.2) (galactowaldenase) (udp- galactose 4-epimerase). [swissprot;acc:q14376] Subtracted 4910.6 5600.61 690.01
682 methionyl-trna synthetase (ec 6.1.1.10) (methionine--trna ligase) (metrs). [swissprot;acc:p56192] 5560.06 6248.27 688.21
syntaxin 12. [refseq;acc:nm_177424] Divided 5552.92 6217.59 1.1197
683 dna polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4). [swissprot;acc:q9nr33] Subtracted 3751.3 4431.34 680.04
sh3-containing grb2-like protein 1 (sh3 domain protein 2b) (extra eleven-nineteen leukemia fusion gene) (een) (een fusion partner of mll). [swissprot;acc:q99961] Divided 7139.5 7994.06 1.11969
684 eukaryotic translation initiation factor 3 subunit 9 (eif-3 eta) (eif3 p116) (eif3 p110) (eif3b). [swissprot;acc:p55884] 4359.82 4880.99 1.11954
u2 small nuclear ribonucleoprotein auxiliary factor 35 kda subunit related-protein 1. [swissprot;acc:q15695] Subtracted 5575.18 6254.85 679.67
685 metaxin 1. [swissprot;acc:q13505] Divided 9327.58 10442.2 1.1195
step ii splicing factor slu7. [refseq;acc:nm_006425] Subtracted 5575.18 6254.85 679.67
686 5'-amp-activated protein kinase, gamma-1 subunit (ampk gamma-1 chain) (ampkg). [swissprot;acc:p54619] Divided 6920.69 7747.63 1.11949
uba/ubx 33.3 kda protein. [swissprot;acc:q04323] Subtracted 6562.98 7242.37 679.39
687 5'-amp-activated protein kinase, catalytic alpha-2 chain (ec 2.7.1.-) (ampk alpha-2 chain). [swissprot;acc:p54646] Divided 6920.71 7747.65 1.11949
ero1-like. [refseq;acc:nm_014584] Subtracted 6562.98 7242.37 679.39

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/