Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered green Value Type Rank Gene Interaction Map network_comparison description red Network Comparison Type
Results: HTML CSV LaTeX Showing element 951 to 1000 of 77072 in total
Filtered  : 0
green
Value Type
Rank
Interaction Map
network_comparison
description
red
Network Comparison Type
12.1701 Rooted 432 High confidence 1.02772 signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556] 12.5074 Divided
455 0.3373 Subtracted
12.1722 86 1.3321 mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476] 9.13761 Divided
89 Low confidence
170 High confidence 3.03459 Subtracted
272 Low confidence
12.2043 165 1.15882 transcription factor bteb4 (basic transcription element binding- protein 4) (bte-binding protein 4) (krueppel-like factor 16) (novel sp1-like zinc finger transcription factor 2) (transcription factor nslp2). [swissprot;acc:q9bxk1] 10.5317 Divided
432 1.6726 Subtracted
12.2755 570 1.0411 amiloride-sensitive sodium channel gamma-subunit (epithelial na+ channel gamma subunit) (gamma enac) (nonvoltage-gated sodium channel 1 gamma subunit) (scneg) (gamma nach). [swissprot;acc:p51170] 11.7909 Divided
711 0.4846 Subtracted
12.2759 569 1.04115 amiloride-sensitive cation channel 3 isoform a; testis sodium channel 1; proton-gated cation channel subunit; modulatory subunit of asic2a; amiloride-sensitive cation channel 3, testis. [refseq;acc:nm_004769] 11.7907 Divided
710 0.4852 Subtracted
12.2882 51 High confidence 1.58009 nanos (fragment). [sptrembl;acc:q8wy41] 19.4165 Divided
57 7.1283 Subtracted
60 1.44818 selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611] 8.48528 Divided
63 Low confidence
144 High confidence 3.80292 Subtracted
225 Low confidence
12.2937 Squared 120 High confidence 1.90407 syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623] 6.45653 Divided
406 5.83717 Subtracted
12.3076 Rooted 106 Low confidence 1.27875 solute carrier family 26, member 11. [refseq;acc:nm_173626] 15.7383 Divided
244 3.4307 Subtracted
12.3132 80 1.35362 alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [swissprot;acc:q9nvd7] 16.6674 Divided
189 4.3542 Subtracted
12.3994 498 1.05566 amiloride-sensitive sodium channel delta-subunit (epithelial na+ channel delta subunit) (delta enac) (nonvoltage-gated sodium channel 1 delta subunit) (scned) (delta nach). [swissprot;acc:p51172] 11.7456 Divided
660 0.6538 Subtracted
12.4394 372 High confidence 1.04116 secreted modular calcium-binding protein 1. [refseq;acc:nm_022137] 11.9476 Divided
432 0.4918 Subtracted
568 Low confidence 1.04116 Divided
708 0.4918 Subtracted
12.4629 487 High confidence 1.0032 pepsin a precursor (ec 3.4.23.1). [swissprot;acc:p00790] 12.5028 Divided
488 0.0399 Subtracted
12.49 22 3.94968 succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor (cybs) (succinate-ubiquinone reductase membrane anchor subunit) (qps2) (cii-4) (succinate dehydrogenase complex subunit d) (succinate-ubiquinone oxidoreductase cytochrome b small subunit). [swissprot;acc:o14521] 3.16228 Divided
34 9.32772 Subtracted
12.5026 285 1.08467 40s ribosomal protein s28. [swissprot;acc:p25112] 13.5612 Divided
368 1.0586 Subtracted
12.5624 Squared 41 7.83299 dystrophin. [swissprot;acc:p11532] 98.4011 Divided
290 85.8387 Subtracted
12.5698 Rooted 17 Low confidence 2.29492 ptd016 protein. [refseq;acc:nm_016125] 5.47723 Divided
30 High confidence
Low confidence 7.09257 Subtracted
58 High confidence
12.6095 63 1.43581 dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2] 18.1049 Divided
85 5.4954 Subtracted
12.6188 Squared 99 Low confidence 2.13426 zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754] 26.9318 Divided
744 14.313 Subtracted
12.6735 Rooted 221 1.119 alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279] 14.1816 Divided
466 1.5081 Subtracted
12.7302 Squared 101 2.12849 b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2] 27.0961 Divided
743 14.3659 Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/