Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Value Type Rank Network Comparison Type Interaction Map description Filtered red network_comparison green
Results: HTML CSV LaTeX Showing element 1058 to 1107 of 3228 in total 
Value Type	Measured
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	red	network_comparison	green	
1058	scy1-like 1; telomerase regulation-associated protein; ht019 protein; telomerase regulation-associated protein; n-terminal kinase-like protein; teratoma-associated tyrosine kinase; n-terminal kinase-like. [source:refseq;acc:nm_020680]	5412.23	1.0926	5913.4	
1059	tubulin-specific chaperone c (tubulin-folding cofactor c) (cfc). [source:swissprot;acc:q15814]	5719.01	1.0926	6248.6	
1060	putative acyl-coa thioester hydrolase cgi-16 (ec 3.1.2.-). [source:swissprot;acc:q9y305]	5719.01	1.0926	6248.6	
1061	nuclear pore complex protein nup98 (nucleoporin nup98) (98 kda nucleoporin). [source:swissprot;acc:p52948]	5412.23	1.0926	5913.4	
1062	ammecr1 protein. [source:refseq;acc:nm_015365]	5412.23	1.0926	5913.4	
1063	mrna-associated protein mrnp 41 (rae1 protein homolog). [source:swissprot;acc:p78406]	5412.23	1.0926	5913.4	
1064	dead-box protein. [source:refseq;acc:nm_018665]	5719.01	1.0926	6248.6	
1065	dna-(apurinic or apyrimidinic site) lyase (ec 4.2.99.18) (ap endonuclease 1) (apex nuclease) (apen) (ref-1 protein). [source:swissprot;acc:p27695]	6393.81	1.09245	6984.94	
1066	leucyl-trna synthetase. [source:refseq;acc:nm_020117]	5417.06	1.09244	5917.79	
1067	probable leucyl-trna synthetase, mitochondrial precursor (ec 6.1.1.4) (leucine--trna ligase) (leurs). [source:swissprot;acc:q15031]	5417.07	1.09243	5917.79	
1068	exocyst complex component sec15a. [source:swissprot;acc:q8tag9]	6201.54	1.09237	6774.35	
1069	elongation factor 2 (ef-2). [source:swissprot;acc:p13639]	5494.73	1.09215	6001.08	
1070	metabotropic glutamate receptor 2 precursor (mglur2). [source:swissprot;acc:q14416]	5494.73	1.09215	6001.08	
1071	metabotropic glutamate receptor 3 precursor (mglur3). [source:swissprot;acc:q14832]	5494.73	1.09215	6001.08	
1072	prefoldin subunit 3 (von hippel-lindau binding protein 1) (vhl binding protein-1) (vbp-1) (hibbj46). [source:swissprot;acc:q15765]	5207.39	1.09214	5687.2	
1073	prefoldin subunit 2 (hspc231). [source:swissprot;acc:q9uhv9]	5207.39	1.09214	5687.2	
1074	uxt protein (ubiquitously expressed transcript protein) (hspc024). [source:swissprot;acc:q9ubk9]	5207.39	1.09214	5687.2	
1075	phosphatidate cytidylyltransferase 1 (ec 2.7.7.41) (cdp-diglyceride synthetase 1) (cdp-diglyceride pyrophosphorylase 1) (cdp- diacylglycerol synthase 1) (cds 1) (ctp:phosphatidate cytidylyltransferase 1) (cdp-dag synthase 1) (cdp-dg synthetase 1). [source:swissprot;acc:q92903]	6441.56	1.09211	7034.86	
1076	solute carrier family 13, member 4 (na+/sulfate cotransporter sut-1). [source:swissprot;acc:q9ukg4]	6439.63	1.09202	7032.19	
1077	solute carrier family 13, member 3 (sodium-dependent high-affinity dicarboxylate transporter 2) (na(+)/dicarboxylate cotransporter 3) (nadc-3) (hnadc3). [source:swissprot;acc:q8wwt9]	6439.66	1.09202	7032.22	
1078	solute carrier family 13, member 1 (renal sodium/sulfate cotransporter) (na(+)/sulfate cotransporter) (hnasi-1). [source:swissprot;acc:q9bzw2]	6439.63	1.09202	7032.19	
1079	solute carrier family 13, member 2 (renal sodium/dicarboxylate cotransporter) (na(+)/dicarboxylate cotransporter 1) (nadc-1). [source:swissprot;acc:q13183]	6439.66	1.09202	7032.22	
1080	secretory carrier-associated membrane protein 2. [source:swissprot;acc:o15127]	6439.3	1.092	7031.73	
1081	secretory carrier-associated membrane protein 3. [source:swissprot;acc:o14828]	6439.3	1.092	7031.73	
1082	secretory carrier-associated membrane protein 1. [source:swissprot;acc:o15126]	6439.35	1.092	7031.8	
1083	exocyst complex component sec15b. [source:swissprot;acc:q9y2d4]	6213.51	1.09198	6785.04	
1084	phosphatidate cytidylyltransferase 2 (ec 2.7.7.41) (cdp-diglyceride synthetase 2) (cdp-diglyceride pyrophosphorylase 2) (cdp- diacylglycerol synthase 2) (cds 2) (ctp:phosphatidate cytidylyltransferase 2) (cdp-dag synthase 2) (cdp-dg synthetase 2). [source:swissprot;acc:o95674]	6437.49	1.09192	7029.22	
1085	glycerol-3-phosphate transporter (g-3-p transporter) (g-3-p permease). [source:swissprot;acc:p57057]	6520.28	1.09187	7119.28	
1086	proline oxidase, mitochondrial precursor (ec 1.5.3.-) (proline dehydrogenase). [source:swissprot;acc:o43272]	6520.28	1.09187	7119.28	
1087	junction plakoglobin (desmoplakin iii). [source:swissprot;acc:p14923]	5732.73	1.09139	6256.63	
1088	tax interaction protein 1. [source:refseq;acc:nm_014604]	5732.73	1.09139	6256.63	
1089	serine--pyruvate aminotransferase (ec 2.6.1.51) (spt) (alanine-- glyoxylate aminotransferase) (ec 2.6.1.44) (agt). [source:swissprot;acc:p21549]	6390.28	1.0912	6973.08	
1090	interleukin enhancer-binding factor 1 (cellular transcription factor ilf-1). [source:swissprot;acc:q01167]	5651.07	1.09086	6164.55	
1091	polyadenylate-binding protein 3 (poly(a)-binding protein 3) (pabp 3) (testis-specific poly(a)-binding protein). [source:swissprot;acc:q9h361]	5791.05	1.09075	6316.61	
1092	hskin17 protein. [source:refseq;acc:nm_012311]	5791.05	1.09075	6316.61	
1093	carnitine o-acetyltransferase (ec 2.3.1.7) (carnitine acetylase) (cat). [source:swissprot;acc:p43155]	5791.05	1.09075	6316.61	
1094	polyadenylate-binding protein 4 (poly(a)-binding protein 4) (pabp 4) (inducible poly(a)-binding protein) (ipabp) (activated-platelet protein-1) (app-1). [source:swissprot;acc:q13310]	5791.05	1.09075	6316.61	
1095	polyadenylate-binding protein 1 (poly(a)-binding protein 1) (pabp 1). [source:swissprot;acc:p11940]	5791.05	1.09075	6316.61	
1096	kinesin protein. [source:refseq;acc:nm_032559]	5356.23	1.09072	5842.15	
1097	homolog of yeast maf1. [source:refseq;acc:nm_032272]	6133.83	1.0907	6690.18	
1098	tumor differentially expressed protein 2. [source:refseq;acc:nm_178865]	6133.83	1.0907	6690.18	
1099	tumor differentially expressed protein 1 (transmembrane protein sbbi99). [source:swissprot;acc:q13530]	6133.83	1.0907	6690.18	
1100	tumor differentially expressed 1 protein like. [source:swissprot;acc:q9nrx5]	6133.83	1.0907	6690.18	
1101	d-3-phosphoglycerate dehydrogenase (ec 1.1.1.95) (3-pgdh). [source:swissprot;acc:o43175]	6133.83	1.0907	6690.18	
1102	phenylalanyl-trna synthetase beta chain (ec 6.1.1.20) (phenylalanine-- trna ligase beta chain) (phers) (hspc173). [source:swissprot;acc:q9nsd9]	5462.88	1.09066	5958.12	
1103	ny-ren-62 antigen (fragment). [source:sptrembl;acc:q9y590]	5358.18	1.09062	5843.73	
1104	kinesin-like protein kif2 (kinesin-2) (hk2). [source:swissprot;acc:o00139]	5359.72	1.09054	5844.97	
1105	synaptotagmin xii (sytxii). [source:swissprot;acc:q8iv01]	5460.49	1.09049	5954.62	
1106	peptide methionine sulfoxide reductase (ec 1.8.4.6) (protein- methionine-s-oxide reductase) (peptide met(o) reductase). [source:swissprot;acc:q9uj68]	5489.99	1.09046	5986.63	
1107	phosphoserine aminotransferase (ec 2.6.1.52) (psat). [source:swissprot;acc:q9y617]	5489.99	1.09046	5986.63	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/