Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene Network Comparison Type Hugo Value Type description Interaction Map Filtered red network_comparison green
Results: HTML CSV LaTeX Showing element 44 to 93 of 1892 in total
Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0
Rank
Hugo
Value Type
description
2766 SS18L1 Rooted ss18-like protein 1 (syt homolog-1). [swissprot;acc:o75177]
2767 no value Measured histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
Ranked
Squared
Rooted
2768 HIST2H2AB Measured histone h2a.x (h2a/x). [swissprot;acc:p16104]
Ranked
Squared
Rooted
2769 HIST2H2AC Measured histone h2a.q (h2a/q) (h2a-gl101) (fragment). [swissprot;acc:q16777]
Ranked
Squared
Rooted
2770 NIPSNAP1 Measured nipsnap1 protein. [swissprot;acc:q9bpw8]
Ranked
Squared
Rooted
2771 TBX1 Measured t-box transcription factor tbx1 (t-box protein 1) (testis-specific t-box protein). [swissprot;acc:o43435]
Ranked
Squared
Rooted
2772 NUDT14 Measured uridine diphosphate glucose pyrophosphatase. [refseq;acc:nm_177533]
Ranked
Squared
Rooted
2773 BMP8A Measured bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820]
Ranked
Squared
Rooted
2774 C3orf37 Measured dc12 protein. [refseq;acc:nm_020187]
Ranked
Squared
Rooted
2775 JRKL Measured jerky protein homolog like (hhmjg). [swissprot;acc:q9y4a0]
Ranked
Squared
Rooted
2776 BCOR Measured bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]
Ranked
Squared
Rooted
2777 RABIF Measured guanine nucleotide exchange factor mss4 (rab interacting factor). [swissprot;acc:p47224]
Ranked
Squared
Rooted
2778 MAFA Measured transcription factor mammalian mafa (pancreatic beta-cell specific transcriptional activator). [sptrembl;acc:q8nhw3]
Ranked
Squared
Rooted
2779 CAV3 Measured caveolin-3 (m-caveolin). [swissprot;acc:p56539]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/