Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Network Comparison Type Gene Rank Value Type description network_comparison red Interaction Map green Filtered
Results: HTML CSV LaTeX Showing element 1001 to 1050 of 1892 in total
Network Comparison Type  : Subtracted
network_comparison  : 0
red  : 0
Interaction Map  : High confidence
green  : 0
Filtered  : 1
Rank
Value Type
description
3006 Measured dgcr8 protein (digeorge syndrome critical region 8). [swissprot;acc:q8wyq5]
Ranked
Squared
Rooted
3007 Measured glioma-amplified sequence-41; numa binding protein 1. [refseq;acc:nm_006530]
Ranked
Squared
Rooted
3008 Measured nuclear pore complex protein nup214 (nucleoporin nup214) (214 kda nucleoporin) (can protein). [swissprot;acc:p35658]
Ranked
Squared
Rooted
3009 Measured cytochrome c oxidase polypeptide vib (ec 1.9.3.1) (aed). [swissprot;acc:p14854]
Ranked
Squared
Rooted
3010 Measured uroporphyrinogen decarboxylase (ec 4.1.1.37) (uro-d) (upd). [swissprot;acc:p06132]
Ranked
Squared
Rooted
3011 Measured dna replication licensing factor mcm8 (minichromosome maintenance 8). [swissprot;acc:q9uja3]
Ranked
Squared
Rooted
3012 Measured small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678]
Ranked
Squared
Rooted
3013 Measured major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]
Ranked
Squared
Rooted
3014 Measured mitochondrial deoxynucleotide carrier (mitochondrial uncoupling protein 1). [swissprot;acc:q9hc21]
Ranked
Squared
Rooted
3015 Measured pericentrin 1; frount; nucleoporin nup75. [refseq;acc:nm_024844]
Ranked
Squared
Rooted
3016 Measured mitochondrial ribosomal protein s7; 30s ribosomal protein s7 homolog. [refseq;acc:nm_015971]
Ranked
Squared
Rooted
3017 Measured leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]
Ranked
Squared
Rooted
3018 Measured cysteine-rich secretory protein-1 precursor (crisp-1) (acidic epididymal glycoprotein homolog) (aeg-like protein) (arp). [swissprot;acc:p54107]
Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/