Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Gene Value Type Network Comparison Type Interaction Map green Filtered red network_comparison
Results: HTML CSV LaTeX Showing element 501 to 550 of 8289 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1
description
Rank
Interaction Map
green
red
network_comparison
adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144] 4467 Low confidence 210.017 208.138 1.00903
adenylosuccinate lyase (ec 4.3.2.2) (adenylosuccinase) (asl) (asase). [swissprot;acc:p30566] 1608 195.607 199.691 1.02088
2067 High confidence 191.639 193.226 1.00828
adenylosuccinate synthase-like 1. [refseq;acc:nm_152328] 1192 Low confidence 194.529 199.02 1.02309
1661 High confidence 201.551 204.437 1.01432
adenylosuccinate synthetase (ec 6.3.4.4) (imp--aspartate ligase) (adss) (ampsase). [swissprot;acc:p30520] 1200 Low confidence 194.493 198.973 1.02303
1665 High confidence 201.564 204.433 1.01423
adenylyl cyclase-associated protein 1 (cap 1). [swissprot;acc:q01518] 1701 Low confidence 197.403 201.46 1.02055
1850 High confidence 213.587 215.931 1.01097
adenylyl cyclase-associated protein 2 (cap 2). [swissprot;acc:p40123] 1699 Low confidence 197.367 201.425 1.02056
1895 High confidence 213.639 215.853 1.01036
adhesion regulating molecule 1 precursor (110 kda cell membrane glycoprotein) (gp110). [swissprot;acc:q16186] 2369 219.434 218.555 1.00402
2525 Low confidence 199.602 203.221 1.01813
adipocyte plasma membrane-associated protein (bscv protein). [swissprot;acc:q9hdc9] 813 High confidence 221.785 212.386 1.04425
3843 Low confidence 198.793 201.394 1.01308
adiponectin receptor 2. [refseq;acc:nm_024551] 104 204.212 219.277 1.07377
185 High confidence 246.371 281.582 1.14292
adp,atp carrier protein, fibroblast isoform (adp/atp translocase 2) (adenine nucleotide translocator 2) (ant 2). [swissprot;acc:p05141] 1552 221.424 225.159 1.01687
1779 Low confidence 195.272 199.221 1.02022
adp,atp carrier protein, heart/skeletal muscle isoform t1 (adp/atp translocase 1) (adenine nucleotide translocator 1) (ant 1). [swissprot;acc:p12235] 1551 High confidence 221.424 225.159 1.01687
1772 Low confidence 195.276 199.226 1.02023
adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236] 1550 High confidence 221.424 225.159 1.01687
1780 Low confidence 195.256 199.201 1.0202
adp-ribose pyrophosphatase (ec 3.6.1.13) (adp-ribose diphosphatase) (adenosine diphosphoribose pyrophosphatase) (adpr-ppase) (adp-ribose phosphohydrolase) (nucleoside diphosphate-linked moiety x motif 9). [swissprot;acc:q9bw91] 2492 200.307 203.957 1.01822
adp-ribosylation factor 1. [swissprot;acc:p32889] 1229 198.315 202.83 1.02277
2128 High confidence 222.788 221.248 1.00696
adp-ribosylation factor 3. [swissprot;acc:p16587] 1164 Low confidence 198.252 202.869 1.02329
2130 High confidence 222.788 221.248 1.00696
adp-ribosylation factor 4. [swissprot;acc:p18085] 1165 Low confidence 198.216 202.831 1.02328
2123 High confidence 222.788 221.248 1.00696
adp-ribosylation factor 5. [swissprot;acc:p26437] 3558 Low confidence 196.554 199.425 1.01461
adp-ribosylation factor binding protein gga1 (golgi-localized, gamma ear-containing, arf-binding protein 1) (gamma-adaptin related protein 1). [swissprot;acc:q9ujy5] 3022 196.696 199.98 1.0167
adp-ribosylation factor binding protein gga2 (golgi-localized, gamma ear-containing, arf-binding protein 2) (gamma-adaptin related protein 2) (vear) (vhs domain and ear domain of gamma-adaptin). [swissprot;acc:q9ujy4] 3016 196.697 199.984 1.01671
adp-ribosylation factor binding protein gga3 (golgi-localized, gamma ear-containing, arf-binding protein 3). [swissprot;acc:q9nz52] 3030 196.693 199.971 1.01667
adp-ribosylation factor gtpase activating protein 1 (adp-ribosylation factor 1 gtpase activating protein) (arf1 gap) (arf1-directed gtpase- activating protein) (gap protein). [swissprot;acc:q8n6t3] 2156 High confidence 198.71 200.063 1.00681
2704 Low confidence 195.675 199.109 1.01755
adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61] 2137 High confidence 222.788 221.248 1.00696
3196 Low confidence 197.655 200.829 1.01606
adp-ribosylation factor guanine nucleotide factor 6; hepatocellular carcinoma-associated antigen 67. [refseq;acc:nm_015310] 4149 198.625 200.724 1.01057
adp-ribosylation factor-like protein 1. [swissprot;acc:p40616] 2613 High confidence 215.799 215.497 1.0014
4075 Low confidence 198.695 200.896 1.01108
adp-ribosylation factor-like protein 3. [swissprot;acc:p36405] 2520 High confidence 216.341 215.835 1.00234
4553 Low confidence 200.827 202.436 1.00801
adp-ribosylation factor-like protein 4. [swissprot;acc:p40617] 1188 High confidence 212.904 218.402 1.02582
2587 Low confidence 194.454 197.95 1.01798
adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559] 1186 High confidence 212.904 218.402 1.02582
2585 Low confidence 194.454 197.95 1.01798
adrenodoxin, mitochondrial precursor (adrenal ferredoxin) (hepatoredoxin) (ferredoxin 1). [swissprot;acc:p10109] 1074 187.103 191.57 1.02387
1105 High confidence 185.882 191.139 1.02828
adrenoleukodystrophy protein (aldp). [swissprot;acc:p33897] 1553 Low confidence 206.704 202.418 1.02117

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/