MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Network Comparison Type	Value Type	Filtered	Interaction Map	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 33156 in total

Network Comparison Type  : Divided
Filtered  : 1

Rank	description	Value Type	Interaction Map	network_comparison	red	green
1	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	Ranked	Low confidence	2	16	32
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Measured		4.4149	2399.5	543.5
		Squared		19.4914	1362.75	69.9153
		Rooted		2.10117	48.9847	23.3131
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Ranked	High confidence	2.4	10	24
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Measured		5.31521	450.5	2394.5
		Squared		28.2513	48.0356	1357.07
		Rooted		2.30547	21.225	48.9336
2	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Measured	Low confidence	4.4149	2399.5	543.5
		Squared		19.4914	1362.75	69.9153
		Rooted		2.10117	48.9847	23.3131
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Ranked		1.47982	223	330
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]		High confidence	1.86667	15	28
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Measured		5.31521	450.5	2394.5
		Squared		28.2513	48.0356	1357.07
		Rooted		2.30547	21.225	48.9336
3	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Ranked	Low confidence	1.47982	223	330
	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	Measured		4.4149	2399.5	543.5
		Squared		19.4914	1362.75	69.9153
		Rooted		2.10117	48.9847	23.3131
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Ranked	High confidence	1.86667	15	28
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Measured		3.71868	2597.5	698.5
		Squared		13.8285	1596.92	115.48
		Rooted		1.92839	50.9657	26.4292
4	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	Ranked	Low confidence	1.47982	223	330
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]		High confidence	1.86667	15	28
	hbs1-like. [refseq;acc:nm_006620]	Measured		3.71868	2597.5	698.5
		Squared		13.8285	1596.92	115.48
		Rooted		1.92839	50.9657	26.4292
	lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	Measured	Low confidence	4.4149	2399.5	543.5
		Squared		19.4914	1362.75	69.9153
		Rooted		2.10117	48.9847	23.3131
5	cytohesin 4. [swissprot;acc:q9uia0]	Ranked	High confidence	1.86667	15	28
	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	Measured		3.39764	1153.5	339.5
		Squared		11.544	314.926	27.2805
		Rooted		1.84327	33.9632	18.4255
	lysosome-associated membrane glycoprotein 2 precursor (lamp-2) (cd107b antigen). [swissprot;acc:p13473]	Ranked	Low confidence	1.47982	223	330
	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	Measured		2.86965	736.5	2113.5
		Squared		8.23493	128.386	1057.25
		Rooted		1.69401	27.1385	45.9728
6	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Ranked	High confidence	1.86667	15	28
	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Measured		3.39764	1153.5	339.5
		Squared		11.544	314.926	27.2805
		Rooted		1.84327	33.9632	18.4255
	oxysterol binding protein-related protein 3 (osbp-related protein 3) (orp-3). [swissprot;acc:q9h4l5]	Measured	Low confidence	2.86965	736.5	2113.5
		Squared		8.23493	128.386	1057.25
		Rooted		1.69401	27.1385	45.9728
	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]	Ranked		1.325	318	240
7	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]		High confidence	1.49767	215	322
	oxysterol binding protein-related protein 3 (osbp-related protein 3) (orp-3). [swissprot;acc:q9h4l5]		Low confidence	1.325	318	240

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.