Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Rank Gene description Value Type Network Comparison Type Interaction Map Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 812 to 861 of 3730 in total 
Value Type	Ranked
Network Comparison Type	Divided
Interaction Map	High confidence

Rank	description	Filtered	green	red	network_comparison	
406	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [source:swissprot;acc:q14186]	1	244.304	265.634	1.08731	
407	28s ribosomal protein s9, mitochondrial precursor (mrp-s9). [source:swissprot;acc:p82933]	1	260.544	239.75	1.08673	
407	udp-glucuronosyltransferase 2b10 precursor, microsomal (ec 2.4.1.17) (udpgt). [source:swissprot;acc:p36537]	0	10111.2	9783.63	1.03348	
408	ccaat-box-binding transcription factor (ccaat-binding factor) (cbf). [source:swissprot;acc:q03701]	1	234.804	255.112	1.08649	
408	udp-glucuronosyltransferase 2b15 precursor, microsomal (ec 2.4.1.17) (udpgt) (udpgth-3) (hlug4). [source:swissprot;acc:p54855]	0	10111.2	9783.63	1.03348	
409	rna polymerase i associated factor 53. [source:refseq;acc:nm_022490]	1	261.874	241.045	1.08641	
409	similar to cg7020 gene product (fragment). [source:sptrembl;acc:q96ib4]	0	10945.3	10598.5	1.03272	
410	histone h4. [source:swissprot;acc:p02304]	0	9308.99	9611.37	1.03248	
410	tfiih basal transcription factor complex p44 subunit (basic transcription factor 2 44 kda subunit) (btf2-p44) (general transcription factor iih polypeptide 2). [source:swissprot;acc:q13888]	1	253.539	233.376	1.0864	
411	60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [source:swissprot;acc:p35268]	0	12508.3	12115.7	1.0324	
411	tfiih basal transcription factor complex p62 subunit (basic transcription factor 62 kda subunit) (btf2-p62) (general transcription factor iih polypeptide 1). [source:swissprot;acc:p32780]	1	253.539	233.376	1.0864	
412	5-aminolevulinic acid synthase, nonspecific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-h). [source:swissprot;acc:p13196]	0	8279.69	8546.06	1.03217	
412	ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (ec 1.10.2.2) (rieske iron-sulfur protein) (risp). [source:swissprot;acc:p47985]	1	261.416	240.788	1.08567	
413	dna-directed rna polymerase i 40 kda polypeptide (ec 2.7.7.6) (rpa40) (rpa39). [source:swissprot;acc:o15160]	1	261.45	240.913	1.08525	
413	protein cgi-147. [source:swissprot;acc:q9y3e5]	0	5298.12	5135.25	1.03172	
414	germ cell-less. [source:refseq;acc:nm_022471]	0	10644.4	10978.8	1.03142	
414	katanin p60 subunit a 1. [source:refseq;acc:nm_007044]	1	252.238	232.431	1.08522	
415	katanin p80 subunit b 1; katanin (80 kda); katanin p80 (wd40-containing) subunit b 1. [source:refseq;acc:nm_005886]	1	252.166	232.382	1.08514	
415	transcription factor mafg (v-maf musculoaponeurotic fibrosarcoma oncogene homolog g) (hmaf). [source:swissprot;acc:o15525]	0	13166.3	13571.2	1.03075	
416	dna-directed rna polymerase i 135 kda polypeptide (ec 2.7.7.6) (rna polymerase i subunit 2) (rpa135). [source:swissprot;acc:q9h9y6]	1	261.041	240.6	1.08496	
416	transcription factor mafk (erythroid transcription factor nf-e2 p18 subunit). [source:swissprot;acc:o60675]	0	13202	13607.6	1.03072	
417	limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449]	0	10537.9	10854.8	1.03007	
417	set domain and mariner transposase fusion gene. [source:refseq;acc:nm_006515]	1	253.197	233.539	1.08417	
418	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [source:swissprot;acc:p18577]	0	17180.3	16680.7	1.02995	
418	cd209 antigen-like; putative type ii membrane protein. [source:refseq;acc:nm_014257]	1	253.197	233.539	1.08417	
419	blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [source:swissprot;acc:q02161]	0	17183	16684	1.02991	
419	low affinity immunoglobulin epsilon fc receptor (lymphocyte ige receptor) (fc-epsilon-rii) (cd23) (blast-2) (immunoglobulin e-binding factor). [source:swissprot;acc:p06734]	1	253.197	233.539	1.08417	
420	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [source:swissprot;acc:p18577]	0	17183	16684	1.02991	
420	cd209 antigen; dendritic cell-specific icam3-grabbing nonintegrin. [source:refseq;acc:nm_021155]	1	253.197	233.539	1.08417	
421	alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [source:swissprot;acc:p19652]	0	10866.3	11186	1.02942	
421	tuftelin-interacting protein 11 (hspc006). [source:swissprot;acc:q9ubb9]	1	205.9	223.202	1.08403	
422	glutamine synthetase (ec 6.3.1.2) (glutamate--ammonia ligase). [source:swissprot;acc:p15104]	0	12224.2	12581.7	1.02925	
422	ras-related protein rab-37. [source:swissprot;acc:q96ax2]	1	260.193	240.287	1.08284	
423	cylindromatosis (turban tumor syndrome); cylindromatosis 1, turban tumor syndrome. [source:refseq;acc:nm_015247]	0	6073	5905	1.02845	
423	ras-related protein rab-26. [source:swissprot;acc:q9ulw5]	1	260.193	240.287	1.08284	
424	dipeptidyl aminopeptidase-like protein 6 (dipeptidylpeptidase vi) (dipeptidylpeptidase 6) (dipeptidyl peptidase iv like protein) (dipeptidyl aminopeptidase-related protein) (dppx). [source:swissprot;acc:p42658]	0	9298.93	9562.48	1.02834	
424	dna-directed rna polymerase ii 33 kda polypeptide (ec 2.7.7.6) (rpb3) (rna polymerase ii subunit 3) (rpb33) (rpb31). [source:swissprot;acc:p19387]	1	260.193	240.287	1.08284	
425	max protein. [source:swissprot;acc:p25912]	1	210.561	227.828	1.082	
425	scribble. [source:refseq;acc:nm_015356]	0	12719	12370.5	1.02817	
426	atp-dependent dna helicase ii, 70 kda subunit (lupus ku autoantigen protein p70) (ku70) (70 kda subunit of ku antigen) (thyroid-lupus autoantigen) (tlaa) (ctc box binding factor 75 kda subunit) (ctcbf) (ctc75). [source:swissprot;acc:p12956]	0	9676.67	9412.67	1.02805	
426	dynactin 4. [source:refseq;acc:nm_032486]	1	252.253	233.142	1.08197	
427	apoptosis inhibitor fksg2. [source:swissprot;acc:q9hau6]	0	11582.7	11276.1	1.02719	
427	dna-directed rna polymerase ii 23 kda polypeptide (ec 2.7.7.6) (rpb25) (xap4) (rpb5) (rpabc1). [source:swissprot;acc:p19388]	1	259.525	239.977	1.08146	
428	atp-dependent rna helicase mgc2835; atp-dependent rna helicase; apoptosis related protein apr-5; dead box helicase 97 kda. [source:refseq;acc:nm_024072]	1	234.808	253.852	1.0811	
428	cleavage stimulation factor, 64 kda subunit (cstf 64 kda subunit) (cf-1 64 kda subunit). [source:swissprot;acc:p33240]	0	12301.2	11982.7	1.02658	
429	60s ribosomal protein l14 (cag-isl 7). [source:swissprot;acc:p50914]	0	12631.5	12318.7	1.02539	
429	polymerase (rna) iii (dna directed) (32kd). [source:refseq;acc:nm_006467]	1	259.038	239.709	1.08064	
430	splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [source:swissprot;acc:q15393]	0	11913.4	11621.7	1.0251	
430	u6 snrna-associated sm-like protein lsm5. [source:swissprot;acc:q9y4y9]	1	210.888	227.748	1.07995	
431	histone deacetylase 2 (hd2). [source:swissprot;acc:q92769]	0	9799.17	10043.7	1.02495	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/