MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Value Type	Rank	Gene	Network Comparison Type	Filtered	Interaction Map	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 29840 in total

Interaction Map  : High confidence

description	Value Type	Rank	Network Comparison Type	Filtered	red	green	network_comparison
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	Measured	37	Divided	0	334.401	934.348	2.79409
		45	Subtracted				599.947
		60	Divided	1	4489.19	2765.82	1.6231
		164	Subtracted				1723.37
	Ranked	18	Divided		185.678	245.247	1.32082
		54	Subtracted				59.569
		172		0	15260.6	13895.8	1364.8
		242	Divided				1.09822
	Squared	37			101.05	1034.13	10.2338
		131	Subtracted				933.08
		245	Divided	1	8875.01	6768.05	1.31131
		1962	Subtracted				2106.96
	Rooted	53	Divided	0	11.844	18.0183	1.5213
		64		1	63.8686	47.2654	1.35128
		67	Subtracted				16.6032
		69		0	11.844	18.0183	6.1743
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	Measured	310		1	7551.8	8630.06	1078.26
		509	Divided				1.14278
	Ranked	1038			186.741	181.041	1.03148
		1120	Subtracted				5.7
	Squared	274			30807.7	39351.7	8544
		295	Divided				1.27733
	Rooted	610	Subtracted		74.3557	79.1513	4.7956
		805	Divided				1.0645
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	Measured	307	Subtracted		7556.75	8636.87	1080.12
		508	Divided				1.14293
	Ranked	1032			186.664	180.943	1.03162
		1115	Subtracted				5.721
	Squared	273			30826.5	39383.9	8557.4
		294	Divided				1.2776
	Rooted	609	Subtracted		74.3877	79.1931	4.8054
		804	Divided				1.0646
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	Measured	319	Subtracted		7477	8532.02	1055.02
		514	Divided				1.1411
	Ranked	1048			187.96	182.308	1.031
		1128	Subtracted				5.652
	Squared	280			30566.4	38866.5	8300.1
		311	Divided				1.27154
	Rooted	631	Subtracted		73.8577	78.5795	4.7218
		822	Divided				1.06393
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	Measured	318	Subtracted		7485.08	8543.66	1058.58
		513	Divided				1.14143
	Ranked	1043			187.834	182.137	1.03128
		1121	Subtracted				5.697
	Squared	279			30596.2	38919.9	8323.7
		308	Divided				1.27205
	Rooted	616	Subtracted		73.9102	78.6514	4.7412
		811	Divided				1.06415
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	Measured	3126			0.00001	0.00001	1
			Subtracted		0	0	0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.