MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	Value Type	description	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 775 to 824 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	Value Type	description
2949	MFAP1	Squared	microfibrillar-associated protein 1. [swissprot;acc:p55081]
		Rooted
2950	TEGT	Measured	bax inhibitor-1 (bi-1) (testis enhanced gene transcript). [swissprot;acc:p55061]
		Ranked
		Squared
		Rooted
2951	ITGB7	Measured	integrin beta-7 precursor. [swissprot;acc:p26010]
		Ranked
		Squared
		Rooted
2952	ACVRL1	Measured	serine/threonine-protein kinase receptor r3 precursor (ec 2.7.1.37) (skr3) (activin receptor-like kinase 1) (alk-1) (tgf-b superfamily receptor type i) (tsr-i). [swissprot;acc:p37023]
		Ranked
		Squared
		Rooted
2953	GLIPR1	Measured	glioma pathogenesis-related protein (glipr) (rtvp-1 protein). [swissprot;acc:p48060]
		Ranked
		Squared
		Rooted
2954	NDUFA9	Measured	nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]
		Ranked
		Squared
		Rooted
2955	FBN2	Measured	fibrillin 2 precursor. [swissprot;acc:p35556]
		Ranked
		Squared
		Rooted
2956	SEC24B	Measured	protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487]
		Ranked
		Squared
		Rooted
2957	ENPEP	Measured	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]
		Ranked
		Squared
		Rooted
2958	CNOT6L	Measured	ccr4-not transcription complex, subunit 6-like. [refseq;acc:nm_144571]
		Ranked
		Squared
		Rooted
2959	no value	Measured	60s ribosomal protein l37a. [swissprot;acc:p12751]
		Ranked
		Squared
		Rooted
2960	AOX1	Measured	aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]
		Ranked
		Squared
		Rooted
2961	RAB1A	Measured	ras-related protein rab-1a (ypt1-related protein). [swissprot;acc:p11476]
		Ranked
		Squared
		Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.