MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Value Type	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1551 to 1600 of 3228 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

description	Rank	red	network_comparison	green
lin-7 homolog a; vertebrate lin7 homolog 1; tax interaction protein 33; mammalian lin-7 1. [refseq;acc:nm_004664]	1372	5743.45	1.07835	6193.45
lin-7 homolog b; lin-7b protein; likely ortholog of mouse lin-7b; mammalian lin-7 protein 2; likely orholog of mouse lin 7 homolog b (c. elegans). [refseq;acc:nm_022165]	1388	5743.39	1.07827	6192.94
lin-7 homolog c; lin-7 protein 3. [refseq;acc:nm_018362]	1395	5743.26	1.07813	6191.96
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (ec 2.3.1.-) (e2) (dihydrolipoamide branched chain transacylase) (bckad e2 subunit). [swissprot;acc:p11182]	1768	5829.61	1.06667	6218.27
lipoate-protein ligase, mitochondrial precursor (ec 6.-.-.-) (lipoate biosynthesis protein) (lipoyl ligase) (lipoyltransferase). [swissprot;acc:q9y234]	2389	6327.14	1.03987	6579.38
lipocalin-interacting membrane receptor. [refseq;acc:nm_018113]	1183	4392.63	1.08732	4776.19
lipoic acid synthetase, mitochondrial (lip-syn) (lipoate synthase) (hussy-01) (fragment). [swissprot;acc:o43766]	2508	6469.44	1.02548	6634.31
lipopolysaccharide-binding protein precursor (lbp). [swissprot;acc:p18428]	2334	5123.89	1.04428	5350.78
lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	2131	5328.73	1.05402	5616.59
liv-1 protein, estrogen regulated. [refseq;acc:nm_012319]	498	4682.87	1.1441	4093.05
loh1cr12. [refseq;acc:nm_058169]	842	5195.48	1.10512	5741.63
lon protease homolog, mitochondrial precursor (ec 3.4.21.-) (lon protease-like protein) (lonp) (lonhs). [swissprot;acc:p36776]	1598	5068.17	1.07147	5430.41
low affinity immunoglobulin epsilon fc receptor (lymphocyte ige receptor) (fc-epsilon-rii) (cd23) (blast-2) (immunoglobulin e-binding factor). [swissprot;acc:p06734]	2754	4521.42	1.0001	4521.87
luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	128	4355.61	1.3341	5810.82
luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	129	4358.13	1.33348	5811.49
lupus la protein (sjogren syndrome type b antigen) (ss-b) (la ribonucleoprotein) (la autoantigen). [swissprot;acc:p05455]	370	4108.15	1.17058	4808.93
lyl-1 protein (lymphoblastic leukemia derived sequence 1). [swissprot;acc:p12980]	3107	0.00001	1	0.00001
lymphoid enhancer binding factor 1 (lef-1) (t cell-specific transcription factor 1-alpha) (tcf1-alpha). [swissprot;acc:q9uju2]	891	5385.04	1.10188	5933.65
lysophospholipase i; lysophospholipase 1; lysophospholipid-specific lysophospholipase; acyl-protein thioesterase-1. [refseq;acc:nm_006330]	2017	6555.42	1.05849	6938.82
lysophospholipase ii; acyl-protein thioesterase. [refseq;acc:nm_007260]	2019
lysosomal acid lipase/cholesteryl ester hydrolase precursor (ec 3.1.1.13) (lal) (acid cholesteryl ester hydrolase) (sterol esterase) (lipase a) (cholesteryl esterase). [swissprot;acc:p38571]	1001	5680.76	1.095	6220.45
lysosomal alpha-mannosidase precursor (ec 3.2.1.24) (mannosidase, alpha b) (lysosomal acid alpha-mannosidase) (laman) (mannosidase alpha class 2b member 1). [swissprot;acc:o00754]	2677	7780.98	1.00515	7741.14
lysosomal trafficking regulator (beige homolog). [swissprot;acc:q99698]	2929	0.00001	1	0.00001
lysyl-trna synthetase (ec 6.1.1.6) (lysine--trna ligase) (lysrs). [swissprot;acc:q15046]	1808	4941.92	1.06539	5265.09
m-phase inducer phosphatase 1 (ec 3.1.3.48) (dual specificity phosphatase cdc25a). [swissprot;acc:p30304]	1896	4521	1.06285	4805.16
m-phase inducer phosphatase 2 (ec 3.1.3.48) (dual specificity phosphatase cdc25b). [swissprot;acc:p30305]	1989	4383.34	1.05922	4642.93
m-phase inducer phosphatase 3 (ec 3.1.3.48) (dual specificity phosphatase cdc25c). [swissprot;acc:p30307]	1940	4450.17	1.06094	4721.37
mab-21-like protein 1; mab-21-like 1. [refseq;acc:nm_005584]	2786	0.00001	1	0.00001
mab-21-like protein 2; mab-21-like 2. [refseq;acc:nm_006439]	2783
mad protein (max dimerizer). [swissprot;acc:q05195]	174	4455.95	1.2958	5774.03
mago nashi protein homolog. [swissprot;acc:p50606]	2864	0.00001	1	0.00001
maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168]	2101	5241.34	1.05493	5529.25
maguk p55 subfamily member 3 (mpp3 protein) (discs, large homolog 3). [swissprot;acc:q13368]	987	6660.04	1.09636	7301.81
maguk p55 subfamily member 6 (veli-associated maguk 1) (vam-1). [swissprot;acc:q9nzw5]	2091	5247.76	1.05526	5537.75
major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	3013	0.00001	1	0.00001
malate dehydrogenase, cytoplasmic (ec 1.1.1.37). [swissprot;acc:p40925]	3213
malate dehydrogenase, mitochondrial precursor (ec 1.1.1.37). [swissprot;acc:p40926]	2400	4368.44	1.03912	4539.34
maleylacetoacetate isomerase (ec 5.2.1.2) (maai) (glutathione s- transferase zeta 1) (ec 2.5.1.18) (gstz1-1). [swissprot;acc:o43708]	2486	3626.38	1.0299	3734.8
malonyl-coa decarboxylase, mitochondrial precursor (ec 4.1.1.9) (mcd). [swissprot;acc:o95822]	1604	6176.82	1.07141	6617.91
mam domain containing glycosylphosphatidylinositol anchor 1; glycosyl-phosphatidyl-inositol-mam. [refseq;acc:nm_153487]	3070	0.00001	1	0.00001
mannose-6-phosphate isomerase (ec 5.3.1.8) (phosphomannose isomerase) (pmi) (phosphohexomutase). [swissprot;acc:p34949]	1719	5458.12	1.06827	5830.76
mannose-p-dolichol utilization defect 1 protein (suppressor of lec15 and lec35 glycosylation mutation homolog) (sl15). [swissprot;acc:o75352]	884	5167.15	1.10224	5695.44
mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	220	41482.5	1.24361	33356.5
map kinase-activated protein kinase 2 (ec 2.7.1.-) (mapk-activated protein kinase 2) (mapkap kinase 2) (mapkapk-2). [swissprot;acc:p49137]	475	9649.61	1.14549	11053.5
map/microtubule affinity-regulating kinase 1. [refseq;acc:nm_018650]	2586	4180.32	1.0175	4253.46
map/microtubule affinity-regulating kinase 2 isoform b; elkl motif kinase 1; elkl motif kinase. [refseq;acc:nm_004954]	2587
maspin precursor (protease inhibitor 5). [swissprot;acc:p36952]	2405	5078.5	1.03884	5275.76
mast cell carboxypeptidase a precursor (ec 3.4.17.1) (mc-cpa) (carboxypeptidase a3). [swissprot;acc:p15088]	240	7711.36	1.23071	6265.79
mawd binding protein (unknown protein 32 from 2d-page of liver tissue). [swissprot;acc:p30039]	2018	6555.42	1.05849	6938.82
max dimerization protein 3; likely ortholog of mouse max dimerization protein 3. [refseq;acc:nm_031300]	177	4457.06	1.29539	5773.63

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.