MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Gene	Value Type	Rank	Interaction Map	network_comparison	description	red	green	Filtered

Results: HTML CSV LaTeX

Showing element 2663 to 2712 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

Rank	network_comparison	description	red	green
2663	1.00703	microtubule-actin crosslinking factor 1, isoform 4. [swissprot;acc:q96pk2]	4608.54	4576.35
2664	1.00702	bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8 (230 kda bullous pemphigoid antigen) (bpa) (hemidesmosomal plaque protein) (dystonia musculorum protein) (fragment). [swissprot;acc:q03001]	4608.91	4576.78
2665	1.007	anaphase promoting complex subunit 11 (hepatocellular carcinoma associated ring finger protein) (hspc214). [swissprot;acc:q9nyg5]	8936.97	8999.55
2666	1.00671	dyskerin (nucleolar protein nap57) (cbf5 homolog). [swissprot;acc:o60832]	4591.08	4621.88
2667	1.00666	dna-directed rna polymerase ii 7.6 kda polypeptide (ec 2.7.7.6) (rpb10) (rpb7.6) (rpabc5). [swissprot;acc:p52436]	4071.9	4099.01
2668	1.00652	iron-responsive element binding protein 1 (ire-bp 1) (iron regulatory protein 1) (irp1) (ferritin repressor protein) (aconitate hydratase) (ec 4.2.1.3) (citrate hydro-lyase) (aconitase). [swissprot;acc:p21399]	8222.61	8169.38
2669	1.0061	dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743]	4336.58	4310.3
2670	1.00609	dipeptidylpeptidase 9; dipeptidyl peptidase 9; dipeptidyl peptidase iv-related protein-2. [refseq;acc:nm_139159]	4336.62	4310.35
2671	1.00586	muscle-specific beta 1 integrin binding protein. [refseq;acc:nm_014446]	4338.79	4313.52
2672	1.00541	ubiquitin-specific protease otubain 2. [refseq;acc:nm_023112]	7350.69	7390.45
2673	1.00515	60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]	7780.98	7741.14
2674		sin3 associated polypeptide p30; sin3-associated polypeptide, 30kd. [refseq;acc:nm_003864]
2675		clathrin coat assembly protein ap50 (clathrin coat associated protein ap50) (plasma membrane adaptor ap-2 50 kda protein) (ha2 50 kda subunit) (clathrin assembly protein complex 2 medium chain) (ap-2 mu 2 chain). [swissprot;acc:p20172]
2676		atp-binding cassette, sub-family c, member 10; multidrug resistance-associated protein 7. [refseq;acc:nm_033450]
2677		lysosomal alpha-mannosidase precursor (ec 3.2.1.24) (mannosidase, alpha b) (lysosomal acid alpha-mannosidase) (laman) (mannosidase alpha class 2b member 1). [swissprot;acc:o00754]
2678		rna polymerase i transcription factor rrn3. [refseq;acc:nm_018427]
2679	1.00479	rho guanine nucleotide exchange factor 6 (pak-interacting exchange factor alpha) (alpha-pix) (cool-2). [swissprot;acc:q15052]	5358.78	5384.44
2680		serine/threonine-protein kinase pak 3 (ec 2.7.1.-) (p21-activated kinase 3) (pak-3) (beta-pak) (oligophrenin-3). [swissprot;acc:o75914]	5358.3	5383.94
2681	1.00478	serine/threonine-protein kinase pak 2 (ec 2.7.1.-) (p21-activated kinase 2) (pak-2) (pak65) (gamma-pak) (s6/h4 kinase). [swissprot;acc:q13177]	5358.31
2682		conserved oligomeric golgi complex subunit 5 (13s golgi transport complex 90 kda subunit) (gtc-90) (golgi transport complex 1). [swissprot;acc:q9up83]	5358.3	5383.93
2683		serine/threonine-protein kinase pak 1 (ec 2.7.1.-) (p21-activated kinase 1) (pak-1) (p65-pak) (alpha-pak). [swissprot;acc:q13153]
2684		rho guanine nucleotide exchange factor 7 (pak-interacting exchange factor beta) (beta-pix) (cool-1) (p85). [swissprot;acc:q14155]	5357.73	5383.33
2685	1.00475	cytochrome c1, heme protein, mitochondrial precursor (cytochrome c-1). [swissprot;acc:p08574]	3953.53	3972.32
2686		oligophrenin-1 like protein (gtpase regulator associated with focal adhesion kinase). [swissprot;acc:q9una1]
2687		senescence marker protein-30 (smp-30) (regucalcin) (rc). [swissprot;acc:q15493]
2688		oligophrenin 1. [swissprot;acc:o60890]
2689	1.00446	neuropilin- and tolloid-like protein 2 precursor. [refseq;acc:nm_018092]	4113.79	4095.53
2690		neuropilin- and tolloid-like protein 1 isoform 3 precursor. [refseq;acc:nm_138966]
2691		heterogenous nuclear ribonucleoprotein u (hnrnp u) (scaffold attachment factor a) (saf-a). [swissprot;acc:q00839]
2692		runt-related transcription factor 2 (core-binding factor, alpha 1 subunit) (cbf-alpha 1) (acute myeloid leukemia 3 protein) (oncogene aml-3) (polyomavirus enhancer binding protein 2 alpha a subunit) (pebp2-alpha a) (pea2-alpha a) (sl3-3 enhancer factor 1 alpha a subunit) (sl3/akv core-binding factor alpha a subunit) (osteoblast- specific transcription factor 2) (osf-2). [swissprot;acc:q13950]
2693		e1b-55kda-associated protein 5 isoform a. [refseq;acc:nm_007040]
2694		60s ribosomal protein l18. [swissprot;acc:q07020]
2695	1.00436	endonuclease g, mitochondrial precursor (ec 3.1.30.-) (endo g). [swissprot;acc:q14249]	5176.92	5154.43
2696		programmed cell death protein 8, mitochondrial precursor (ec 1.-.-.-) (apoptosis-inducing factor). [swissprot;acc:o95831]
2697		t-box transcription factor tbx6 (t-box protein 6). [swissprot;acc:o95947]
2698	1.0042	trub pseudouridine (psi) synthase homolog 1. [refseq;acc:nm_139169]	4163.36	4145.95
2699	1.00399	heterogeneous nuclear ribonucleoprotein m (hnrnp m). [swissprot;acc:p52272]	5356.83	5378.19
2700	1.00395	short coiled-coil protein; short coiled coil protein. [refseq;acc:nm_032547]	5239.33	5260
2701		dynein light chain 2. [refseq;acc:nm_080677]
2702	1.00393	creatine kinase, sarcomeric mitochondrial precursor (ec 2.7.3.2) (s- mtck) (mib-ck) (basic-type mitochondrial creatine kinase). [swissprot;acc:p17540]	8971.66	9006.92
2703	1.00388	creatine kinase, ubiquitous mitochondrial precursor (ec 2.7.3.2) (u- mtck) (mia-ck) (acidic-type mitochondrial creatine kinase). [swissprot;acc:p12532]	8972.87	9007.71
2704	1.0037	creatine kinase, m chain (ec 2.7.3.2) (m-ck). [swissprot;acc:p06732]	8980.12	9013.33
2705	1.00365	protein cgi-27 (c21orf19-like protein). [swissprot;acc:q9y316]	4137.61	4152.72
2706	1.00364	peptidyl prolyl isomerase h; cyclophilin h. [refseq;acc:nm_006347]	8979.61	9012.31
2707		prp18 pre-mrna processing factor 18 homolog. [refseq;acc:nm_003675]
2708	1.00363	j domain protein c21orf55. [swissprot;acc:q9nx36]	8979.78	9012.42
2709	1.00351	testis-specific protein tex28. [swissprot;acc:o15482]	5603.24	5583.64
2710		similar to nuclear protein e3-3 orf1. [sptrembl;acc:q9bu61]
2711		n-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase (ec 2.4.1.149) (poly-n-acetyllactosamine extension enzyme) (i-beta- 1,3-n-acetylglucosaminyltransferase) (ignt) (udp-glcnac:betagal beta- 1,3-n-acetylglucosaminyltransferase 6). [swissprot;acc:o43505]	5332.98	5351.72
2712		a kindred of iglon. [refseq;acc:nm_173808]	5603.24	5583.64

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.