Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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description green Value Type Rank Interaction Map Gene Network Comparison Type red Filtered network_comparison
Results: HTML CSV LaTeX Showing element 551 to 600 of 3228 in total
Value Type  : Ranked
Interaction Map  : High confidence
Network Comparison Type  : Divided
Filtered  : 1
description
green
Rank
red
network_comparison
cell division protein kinase 9 (ec 2.7.1.-) (serine/threonine-protein kinase pitalre) (c-2k). [swissprot;acc:p50750] 0.00001 2974 0.00001 1
cellular modulator of immune recognition. [refseq;acc:nm_145021] 212.672 1179 218.186 1.02593
cellular repressor of e1a-stimulated genes 2. [refseq;acc:nm_153836] 209.118 699 220.438 1.05413
cellular repressor of e1a-stimulated genes. [refseq;acc:nm_003851] 705
centaurin beta 1 (cnt-b1). [swissprot;acc:q15027] 220.812 2037 218.919 1.00865
centaurin beta 2 (cnt-b2). [swissprot;acc:q15057] 2035
centaurin beta 5 (cnt-b5). [swissprot;acc:q96p50] 2034
centaurin gamma 1. [swissprot;acc:q99490] 218.452 1924 220.659 1.0101
centaurin gamma 2. [swissprot;acc:q9upq3] 1922
centaurin gamma 3. [swissprot;acc:q96p47] 1925
centromere protein j; centrosomal p4.1-associated protein; lyst-interacting protein lip1; lag-3-associated protein. [refseq;acc:nm_018451] 202.105 1317 206.773 1.0231
centromere/kinetochore protein zw10 homolog. [swissprot;acc:o43264] 0.00001 3167 0.00001 1
cerebral cell adhesion molecule. [refseq;acc:nm_016174] 193.871 2508 194.349 1.00247
cg9578-like; yeast ypr037w and worm c02c2.6 predicted proteins-like. [refseq;acc:nm_152902] 205.556 172 174.667 1.17685
cgi-142; hepatoma-derived growth factor 2. [refseq;acc:nm_016073] 222.222 832 231.734 1.0428
cgthba protein (-14 gene protein). [swissprot;acc:q12980] 230.596 644 217.67 1.05938
channel associated protein of synapse-110 (chapsyn-110) (discs, large homolog 2). [swissprot;acc:q15700] 216.7 2657 216.934 1.00108
chaperone-activity of bc1 complex-like, mitochondrial precursor (chaperone-abc1-like). [swissprot;acc:q8ni60] 212.567 1730 215.336 1.01303
choline dehydrogenase. [refseq;acc:nm_018397] 214.149 1647 217.256 1.01451
choline o-acetyltransferase (ec 2.3.1.6) (choactase) (choline acetylase) (chat). [swissprot;acc:p28329] 213.702 1967 211.632 1.00978
cholinephosphate cytidylyltransferase a (ec 2.7.7.15) (phosphorylcholine transferase a) (ctp:phosphocholine cytidylyltransferase a) (ct a) (cct a) (cct-alpha). [swissprot;acc:p49585] 267.352 269 241.373 1.10763
cholinephosphate cytidylyltransferase b (ec 2.7.7.15) (phosphorylcholine transferase b) (ctp:phosphocholine cytidylyltransferase b) (ct b) (cct b) (cct-beta). [swissprot;acc:q9y5k3] 275
chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0] 256.835 234 287.41 1.11905
chromatin assembly factor 1 subunit c (caf-1 subunit c) (chromatin assembly factor i p48 subunit) (caf-i 48 kda subunit) (caf-ip48) (retinoblastoma binding protein p48) (retinoblastoma-binding protein 4) (rbbp-4) (msi1 protein homolog). [swissprot;acc:q09028] 228.297 282 252.39 1.10553
chromatin-specific transcription elongation factor large subunit. [refseq;acc:nm_007192] 228.762 902 237.62 1.03872
chromobox protein homolog 1 (heterochromatin protein 1 homolog beta) (hp1 beta) (modifier 1 protein) (m31) (heterochromatin protein p25). [swissprot;acc:p23197] 188.63 2535 188.228 1.00214
chromobox protein homolog 3 (heterochromatin protein 1 homolog gamma) (hp1 gamma) (modifier 2 protein) (hech). [swissprot;acc:q13185] 188.366 2509 187.902 1.00247
chromobox protein homolog 5 (heterochromatin protein 1 homolog alpha) (hp1 alpha) (antigen p25). [swissprot;acc:p45973] 188.326 2505 187.853 1.00252
chromodomain helicase dna binding protein 5. [refseq;acc:nm_015557] 284 335 312 1.09859
chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873] 330
chromodomain protein, y chromosome-like isoform a; cdy-like, autosomal; testis-specific chromodomain y-like protein. [refseq;acc:nm_004824] 193.467 2553 193.12 1.0018
chromodomain y-like protein 2. [refseq;acc:nm_152342] 193.46 2556 193.119 1.00177
chromosome 11 open reading frame2; chromosome 11 open reading frame2. [refseq;acc:nm_013265] 219.759 1211 214.364 1.02517
chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286] 298.263 153 249.663 1.19466
cirhin; testis expressed gene 292; cirrhosis, autosomal recessive 1a. [refseq;acc:nm_032830] 235.351 982 243.312 1.03383
cisplatin resistance related protein crr9p. [refseq;acc:nm_030782] 0.00001 3197 0.00001 1
clathrin coat assembly protein ap180 (clathrin coat associated protein ap180) (91 kda synaptosomal-associated protein). [swissprot;acc:o60641] 213.876 1392 218.471 1.02148
clathrin coat assembly protein ap50 (clathrin coat associated protein ap50) (plasma membrane adaptor ap-2 50 kda protein) (ha2 50 kda subunit) (clathrin assembly protein complex 2 medium chain) (ap-2 mu 2 chain). [swissprot;acc:p20172] 200.413 2208 199.129 1.00645
clathrin heavy chain 1 (clh-17). [swissprot;acc:q00610] 226.226 399 207.889 1.08821
clathrin heavy chain 2 (clh-22). [swissprot;acc:p53675] 226.209 405 207.931 1.0879
cleavage and polyadenylation specific factor 4, 30kd subunit; cleavage-polyadenylation specificity factor, 30kd; no arches-like (zebrafish) zinc finger protein; cleavage-polyadenylation specificity factor. [refseq;acc:nm_006693] 112.329 850 107.842 1.04161
cleavage and polyadenylation specific factor 5, 25 kd subunit; pre-mrna cleavage factor im (25kd); pre-mrna cleavage factor im, 25kd subunit. [refseq;acc:nm_007006] 216.195 1657 219.314 1.01443
cleavage and polyadenylation specific factor 6, 68 kd subunit; pre-mrna cleavage factor im (68kd); cleavage and polyadenylation specific factor 6, 68kd subunit; pre-mrna cleavage factor i, 68kd subunit. [refseq;acc:nm_007007] 214.55 1480 218.664 1.01918
cleavage and polyadenylation specificity factor, 100 kda subunit (cpsf 100 kda subunit) (fragment). [swissprot;acc:q9p2i0] 114.552 871 110.2 1.03949
cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570] 112.772 854 108.289 1.0414
cleavage and polyadenylation specificity factor, 73 kda subunit (cpsf 73 kda subunit). [swissprot;acc:q9ukf6] 120.375 1006 116.524 1.03305
cleavage stimulation factor subunit 3; cleavage stimulation factor, 3' pre-rna, subunit 3, 77kd. [refseq;acc:nm_001326] 125.004 1089 121.428 1.02945
cleavage stimulation factor, 50 kda subunit (cstf 50 kda subunit) (cf-1 50 kda subunit). [swissprot;acc:q05048] 0.00001 3129 0.00001 1
cleavage stimulation factor, 64 kda subunit (cstf 64 kda subunit) (cf-1 64 kda subunit). [swissprot;acc:p33240] 162.665 2140 161.547 1.00692
cleft lip and palate associated transmembrane protein 1. [refseq;acc:nm_001294] 235.583 756 224.434 1.04968

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/