Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered description Value Type Rank green Gene Interaction Map Network Comparison Type red network_comparison

Results: HTML CSV LaTeX

Showing element 1001 to 1050 of 14920 in total

Filtered	0
Interaction Map	High confidence
Network Comparison Type	Divided

description	Value Type	Rank	green	red	network_comparison	
keratin associated protein 9.2. [source:refseq;acc:nm_031961]	Measured	241	1079.01	1225.47	1.13574	
keratin associated protein 9.2. [source:refseq;acc:nm_031961]	Ranked	244	11579.9	10551.1	1.09751	
keratin associated protein 9.2. [source:refseq;acc:nm_031961]	Squared	332	3232.47	3693.52	1.14263	
keratin associated protein 9.2. [source:refseq;acc:nm_031961]	Rooted	194	20.9159	23.871	1.14128	
keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371]	Measured	246	1079.36	1225.09	1.13502	
keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371]	Ranked	249	11573.7	10551.6	1.09687	
keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371]	Squared	336	3222.6	3680.43	1.14207	
keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371]	Rooted	198	20.9331	23.8722	1.1404	
kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8]	Measured	349	898.833	957.833	1.06564	
kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8]	Ranked	482	6205.67	6156.33	1.00801	
kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8]	Squared	294	239.342	290.82	1.21508	
kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8]	Rooted	442	29.0619	29.7464	1.02355	
kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719]	Measured	373	2864.68	2713.5	1.05571	
kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719]	Ranked	232	11240.2	12394.7	1.10271	
kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719]	Squared	489	21619.8	21555.6	1.00298	
kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719]	Rooted	231	28.0435	25.0015	1.12167	
lamin b2. [source:swissprot;acc:q03252]	Measured	338	538.704	579.262	1.07529	
lamin b2. [source:swissprot;acc:q03252]	Ranked	171	13802	12135.4	1.13733	
lamin b2. [source:swissprot;acc:q03252]	Squared	385	494.357	539.519	1.09136	
lamin b2. [source:swissprot;acc:q03252]	Rooted	141	14.7595	17.4452	1.18196	
lats homolog 1. [source:refseq;acc:nm_004690]	Measured	112	112.25	160	1.42539	
lats homolog 1. [source:refseq;acc:nm_004690]	Ranked	454	14204.8	13933.5	1.01947	
lats homolog 1. [source:refseq;acc:nm_004690]	Squared	91	5.42219	12.5892	2.32179	
lats homolog 1. [source:refseq;acc:nm_004690]	Rooted	302	9.54479	10.2412	1.07296	
leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735]	Measured	462	11305	11170.7	1.01202	
leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735]	Ranked	31	5266.67	8082.33	1.53462	
leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735]	Squared	474	58207.8	58677.8	1.00807	
leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735]	Rooted	359	86.1594	82.3645	1.04607	
lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306]	Measured	413	634.192	613.385	1.03392	
lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306]	Ranked	283	11959.2	11107.1	1.07672	
lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306]	Squared	317	277.442	237.082	1.17024	
lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306]	Rooted	299	18.1126	19.4501	1.07384	
likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745]	Measured	288	1161.64	1293.73	1.11371	
likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745]	Ranked	489	8811.09	8854.04	1.00487	
likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745]	Squared	389	557.57	605.501	1.08596	
likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745]	Rooted	387	28.6255	29.6492	1.03576	
likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033]	Measured	145	372.961	287.903	1.29544	
likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033]	Ranked	138	10549.4	12384.7	1.17397	
likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033]	Squared	172	74.0536	47.4746	1.55986	
likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033]	Rooted	154	16.5305	14.1274	1.1701	
lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893]	Measured	33	39.8063	12.6208	3.15402	
lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893]	Ranked	218	17469.2	19355	1.10795	
lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893]	Squared	34	0.697197	0.0435834	15.9968	
lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893]	Rooted	88	4.6274	3.4819	1.32899	
limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449]	Measured	440	7000.85	6830.67	1.02491	
limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449]	Ranked	417	10537.9	10854.8	1.03007	
limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449]	Squared	487	68294.1	68035.1	1.00381	
limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449]	Rooted	482	45.9175	46.0965	1.0039	
lipocalin-interacting membrane receptor. [source:refseq;acc:nm_018113]	Measured	159	574.372	734.025	1.27796	
lipocalin-interacting membrane receptor. [source:refseq;acc:nm_018113]	Ranked	474	11167.6	11290.1	1.01097	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/