Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Filtered description Value Type Rank green Gene Interaction Map Network Comparison Type red network_comparison
Results: HTML CSV LaTeX Showing element 1001 to 1050 of 14920 in total
Filtered	0
Interaction Map High confidence
Network Comparison Type Divided
description Value Type Rank green red network_comparison keratin associated protein 9.2. [source:refseq;acc:nm_031961] Measured 241 1079.01 1225.47 1.13574 keratin associated protein 9.2. [source:refseq;acc:nm_031961] Ranked 244 11579.9 10551.1 1.09751 keratin associated protein 9.2. [source:refseq;acc:nm_031961] Squared 332 3232.47 3693.52 1.14263 keratin associated protein 9.2. [source:refseq;acc:nm_031961] Rooted 194 20.9159 23.871 1.14128 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371] Measured 246 1079.36 1225.09 1.13502 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371] Ranked 249 11573.7 10551.6 1.09687 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371] Squared 336 3222.6 3680.43 1.14207 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371] Rooted 198 20.9331 23.8722 1.1404 kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8] Measured 349 898.833 957.833 1.06564 kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8] Ranked 482 6205.67 6156.33 1.00801 kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8] Squared 294 239.342 290.82 1.21508 kinesin-like protein kif13b (kinesin-like protein gakin). [source:swissprot;acc:q9nqt8] Rooted 442 29.0619 29.7464 1.02355 kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719] Measured 373 2864.68 2713.5 1.05571 kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719] Ranked 232 11240.2 12394.7 1.10271 kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719] Squared 489 21619.8 21555.6 1.00298 kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [source:swissprot;acc:q16719] Rooted 231 28.0435 25.0015 1.12167 lamin b2. [source:swissprot;acc:q03252] Measured 338 538.704 579.262 1.07529 lamin b2. [source:swissprot;acc:q03252] Ranked 171 13802 12135.4 1.13733 lamin b2. [source:swissprot;acc:q03252] Squared 385 494.357 539.519 1.09136 lamin b2. [source:swissprot;acc:q03252] Rooted 141 14.7595 17.4452 1.18196 lats homolog 1. [source:refseq;acc:nm_004690] Measured 112 112.25 160 1.42539 lats homolog 1. [source:refseq;acc:nm_004690] Ranked 454 14204.8 13933.5 1.01947 lats homolog 1. [source:refseq;acc:nm_004690] Squared 91 5.42219 12.5892 2.32179 lats homolog 1. [source:refseq;acc:nm_004690] Rooted 302 9.54479 10.2412 1.07296 leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735] Measured 462 11305 11170.7 1.01202 leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735] Ranked 31 5266.67 8082.33 1.53462 leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735] Squared 474 58207.8 58677.8 1.00807 leucine rich repeat (in flii) interacting protein 1. [source:refseq;acc:nm_004735] Rooted 359 86.1594 82.3645 1.04607 lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306] Measured 413 634.192 613.385 1.03392 lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306] Ranked 283 11959.2 11107.1 1.07672 lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306] Squared 317 277.442 237.082 1.17024 lifeguard; kiaa0950 protein. [source:refseq;acc:nm_012306] Rooted 299 18.1126 19.4501 1.07384 likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745] Measured 288 1161.64 1293.73 1.11371 likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745] Ranked 489 8811.09 8854.04 1.00487 likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745] Squared 389 557.57 605.501 1.08596 likely ortholog of mouse shc sh2-domain binding protein 1. [source:refseq;acc:nm_024745] Rooted 387 28.6255 29.6492 1.03576 likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033] Measured 145 372.961 287.903 1.29544 likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033] Ranked 138 10549.4 12384.7 1.17397 likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033] Squared 172 74.0536 47.4746 1.55986 likely ortholog of rat cytochrome p450 4x1. [source:refseq;acc:nm_178033] Rooted 154 16.5305 14.1274 1.1701 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893] Measured 33 39.8063 12.6208 3.15402 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893] Ranked 218 17469.2 19355 1.10795 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893] Squared 34 0.697197 0.0435834 15.9968 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [source:refseq;acc:nm_003893] Rooted 88 4.6274 3.4819 1.32899 limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449] Measured 440 7000.85 6830.67 1.02491 limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449] Ranked 417 10537.9 10854.8 1.03007 limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449] Squared 487 68294.1 68035.1 1.00381 limbic system-associated membrane protein precursor (lsamp). [source:swissprot;acc:q13449] Rooted 482 45.9175 46.0965 1.0039 lipocalin-interacting membrane receptor. [source:refseq;acc:nm_018113] Measured 159 574.372 734.025 1.27796 lipocalin-interacting membrane receptor. [source:refseq;acc:nm_018113] Ranked 474 11167.6 11290.1 1.01097 Legend: - Rank is the rank after comparing the two networks - Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions. - Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them - Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions. - Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/