Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Rank Gene description Value Type Filtered Network Comparison Type Interaction Map red network_comparison green

Results: HTML CSV LaTeX

Showing element 501 to 550 of 33156 in total

Filtered	1
Network Comparison Type	Divided

Rank	description	Value Type	Interaction Map	red	network_comparison	green	
63	melanoma-associated antigen f1 (mage-f1 antigen). [source:swissprot;acc:q9hay2]	Squared	High confidence	219048	1.68808	129762	
63	myosin xv (unconventional myosin-15). [source:swissprot;acc:q9ukn7]	Measured	High confidence	4489.19	1.6231	2765.82	
63	putative rna-binding protein 7 (rna binding motif protein 7). [source:swissprot;acc:q9y580]	Ranked	Low confidence	265.688	1.10749	239.902	
63	t-box transcription factor tbx19 (t-box protein 19). [source:swissprot;acc:o60806]	Rooted	Low confidence	61.4851	1.10801	68.1264	
64	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [source:swissprot;acc:q04446]	Rooted	High confidence	63.8686	1.35128	47.2654	
64	glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [source:swissprot;acc:p11217]	Measured	High confidence	4489.19	1.6231	2765.82	
64	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [source:swissprot;acc:p50152]	Ranked	High confidence	266.868	1.25965	336.159	
64	melanoma antigen, family b, 6. [source:refseq;acc:nm_173523]	Squared	High confidence	219048	1.68808	129762	
64	neurochondrin. [source:refseq;acc:nm_014284]	Squared	Low confidence	73677.6	1.28138	57498.7	
64	rab11-family interacting protein 4. [source:refseq;acc:nm_032932]	Rooted	Low confidence	73.6221	1.10693	81.4944	
64	retinal short-chain dehydrogenase/reductase 3. [source:refseq;acc:nm_016246]	Measured	Low confidence	15464.1	1.13635	17572.7	
64	transcription factor jun-d. [source:swissprot;acc:p17535]	Ranked	Low confidence	202.709	1.10552	183.361	
65	eferin. [source:swissprot;acc:o75154]	Rooted	Low confidence	73.6221	1.10693	81.4944	
65	glycogen phosphorylase, brain form (ec 2.4.1.1). [source:swissprot;acc:p11216]	Rooted	High confidence	63.8686	1.35128	47.2654	
65	guanine nucleotide-binding protein g(q), alpha subunit. [source:swissprot;acc:p50148]	Ranked	High confidence	267.136	1.25807	336.077	
65	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [source:swissprot;acc:p43358]	Squared	High confidence	219048	1.68808	129762	
65	neuralized-like. [source:refseq;acc:nm_004210]	Measured	High confidence	1657.68	1.6229	2690.25	
65	septin 6. [source:swissprot;acc:q14141]	Measured	Low confidence	13005.8	1.13593	14773.7	
65	septin-like protein kiaa0202 (fragment). [source:swissprot;acc:q92599]	Squared	Low confidence	75490.8	1.26497	95493.3	
65	transcription factor jun-b. [source:swissprot;acc:p17275]	Ranked	Low confidence	202.728	1.10546	183.388	
66	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Rooted	Low confidence	55.8923	1.10573	61.8016	
66	glycogen phosphorylase, liver form (ec 2.4.1.1). [source:swissprot;acc:p06737]	Rooted	High confidence	63.8686	1.35128	47.2654	
66	guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [source:swissprot;acc:p29992]	Ranked	High confidence	267.136	1.25807	336.077	
66	melanoma-associated antigen 9 (mage-9 antigen). [source:swissprot;acc:p43362]	Squared	High confidence	219048	1.68808	129762	
66	mitochondrial tumor suppressor gene 1; transcription factor mtsg1; at2 receptor-interacting protein 1; erythroid differentiation-related gene. [source:refseq;acc:nm_020749]	Ranked	Low confidence	221.902	1.10518	200.783	
66	nadh-ubiquinone oxidoreductase subunit b17.2 (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b17.2) (ci-b17.2) (cib17.2) (13 kda differentiation-associated protein). [source:swissprot;acc:q9ui09]	Measured	High confidence	1991.03	1.61795	3221.38	
66	septin 10 isoform 1. [source:refseq;acc:nm_144710]	Squared	Low confidence	74803.9	1.26038	94281	
66	son protein (son3) (negative regulatory element-binding protein) (nre- binding protein) (dbp-5) (bax antagonist selected in saccharomyces 1) (bass1) (protein c21orf50). [source:swissprot;acc:p18583]	Measured	Low confidence	4900.7	1.13368	5555.81	
67	beta-arrestin 2 (arrestin, beta 2). [source:swissprot;acc:p32121]	Measured	High confidence	6475.5	1.59177	10307.5	
67	brachyury protein (t protein). [source:swissprot;acc:o15178]	Rooted	Low confidence	61.687	1.10559	68.2003	
67	guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [source:swissprot;acc:p19087]	Ranked	High confidence	267.14	1.25805	336.075	
67	hira-interacting protein 5 (cgi-33). [source:swissprot;acc:q9ums0]	Measured	Low confidence	12176.9	1.1318	13781.8	
67	melanoma-associated antigen 8 (mage-8 antigen). [source:swissprot;acc:p43361]	Squared	High confidence	219048	1.68808	129762	
67	myosin xv (unconventional myosin-15). [source:swissprot;acc:q9ukn7]	Rooted	High confidence	63.8686	1.35128	47.2654	
67	retinoblastoma-associated factor 600. [source:refseq;acc:nm_020765]	Ranked	Low confidence	165.535	1.10505	149.799	
67	septin 6. [source:swissprot;acc:q14141]	Squared	Low confidence	74378.4	1.25751	93531.9	
68	60s ribosomal protein l37a. [source:swissprot;acc:p12751]	Ranked	Low confidence	239.692	1.10455	217.005	
68	beta-arrestin 1 (arrestin, beta 1). [source:swissprot;acc:p49407]	Measured	High confidence	6475.5	1.59177	10307.5	
68	glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [source:swissprot;acc:p11217]	Rooted	High confidence	63.8686	1.35128	47.2654	
68	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [source:swissprot;acc:p19086]	Ranked	High confidence	267.139	1.25805	336.075	
68	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [source:swissprot;acc:o60732]	Squared	High confidence	219048	1.68808	129762	
68	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [source:refseq;acc:nm_016172]	Measured	Low confidence	19498.1	1.12932	17265.4	
68	ras gtpase-activating protein ngap (ras protein activator like 1). [source:swissprot;acc:q9ujf2]	Rooted	Low confidence	55.9786	1.10514	61.8641	
68	retinoblastoma-associated factor 600. [source:refseq;acc:nm_020765]	Squared	Low confidence	27909.1	1.25653	35068.7	
69	amino acid transporter xat2; likely ortholog of mouse aspartate/glutamate transporter 1 (agt1). [source:refseq;acc:nm_138817]	Measured	Low confidence	6991.78	1.12253	7848.45	
69	amyloid beta a4 precursor protein-binding family a member 1 (neuron- specific x11 protein) (neuronal munc18-1-interacting protein 1) (mint-1) (adapter protein x11alpha). [source:swissprot;acc:q02410]	Rooted	Low confidence	60.7884	1.10405	67.1136	
69	delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (ec 1.5.1.12) (p5c dehydrogenase). [source:swissprot;acc:p30038]	Squared	Low confidence	80538.1	1.25465	64191.7	
69	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [source:swissprot;acc:p11488]	Ranked	High confidence	267.14	1.25805	336.075	
69	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [source:swissprot;acc:p43365]	Squared	High confidence	219048	1.68808	129762	
69	neurogenic differentiation factor 2 (neurod2). [source:swissprot;acc:q15784]	Rooted	High confidence	27.9136	1.33581	37.2872	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/