MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	Rank	Gene	description	Network Comparison Type	network_comparison	Interaction Map	red

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	Rank	description	Network Comparison Type	network_comparison	Interaction Map	red
322.947	148	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]	Divided	1.26947	Low confidence	409.972
	469		Subtracted	87.025
323.433	150	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]	Divided	1.26852		410.28
	470		Subtracted	86.847
323.685	151	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	Divided	1.26808		410.457
	471		Subtracted	86.772
327.517	55	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	Divided	1.92644	High confidence	630.942
	103		Subtracted	303.425
330.189	54	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	Divided	1.93484		638.862
	101		Subtracted	308.673
335	133	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]	Divided	1.32937		252
	314		Subtracted	83
336.584	143	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Divided	1.28908	Low confidence	261.105
	157				High confidence
	319		Subtracted	75.479
	497				Low confidence
339.154	207	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]	Divided	1.19069	High confidence	403.827
	331		Subtracted	64.673
339.779	485	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	Divided	1.06422	Low confidence	361.601
	733		Subtracted	21.822
346.751	134	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]	Divided	1.32862	High confidence	260.986
	309		Subtracted	85.765
351.772	68	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]	Divided	1.76802		198.964
	209		Subtracted	152.808
352.75	71	ubiquitin protein ligase. [refseq;acc:nm_130466]	Divided	1.75762		620
	119		Subtracted	267.25
354.349	318	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]	Divided	1.16138	Low confidence	305.111
	599		Subtracted	49.238
359.631	120	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]	Divided	1.37479	High confidence	494.417
	238		Subtracted	134.786
359.98	382	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	Divided	1.04852		377.445
	433		Subtracted	17.465
362.023	383	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	Divided	1.04825		379.489
	432		Subtracted	17.466
362.955	101	60s ribosomal protein l37a. [swissprot;acc:p12751]	Divided	1.47569	Low confidence	535.61
	301		Subtracted	172.655
363	203	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	Divided	1.19408	High confidence	304
	296				Low confidence
	343		Subtracted	59	High confidence
	555				Low confidence
368.317	229	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	Divided	1.14829	High confidence	320.752
	370		Subtracted	47.565
369.011	227	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	Divided	1.14972		424.258
	349		Subtracted	55.247
372.961	145	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]	Divided	1.29544		287.903
	312		Subtracted	85.058
375.343	179	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]	Divided	1.21433	Low confidence	455.789
	481		Subtracted	80.446
377.574	146	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]	Divided	1.29466	High confidence	291.639
	308		Subtracted	85.935

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.