MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

green	Filtered	description	Gene	red	Rank	Interaction Map	Value Type	network_comparison	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 401 to 450 of 77072 in total

green  : 0
Filtered  : 1
red  : 0
network_comparison  : 0
Network Comparison Type  : Subtracted

description	Rank	Interaction Map	Value Type
cop-coated vesicle membrane protein p24 precursor (p24a). [swissprot;acc:q15363]	3168	High confidence	Squared
			Rooted
cop9 signalosome complex subunit 1 (g protein pathway suppressor 1) (gps1 protein) (mfh protein). [swissprot;acc:q13098]	2827		Measured
			Ranked
			Squared
			Rooted
cop9 signalosome complex subunit 2 (signalosome subunit 2) (sgn2) (thyroid receptor interacting protein 15) (trip15). [swissprot;acc:q15647]	2841		Measured
			Ranked
			Squared
			Rooted
core-binding factor, beta subunit (cbf-beta) (polyomavirus enhancer binding protein 2 beta subunit) (pebp2-beta) (pea2-beta) (sl3-3 enhancer factor 1 beta subunit) (sl3/akv core-binding factor beta subunit). [swissprot;acc:q13951]	3183		Measured
			Ranked
			Squared
			Rooted
	5059	Low confidence	Measured
			Ranked
			Squared
			Rooted
ctcl tumor antigen l14-2. [refseq;acc:nm_018017]	2846	High confidence	Measured
			Ranked
			Squared
			Rooted
cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	2983		Measured
			Ranked
			Squared
			Rooted
cyclin k. [swissprot;acc:o75909]	3160		Measured
			Ranked
			Squared
			Rooted
cyclin t1 (cyclin t) (cyct1). [swissprot;acc:o60563]	3002		Measured
			Ranked
			Squared
			Rooted
cyclin t2. [swissprot;acc:o60583]	3171		Measured
			Ranked
			Squared
			Rooted
cyclin-dependent kinase (cdc2-like) 11; death-preventing kinase. [refseq;acc:nm_015076]	2892		Measured
			Ranked
			Squared
			Rooted
cyr61 protein precursor (cysteine-rich, angiogenic inducer, 61) (insulin-like growth factor-binding protein 10) (gig1 protein). [swissprot;acc:o00622]	2938		Measured
			Ranked
			Squared
			Rooted
cysteine-rich secretory protein-1 precursor (crisp-1) (acidic epididymal glycoprotein homolog) (aeg-like protein) (arp). [swissprot;acc:p54107]	3018		Measured
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.