Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank description Value Type Network Comparison Type green Interaction Map Filtered red network_comparison
Results: HTML CSV LaTeX Showing element 401 to 450 of 7460 in total
Value Type  : Measured
Interaction Map  : High confidence
Rank
description
Network Comparison Type
green
Filtered
red
network_comparison
101 cullin homolog 2 (cul-2). [swissprot;acc:q13617] Divided 3225.65 1 2353.63 1.3705
formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892] Subtracted 330.189 0 638.862 308.673
putative phosphoglycerate mutase 3 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13). [swissprot;acc:q8n0y7] Divided 977 1442 1.47595
septin 4 (peanut-like protein 2) (brain protein h5) (cell division control-related protein 2) (hcdcrel-2) (bradeion beta) (ce5b3 beta) (cerebral protein-7) (hucep-7). [swissprot;acc:o43236] Subtracted 17655.2 1 14924.4 2730.8
102 associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799] 8508.5 11068 2559.5
p28 ing5. [refseq;acc:nm_032329] 2243.69 0 2551.23 307.54
phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669] Divided 977 1442 1.47595
presenilin 1 (ps-1) (s182 protein). [swissprot;acc:p49768] 3225.65 1 2353.63 1.3705
103 cullin homolog 1 (cul-1). [swissprot;acc:q13616]
huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404] Subtracted 327.517 0 630.942 303.425
putative breast adenocarcinoma marker (32kd). [refseq;acc:nm_014453] 8508.5 1 11068 2559.5
transketolase-like 1 (ec 2.2.1.1) (transketolase 2) (tk 2) (transketolase related protein). [swissprot;acc:p51854] Divided 290.667 0 197.333 1.47298
104 associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463] Subtracted 8508.5 1 11068 2559.5
musashi 2 isoform a. [refseq;acc:nm_138962] Divided 5810.79 4241.57 1.36996
nucleoporin nup43 (p42). [swissprot;acc:q8nfh3] 7500.75 0 5106.93 1.46874
soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825] Subtracted 385.626 688.436 302.81
105 coatomer beta' subunit (beta'-coat protein) (beta'-cop) (p102). [swissprot;acc:p35606] 5130.58 5427.25 296.67
fos-related antigen 2. [swissprot;acc:p15408] Divided 2208.1 3233.86 1.46454
musashi 1. [refseq;acc:nm_002442] 5810.79 1 4241.57 1.36996
neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079] Subtracted 8508.5 11068 2559.5
106 inosine-5'-monophosphate dehydrogenase 2 (ec 1.1.1.205) (imp dehydrogenase 2) (impdh-ii) (impd 2). [swissprot;acc:p12268] 416.524 0 712.071 295.547
nuclear protein ukp68. [refseq;acc:nm_024824] Divided 5810.79 1 4241.57 1.36996
protein hspc134 (protein cda04). [swissprot;acc:q9by43] Subtracted 8508.5 11068 2559.5
tfiih basal transcription factor complex p44 subunit (basic transcription factor 2 44 kda subunit) (btf2-p44) (general transcription factor iih polypeptide 2). [swissprot;acc:q13888] Divided 858.525 0 1251.66 1.45792
107 20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298] 5843.51 1 4266.04 1.36977
60s ribosomal protein l7. [swissprot;acc:p18124] Subtracted 2206.07 0 1915.27 290.8
isoleucyl-trna synthetase, cytoplasmic (ec 6.1.1.5) (isoleucine--trna ligase) (ilers) (irs). [swissprot;acc:p41252] Divided 472.605 326.677 1.4467
septin 1 (larp) (serologically defined breast cancer antigen ny-br- 24). [swissprot;acc:q8wyj6] Subtracted 16780.7 1 14229.2 2551.5
108 basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811] Divided 421 0 292 1.44178
filamin b, beta (actin binding protein 278); beta filamin; filamin 1 (actin-binding protein-280)-like; filamin b, beta (actin-binding protein-278); filamin b, beta. [refseq;acc:nm_001457] 5899.76 1 4366.44 1.35116
microtubule-associated protein, rp/eb family, member 2; t-cell activation protein, eb1 family; apc-binding protein eb1. [refseq;acc:nm_014268] Subtracted 192.295 0 482.426 290.131
ral guanine nucleotide dissociation stimulator (ralgef) (ralgds). [swissprot;acc:q12967] 11523 1 14021.4 2498.4
109 44050 protein. [refseq;acc:nm_178832] 14889.2 17385.9 2496.7
dead-box protein abstrakt homolog. [swissprot;acc:q9ujv9] Divided 144 0 100 1.44
rev1-like; rev1 protein; rev1 (yeast homolog)- like. [refseq;acc:nm_016316] 5899.76 1 4366.44 1.35116
vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670] Subtracted 1222.89 0 934.726 288.164
110 dj681n20.2 (novel protein similar to ferritin, light polypeptide (ftl)). [sptrembl;acc:q9byw6] 816.5 528.5 288
nuclear inhibitor of protein phosphatase-1 (nipp-1) (protein phosphatase 1, regulatory inhibitor subunit 8) [includes: activator of rna decay (ec 3.1.4.-) (ard-1)]. [swissprot;acc:q12972] 14889.2 1 17385.9 2496.7
protein arginine n-methyltransferase 1 (ec 2.1.1.-) (interferon receptor 1-bound protein 4). [swissprot;acc:q99873] Divided 5899.76 4366.44 1.35116
spectrin alpha chain, brain (spectrin, non-erythroid alpha chain) (alpha-ii spectrin) (fodrin alpha chain). [swissprot;acc:q13813] 2637 0 1833 1.43863
111 protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22] 5899.76 1 4366.44 1.35116
ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464] 2063 0 2965.5 1.43747
succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (ec 1.3.5.1) (fp) (flavoprotein subunit of complex ii). [swissprot;acc:p31040] Subtracted 10535 10247.8 287.2
t-complex protein 1, gamma subunit (tcp-1-gamma) (cct-gamma). [swissprot;acc:p49368] 14824.9 1 12365.2 2459.7
112 autophagy protein 12-like (apg12-like). [swissprot;acc:o94817] 9352.11 11757.8 2405.69
lats homolog 1. [refseq;acc:nm_004690] Divided 112.25 0 160 1.42539
probable calcium-transporting atpase kiaa0703 (ec 3.6.3.8). [swissprot;acc:o75185] Subtracted 812.166 1095.42 283.254
u1 small nuclear ribonucleoprotein 70 kda (u1 snrnp 70 kda) (snrnp70) (u1-70k). [swissprot;acc:p08621] Divided 5899.76 1 4366.44 1.35116
113 cyclic-amp-dependent transcription factor atf-3 (activating transcription factor 3). [swissprot;acc:p18847] Subtracted 7132.71 4800.81 2331.9
filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333] Divided 5899.76 4366.44 1.35116

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/