MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	Value Type	description	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 62 to 111 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	Value Type	description
2771	TBX1	Ranked	t-box transcription factor tbx1 (t-box protein 1) (testis-specific t-box protein). [swissprot;acc:o43435]
		Squared
		Rooted
2772	NUDT14	Measured	uridine diphosphate glucose pyrophosphatase. [refseq;acc:nm_177533]
		Ranked
		Squared
		Rooted
2773	BMP8A	Measured	bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820]
		Ranked
		Squared
		Rooted
2774	C3orf37	Measured	dc12 protein. [refseq;acc:nm_020187]
		Ranked
		Squared
		Rooted
2775	JRKL	Measured	jerky protein homolog like (hhmjg). [swissprot;acc:q9y4a0]
		Ranked
		Squared
		Rooted
2776	BCOR	Measured	bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]
		Ranked
		Squared
		Rooted
2777	RABIF	Measured	guanine nucleotide exchange factor mss4 (rab interacting factor). [swissprot;acc:p47224]
		Ranked
		Squared
		Rooted
2778	MAFA	Measured	transcription factor mammalian mafa (pancreatic beta-cell specific transcriptional activator). [sptrembl;acc:q8nhw3]
		Ranked
		Squared
		Rooted
2779	CAV3	Measured	caveolin-3 (m-caveolin). [swissprot;acc:p56539]
		Ranked
		Squared
		Rooted
2780	KPNA2	Measured	importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292]
		Ranked
		Squared
		Rooted
2781	EXOC7	Measured	exocyst complex component exo70. [swissprot;acc:q9upt5]
		Ranked
		Squared
		Rooted
2782	ATP6AP2	Measured	vacuolar atp synthase membrane sector associated protein m8-9 (v-atpase m8.9 subunit). [swissprot;acc:o75787]
		Ranked
		Squared
		Rooted
2783	MAB21L2	Measured	mab-21-like protein 2; mab-21-like 2. [refseq;acc:nm_006439]
		Ranked
		Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.