Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Rank Gene Value Type description Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 608 to 657 of 12912 in total
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
Rank
Value Type
description
red
green
network_comparison
152 Rooted luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019] 55.2859 65.9288 1.19251
153 Measured hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703] 23693.7 18263 1.29736
Ranked chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286] 249.663 298.263 1.19466
Squared ret finger protein 2 (leukemia associated protein 5) (b-cell chronic lymphocytic leukemia tumor suppressor leu5) (putative tumor suppressor rfp2) (tripartite motif protein 13). [swissprot;acc:o60858] 70011 49783 1.40632
Rooted luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032] 55.297 65.9236 1.19217
154 Measured melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357] 23693.7 18263 1.29736
Ranked regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795] 249.663 298.263 1.19466
Squared t-complex protein 1, gamma subunit (tcp-1-gamma) (cct-gamma). [swissprot;acc:p49368] 42788.3 60162.6 1.40605
Rooted eukaryotic translation initiation factor 5 (eif-5). [swissprot;acc:p55010] 43.5479 51.5473 1.18369
155 Measured melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364] 23693.7 18263 1.29736
Ranked putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37] 249.663 298.263 1.19466
Squared cleavage stimulation factor, 64 kda subunit (cstf 64 kda subunit) (cf-1 64 kda subunit). [swissprot;acc:p33240] 126408 89940.5 1.40546
Rooted small nuclear ribonucleoprotein sm d2 (snrnp core protein d2) (sm-d2). [swissprot;acc:p43330] 55.7423 65.6839 1.17835
156 Measured melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] 23693.7 18263 1.29736
Ranked regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081] 249.663 298.263 1.19466
Squared septin 10 isoform 1. [refseq;acc:nm_144710] 89578.7 125883 1.40528
Rooted sh2 domain containing 3c; novel sh2-containing protein 3; sh2 domain-containing 3c; likely ortholog of mouse cas/hef1-associated signal transducer. [refseq;acc:nm_005489] 56.3447 66.124 1.17356
157 Measured hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] 23693.7 18263 1.29736
Ranked transcription factor lbx1. [swissprot;acc:p52954] 249.663 298.263 1.19466
Squared brain protein 44. [swissprot;acc:o95563] 89182.8 125229 1.40418
Rooted eukaryotic translation initiation factor 4 gamma, 3. [refseq;acc:nm_003760] 52.7582 61.9123 1.17351
158 Measured melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] 23693.7 18263 1.29736
Ranked mosaic protein lgn. [swissprot;acc:p81274] 249.663 298.263 1.19466
Squared septin 7 (cdc10 protein homolog). [swissprot;acc:q16181] 89182.8 125229 1.40418
Rooted breast cancer antiestrogen resistance 3. [refseq;acc:nm_003567] 56.3507 66.1252 1.17346
159 Measured necdin. [swissprot;acc:q99608] 23693.7 18263 1.29736
Ranked regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6] 249.663 298.263 1.19466
Squared septin 6. [swissprot;acc:q14141] 88953.6 124854 1.40359
Rooted rna-binding protein. [refseq;acc:nm_019027] 52.7642 61.9019 1.17318
160 Measured melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] 23693.7 18263 1.29736
Ranked guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471] 249.663 298.263 1.19466
Squared homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017] 173408 242989 1.40126
Rooted apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576] 52.7642 61.9019 1.17318
161 Measured melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] 23693.7 18263 1.29736
Ranked rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736] 249.663 298.263 1.19466
Squared homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483] 173408 242989 1.40126
Rooted ns1-associated protein 1. [refseq;acc:nm_006372] 52.7642 61.9019 1.17318
162 Measured melanoma antigen, family b, 6. [refseq;acc:nm_173523] 23693.7 18263 1.29736
Ranked nostrin. [refseq;acc:nm_052946] 209.299 249.187 1.19058
Squared homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444] 173408 242989 1.40126
Rooted heterogeneous nuclear ribonucleoprotein r (hnrnp r). [swissprot;acc:o43390] 52.7642 61.9019 1.17318
163 Measured melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] 23693.7 18263 1.29736
Ranked eap30 subunit of ell complex. [refseq;acc:nm_007241] 209.299 249.187 1.19058
Squared homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630] 173408 242989 1.40126
Rooted eukaryotic translation initiation factor 4 gamma (eif-4-gamma) (eif- 4g) (eif4g) (p220). [swissprot;acc:q04637] 52.7702 61.8915 1.17285
164 Measured melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] 23693.7 18263 1.29736
Ranked liv-1 protein, estrogen regulated. [refseq;acc:nm_012319] 209.299 249.187 1.19058
Squared homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016] 173408 242989 1.40126
Rooted mad protein (max dimerizer). [swissprot;acc:q05195] 55.646 65.1534 1.17086
165 Measured melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361] 23693.7 18263 1.29736

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/