Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 575 to 624 of 3730 in total
Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Rank
description
Filtered
red
green
network_comparison
288 cleavage and polyadenylation specificity factor, 73 kda subunit (cpsf 73 kda subunit). [swissprot;acc:q9ukf6] 1 23422.4 19380.3 1.20857
likely ortholog of mouse shc sh2-domain binding protein 1. [refseq;acc:nm_024745] 0 1293.73 1161.64 1.11371
289 tubby protein homolog. [swissprot;acc:p50607] 3797.57 4228.27 1.11341
u6 snrna-associated sm-like protein lsm6 (sm protein f). [swissprot;acc:q9y4y8] 1 4682.88 5646.19 1.20571
290 dna topoisomerase ii, beta isozyme (ec 5.99.1.3). [swissprot;acc:q02880] 0 1370.82 1525.56 1.11288
tuftelin-interacting protein 11 (hspc006). [swissprot;acc:q9ubb9] 1 4991.48 6014.08 1.20487
291 putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172] 44490.5 36927.5 1.20481
similar to ribosomal protein, large, p0. [sptrembl;acc:q96fq9] 0 1961.09 2179.77 1.11151
292 ba271b5.1 (similar to ribosomal protein s7). [sptrembl;acc:q9h1s9] 11223 12473 1.11138
nucleotide-binding protein 1 (nbp 1). [swissprot;acc:p53384] 1 4641.09 5588.75 1.20419
293 block 23. [sptrembl;acc:q8nhw5] 0 1943.32 2159.55 1.11127
nucleotide binding protein 2 (nbp 2). [swissprot;acc:q9y5y2] 1 4641.09 5588.75 1.20419
294 cleavage stimulation factor subunit 3; cleavage stimulation factor, 3' pre-rna, subunit 3, 77kd. [refseq;acc:nm_001326] 22515.5 18702.6 1.20387
mesoderm induction early response 1. [refseq;acc:nm_020948] 0 1914.5 1723.5 1.11082
295 adaptor-related protein complex 1, mu 2 subunit (mu-adaptin 2) (adaptor protein complex ap-1 mu-2 subunit) (golgi adaptor ha1/ap1 adaptin mu-2 subunit) (clathrin assembly protein assembly protein complex 1 medium chain 2) (ap-mu chain family member mu1b). [swissprot;acc:q9y6q5] 426.8 384.843 1.10902
ral guanine nucleotide dissociation stimulator-like 1 (ralgds-like 1). [swissprot;acc:q9nzl6] 1 13261.9 11017.8 1.20368
296 pnas-18. [sptrembl;acc:q9bzu3] 0 2256.05 2035.28 1.10847
splicing factor 3a subunit 2 (spliceosome associated protein 62) (sap 62) (sf3a66). [swissprot;acc:q15428] 1 4911.81 5909.18 1.20306
297 40s ribosomal protein s29. [swissprot;acc:p30054] 0 1711.6 1895.38 1.10737
krueppel-like factor 5 (intestinal-enriched krueppel-like factor) (colon krueppel-like factor) (transcription factor bteb2) (basic transcription element binding protein 2) (bte-binding protein 2) (gc box binding protein 2). [swissprot;acc:q13887] 1 4911.81 5909.18 1.20306
298 u6 snrna-associated sm-like protein lsm2 (small nuclear ribonuclear protein d homolog) (g7b) (snrnp core sm-like protein sm-x5). [swissprot;acc:q9y333] 4633.92 5572.85 1.20262
williams-beuren syndrome chromosome region 14 protein (ws basic-helix- loop-helix leucine zipper protein) (ws-bhlh) (mlx interactor). [swissprot;acc:q9np71] 0 939 848 1.10731
299 ba395l14.12 (novel protein similar to small nuclear ribonucleoprotein polypeptide a' (snrpa1)). [sptrembl;acc:q9nu36] 1 4914.27 5907.12 1.20203
cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551] 0 2231.05 2015.09 1.10717
300 sterol regulatory element binding protein-2 (srebp-2) (sterol regulatory element-binding transcription factor 2). [swissprot;acc:q12772] 1334.19 1205.1 1.10712
u2 small nuclear ribonucleoprotein a' (u2 snrnp-a'). [swissprot;acc:p09661] 1 4914.27 5907.12 1.20203
301 cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551] 13768.2 11466 1.20078
forkhead box protein g1c (forkhead-related protein fkhl3) (hfk3) (fragment). [swissprot;acc:q14488] 0 135.294 149.371 1.10405
302 interleukin-1 receptor-associated kinase 4; interleukin-1 receptor associated kinase 4. [refseq;acc:nm_016123]
pallidin; pallid (mouse) homolog, pallidin. [refseq;acc:nm_012388] 1 5894.75 7073.65 1.19999
303 serine/threonine protein phosphatase pp1-gamma catalytic subunit (ec 3.1.3.16) (pp-1g). [swissprot;acc:p36873] 22268.8 18560.4 1.1998
sh2 domain binding protein 1; tpr-containing, sh2-binding phosphoprotein. [refseq;acc:nm_014633] 0 952.488 863.886 1.10256
304 pre-mrna processing factor 31 homolog; pre-mrna processing factor 31 homolog (yeast). [refseq;acc:nm_015629] 1 4855.46 5824.52 1.19958
ubiquitous tropomodulin (u-tmod) (tropomodulin 3). [swissprot;acc:q9nyl9] 0 4962.34 5469.68 1.10224
305 odd-skipped related 1; odz (odd oz/ten-m) related 1. [refseq;acc:nm_145260] 1 3856.29 4624.15 1.19912
sorting nexin 9 (sh3 and px domain-containing protein 1) (sdp1 protein). [swissprot;acc:q9y5x1] 0 4962.34 5469.68 1.10224
306 glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (ec 2.6.1.16) (hexosephosphate aminotransferase 1) (d-fructose-6- phosphate amidotransferase 1) (gfat 1) (gfat1). [swissprot;acc:q06210] 1705.19 1547.2 1.10211
pnas-18. [sptrembl;acc:q9bzu3] 1 13680.5 11409.6 1.19903
307 ferritin heavy polypeptide-like 17. [swissprot;acc:q9bxu8] 0 4159.87 3775.43 1.10183
t-complex protein 1, gamma subunit (tcp-1-gamma) (cct-gamma). [swissprot;acc:p49368] 1 12365.2 14824.9 1.19892
308 neurocalcin delta. [swissprot;acc:p29554] 0 702.055 773.218 1.10136
segment polarity protein dishevelled homolog dvl-1 (dishevelled-1) (dsh homolog 1). [swissprot;acc:o14640] 1 4977.09 5966.44 1.19878
309 segment polarity protein dishevelled homolog dvl-2 (dishevelled-2) (dsh homolog 2). [swissprot;acc:o14641] 4977.8 5966.14 1.19855
suppressor of ty 5 homolog; suppressor of ty (s.cerevisiae) 5 homolog. [refseq;acc:nm_003169] 0 1890.86 2081.91 1.10104
310 purine nucleoside phosphorylase (ec 2.4.2.1) (inosine phosphorylase) (pnp). [swissprot;acc:p00491] 4755.32 4320.09 1.10075
squamous cell carcinoma antigen recognized by t cells 1; u4/u6.u5 tri-snrnp-associated 110 kda protein; ige autoantigen; sart1(259) protein; sart1(800) protein. [refseq;acc:nm_005146] 1 4909.79 5878.79 1.19736
311 segment polarity protein dishevelled homolog dvl-3 (dishevelled-3) (dsh homolog 3). [swissprot;acc:q92997] 4981.52 5964.58 1.19734
transcription factor cp2; transcription factor cp2, alpha globin. [refseq;acc:nm_005653] 0 3117.17 2833.94 1.09994
312 dyskerin (nucleolar protein nap57) (cbf5 homolog). [swissprot;acc:o60832] 3455.43 3800.29 1.0998
u6 snrna-associated sm-like protein lsm7. [swissprot;acc:q9uk45] 1 4598.21 5500.48 1.19622

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/