MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

green	description	Filtered	red	network_comparison	Value Type	Gene	Rank	Network Comparison Type	Interaction Map

Results: HTML CSV LaTeX

Showing element 1 to 32 of 32 in total

Rank  : 46

green	description	Filtered	red	network_comparison	Value Type	Network Comparison Type	Interaction Map
5.80679	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]	0	9.84765	1.69589	Rooted	Divided	Low confidence
7.48331	heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174]		12.53	1.67439			High confidence
9.07489	fos39347_1. [sptrembl;acc:o75863]		14.7546	5.67971		Subtracted	Low confidence
33.2721	hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate. [refseq;acc:nm_004712]		25.1701	8.102			High confidence
43.9629	deltex 2. [refseq;acc:nm_020892]	1	27.634	1.5909		Divided
67	ephrin type-b receptor 4 precursor (ec 2.7.1.112) (tyrosine-protein kinase receptor htk). [swissprot;acc:p54760]	0	24	2.79167	Measured		Low confidence
67.6572	atlastin; guanylate-binding protein 3. [refseq;acc:nm_015915]	1	75.6323	7.9751	Rooted	Subtracted
75.4064	jun dimerization protein. [refseq;acc:nm_130469]		66.5831	1.13252		Divided
83.274	tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702]	0	14.8562	5.60534	Squared		High confidence
98.4675	nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]		16.747	5.87971			Low confidence
120.823	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	1	137.446	16.623	Rooted	Subtracted	High confidence
161.068	fos-related antigen 1 (fra-1). [swissprot;acc:p15407]		204.642	1.27053	Ranked	Divided
217.217	protein phosphatase 1, regulatory (inhibitor) subunit 14c; serologically defined breast cancer antigen ny-br-81; pkc-potentiated pp1 inhibitory protein. [refseq;acc:nm_030949]		242.742	25.525		Subtracted	Low confidence
	protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726]			1.11751		Divided
266.948	neuralized-like. [refseq;acc:nm_004210]		332.326	65.378		Subtracted	High confidence
438.035	tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208]	0	202.163	2.16674	Measured	Divided
1390.33	neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	1	779.167	1.78438
2436.4	small glutamine rich protein with tetratricopeptide repeats 2. [refseq;acc:nm_019072]	0	3023.85	587.45		Subtracted
4196.79	putative dynein light chain protein dj8b22.1. [swissprot;acc:q9y3p0]		4607.83	411.04			Low confidence
9264.5	heat shock 70 kda protein 1 (hsp70.1) (hsp70-1/hsp70-2). [swissprot;acc:p08107]		5210.5	4054	Ranked		High confidence
9645.34	transcription regulator protein bach1 (btb and cnc homolog 1) (ha2303). [swissprot;acc:o14867]	1	8313.02	1.16027	Measured	Divided	Low confidence
12942.3	septin 7 (cdc10 protein homolog). [swissprot;acc:q16181]		11616	1326.3		Subtracted
13210.4	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]	0	17361.7	1.31424	Ranked	Divided
17020.5	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]		13825.5	3195		Subtracted
18499.2	60s ribosomal protein l37a. [swissprot;acc:p12751]		12941.7	1.42943		Divided	High confidence
20431.7	cleavage and polyadenylation specific factor 4, 30kd subunit; cleavage-polyadenylation specificity factor, 30kd; no arches-like (zebrafish) zinc finger protein; cleavage-polyadenylation specificity factor. [refseq;acc:nm_006693]	1	24896.4	4464.7	Measured	Subtracted
24837.5	folylpolyglutamate synthase, mitochondrial precursor (ec 6.3.2.17) (folylpoly-gamma-glutamate synthetase) (fpgs). [swissprot;acc:q05932]	0	30195	5357.5	Squared
35675.5	beta-tubulin 4q. [sptrembl;acc:q8wz78]		40681.2	5005.7			Low confidence
61881.5	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	1	82347.8	20466.3
	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]			1.33073		Divided
73157.5	apg3p; pc3-96 protein. [refseq;acc:nm_022488]		129597	1.77148			High confidence
136779	poly(a) polymerase alpha (ec 2.7.7.19) (pap) (polynucleotide adenylyltransferase alpha) (fragment). [swissprot;acc:p51003]		210445	73666		Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.