MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	description	Value Type	Network Comparison Type	Interaction Map	Filtered	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

Rank	description	Value Type	Network Comparison Type	green	red	network_comparison
1	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked	Subtracted	322	215	107
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Measured		33356.5	41482.5	8126
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Ranked	Divided	24	10	2.4
		Squared	Subtracted	322755	468498	145743
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Measured	Divided	2394.5	450.5	5.31521
		Squared		1357.07	48.0356	28.2513
		Rooted		48.9336	21.225	2.30547
			Subtracted			27.7086
2	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Measured		33356.5	41482.5	8126
	hbs1-like. [refseq;acc:nm_006620]	Ranked		322	215	107
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]		Divided	28	15	1.86667
		Squared	Subtracted	263351	407289	143938
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Measured	Divided	2394.5	450.5	5.31521
		Squared		1357.07	48.0356	28.2513
		Rooted		48.9336	21.225	2.30547
			Subtracted			27.7086
3	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Ranked	Divided	28	15	1.86667
		Squared	Subtracted	263351	407289	143938
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Measured		33356.5	41482.5	8126
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]		Divided	698.5	2597.5	3.71868
		Squared		115.48	1596.92	13.8285
		Rooted		26.4292	50.9657	1.92839
			Subtracted			24.5365
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Ranked		232	337	105
4	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]		Divided	28	15	1.86667
		Squared	Subtracted	263351	407289	143938
	cytohesin 4. [swissprot;acc:q9uia0]	Measured		33356.5	41482.5	8126
	hbs1-like. [refseq;acc:nm_006620]		Divided	698.5	2597.5	3.71868
		Squared		115.48	1596.92	13.8285
		Rooted		26.4292	50.9657	1.92839
			Subtracted			24.5365
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Ranked		232	337	105
5	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Rooted		168.796	145.551	23.245
	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Measured		33356.5	41482.5	8126
	cytohesin 4. [swissprot;acc:q9uia0]	Ranked	Divided	28	15	1.86667
		Squared	Subtracted	263351	407289	143938
	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	Measured	Divided	339.5	1153.5	3.39764
		Squared		27.2805	314.926	11.544
		Rooted		18.4255	33.9632	1.84327
	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]	Ranked	Subtracted	309	212	97
6	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]		Divided	28	15	1.86667
		Squared	Subtracted	263351	407289	143938
	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Measured	Divided	339.5	1153.5	3.39764
		Squared		27.2805	314.926	11.544
		Rooted		18.4255	33.9632	1.84327
	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]		Subtracted	168.796	145.551	23.245
	protein x 0004. [refseq;acc:nm_016301]	Ranked		309	212	97
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Measured		36927.5	44490.5	7563
7	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]			28492	21185	7307
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked	Divided	322	215	1.49767

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.