MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	Network Comparison Type	Gene	red	Interaction Map	Rank	network_comparison	description

Results: HTML CSV LaTeX

Showing element 551 to 600 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	Network Comparison Type	red	Interaction Map	Rank	network_comparison	description
378.206	Divided	292.152	High confidence	147	1.29455	cytochrome p450 4f11 (ec 1.14.14.1) (cypivf11). [swissprot;acc:q9hbi6]
	Subtracted			307	86.054
379.277	Divided	174.52	Low confidence	55	2.17326	selenoprotein t. [swissprot;acc:q9nzj3]
	Subtracted			275	204.757
379.474	Divided	293.178	High confidence	148	1.29435	cytochrome p450 4f8 (ec 1.14.14.1) (cypivf8). [swissprot;acc:p98187]
				149		cytochrome p450 4f2 (ec 1.14.13.30) (cypivf2) (leukotriene-b4 omega- hydroxylase) (leukotriene-b4 20-monooxygenase) (cytochrome p450- ltb-omega). [swissprot;acc:p78329]
	Subtracted			305	86.296	cytochrome p450 4f8 (ec 1.14.14.1) (cypivf8). [swissprot;acc:p98187]
				306		cytochrome p450 4f2 (ec 1.14.13.30) (cypivf2) (leukotriene-b4 omega- hydroxylase) (leukotriene-b4 20-monooxygenase) (cytochrome p450- ltb-omega). [swissprot;acc:p78329]
384.407	Divided	210.767		62	1.82385	dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743]
	Subtracted			187	173.64
384.733	Divided	470.251		186	1.22228	glycine receptor alpha-3 chain precursor. [swissprot;acc:o75311]
	Subtracted			311	85.518
384.843	Divided	426.8		295	1.10902	adaptor-related protein complex 1, mu 2 subunit (mu-adaptin 2) (adaptor protein complex ap-1 mu-2 subunit) (golgi adaptor ha1/ap1 adaptin mu-2 subunit) (clathrin assembly protein assembly protein complex 1 medium chain 2) (ap-mu chain family member mu1b). [swissprot;acc:q9y6q5]
	Subtracted			378	41.957
385.626	Divided	688.436		66	1.78524	soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825]
			Low confidence	73
	Subtracted		High confidence	104	302.81
			Low confidence	194
391	Divided	294		128	1.32993	double-stranded rna-specific editase 1 (ec 3.5.-.-) (dsrna adenosine deaminase) (rna editing deaminase 1) (rna editing enzyme 1). [swissprot;acc:p78563]
	Subtracted			443	97
399.534	Divided	348.823	High confidence	233	1.14538	maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168]
	Subtracted			360	50.711
402	Divided	594		100	1.47761	atp-dependent dna helicase ii, 70 kda subunit (lupus ku autoantigen protein p70) (ku70) (70 kda subunit of ku antigen) (thyroid-lupus autoantigen) (tlaa) (ctc box binding factor 75 kda subunit) (ctcbf) (ctc75). [swissprot;acc:p12956]
	Subtracted			171	192
402.138	Divided	380.866	Low confidence	520	1.05585	dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743]
	Subtracted			735	21.272
403.196	Divided	870.482	High confidence	48	2.15895	deltex homolog 1; hdx-1. [refseq;acc:nm_004416]
	Subtracted			61	467.286
405.367	Divided	387.486		385	1.04615	40s ribosomal protein s28. [swissprot;acc:p25112]
	Subtracted			430	17.881
410	Divided	556	Low confidence	115	1.3561	g protein-coupled receptor kinase grk5 (ec 2.7.1.-) (g-protein-coupled receptor kinase 5). [swissprot;acc:p34947]
				116		g protein-coupled receptor kinase grk6 (ec 2.7.1.-) (g-protein-coupled receptor kinase 6). [swissprot;acc:p43250]
	Subtracted			335	146	g protein-coupled receptor kinase grk5 (ec 2.7.1.-) (g-protein-coupled receptor kinase 5). [swissprot;acc:p34947]
				336		g protein-coupled receptor kinase grk6 (ec 2.7.1.-) (g-protein-coupled receptor kinase 6). [swissprot;acc:p43250]
416.524	Divided	712.071	High confidence	77	1.70956	inosine-5'-monophosphate dehydrogenase 2 (ec 1.1.1.205) (imp dehydrogenase 2) (impdh-ii) (impd 2). [swissprot;acc:p12268]
	Subtracted			106	295.547
417.983	Divided	331.61		167	1.26047	transcription factor mafk (erythroid transcription factor nf-e2 p18 subunit). [swissprot;acc:o60675]
	Subtracted			303	86.373
420.355	Divided	334.012		168	1.2585	transcription factor mafg (v-maf musculoaponeurotic fibrosarcoma oncogene homolog g) (hmaf). [swissprot;acc:o15525]
	Subtracted			304	86.343
421	Divided	292		108	1.44178	basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811]
	Subtracted			245	129
426.641	Divided	374.834	Low confidence	340	1.13821	syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623]
	Subtracted			596	51.807
429	Divided	426	High confidence	477	1.00704	atlastin; guanylate-binding protein 3. [refseq;acc:nm_015915]
			Low confidence	791
	Subtracted		High confidence	479	3
			Low confidence	811
430.121	Divided	553.827		145	1.28761	lipocalin-interacting membrane receptor. [refseq;acc:nm_018113]
	Subtracted			390	123.706

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.