Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type Gene Filtered green Interaction Map Rank red description Network Comparison Type network_comparison
Results: HTML CSV LaTeX Showing element 51 to 100 of 29840 in total
Value Type  : Measured
Filtered  : 0
Interaction Map  : High confidence
green
Rank
red
description
Network Comparison Type
network_comparison
21 50 44 transcription factor 4 (immunoglobulin transcription factor 2) (itf-2) (sl3-3 enhancer factor 2) (sef-2). [swissprot;acc:p15884] Divided 2.09524
407 Subtracted 23
26.1599 18 305.45 60s ribosomal protein l37a. [swissprot;acc:p12751] Divided 11.6763
19 25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]
114 60s ribosomal protein l37a. [swissprot;acc:p12751] Subtracted 279.29
115 25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]
37.4843 89 23.6076 suppressor of actin 1. [refseq;acc:nm_014016] Divided 1.58781
446 Subtracted 13.8767
37.693 73 65.2968 protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236] Divided 1.73233
400 Subtracted 27.6038
39.8063 33 12.6208 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [refseq;acc:nm_003893] Divided 3.15402
402 Subtracted 27.1855
43 7 0.00001 sedlin. [swissprot;acc:o14582] Divided 4300000
8 synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
118 31 methyltransferase like 2. [refseq;acc:nm_018396] 1.3871
376 0 sedlin. [swissprot;acc:o14582] Subtracted 43
377 synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
450 31 methyltransferase like 2. [refseq;acc:nm_018396] 12
47 13 1363 adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61] Divided 29
Subtracted 1316
34 143 glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] Divided 3.04255
277 Subtracted 96
50 81 30 transcription initiation factor iie, beta subunit (tfiie-beta). [swissprot;acc:p29084] Divided 1.66667
426 Subtracted 20
51 350 48 melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] Divided 1.0625
351 melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]
352 melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]
353 melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
354 hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]
355 melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
356 melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]
357 melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]
358 melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]
359 melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]
360 melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]
361 melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]
362 melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]
363 melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]
364 melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]
365 melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]
366 melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]
467 melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] Subtracted 3
468 melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]
469 melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]
470 melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
471 hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]
472 melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
473 melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]
474 melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]
475 melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/