Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 25824 in total

Interaction Map	High confidence
Filtered	1

Rank	description	Value Type	Network Comparison Type	red	green	network_comparison	
7	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [source:refseq;acc:nm_006333]	Squared	Subtracted	310840	442993	132153	
7	pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [source:swissprot;acc:q9bz23]	Rooted	Subtracted	145.551	168.796	23.245	
7	protein cgi-126 (protein hspc155). [source:swissprot;acc:q9y3c8]	Ranked	Subtracted	288.754	212.554	76.2	
7	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Measured	Divided	1153.5	339.5	3.39764	
7	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Squared	Divided	314.926	27.2805	11.544	
7	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Rooted	Divided	33.9632	18.4255	1.84327	
8	db83 protein. [source:swissprot;acc:p57088]	Measured	Divided	1153.5	339.5	3.39764	
8	db83 protein. [source:swissprot;acc:p57088]	Squared	Divided	314.926	27.2805	11.544	
8	db83 protein. [source:swissprot;acc:p57088]	Rooted	Divided	33.9632	18.4255	1.84327	
8	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [source:refseq;acc:nm_021233]	Squared	Subtracted	250303	354894	104591	
8	hbs1-like. [source:refseq;acc:nm_006620]	Ranked	Divided	215	322	1.49767	
8	junctophilin 3 (junctophilin type 3) (jp-3). [source:swissprot;acc:q8wxh2]	Ranked	Subtracted	288	362	74	
8	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [source:swissprot;acc:q8te04]	Measured	Subtracted	21185	28492	7307	
8	pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [source:swissprot;acc:q9h999]	Rooted	Subtracted	145.551	168.796	23.245	
9	junctophilin 2 (junctophilin type 2) (jp-2). [source:swissprot;acc:q9br39]	Ranked	Subtracted	288	362	74	
9	mitochondrial solute carrier protein. [source:refseq;acc:nm_145305]	Rooted	Subtracted	145.551	168.796	23.245	
9	pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [source:swissprot;acc:q9bz23]	Measured	Subtracted	21185	28492	7307	
9	protein phosphatase 1, regulatory subunit 7; sds22. [source:refseq;acc:nm_002712]	Squared	Subtracted	256169	162517	93652	
9	tob2 protein (transducer of erbb-2 2). [source:swissprot;acc:q14106]	Measured	Divided	398.5	1281.5	3.21581	
9	tob2 protein (transducer of erbb-2 2). [source:swissprot;acc:q14106]	Squared	Divided	37.5863	388.696	10.3414	
9	tob2 protein (transducer of erbb-2 2). [source:swissprot;acc:q14106]	Rooted	Divided	19.9625	35.798	1.79326	
9	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [source:refseq;acc:nm_007266]	Ranked	Divided	212	309	1.45755	
10	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [source:refseq;acc:nm_030801]	Squared	Subtracted	219048	129762	89286	
10	pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [source:swissprot;acc:q9h999]	Measured	Subtracted	21185	28492	7307	
10	protein x 0004. [source:refseq;acc:nm_016301]	Ranked	Divided	212	309	1.45755	
10	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [source:swissprot;acc:o60906]	Ranked	Subtracted	288	362	74	
10	tob1 protein (transducer of erbb-2 1). [source:swissprot;acc:p50616]	Measured	Divided	398.5	1281.5	3.21581	
10	tob1 protein (transducer of erbb-2 1). [source:swissprot;acc:p50616]	Squared	Divided	37.5863	388.696	10.3414	
10	tob1 protein (transducer of erbb-2 1). [source:swissprot;acc:p50616]	Rooted	Divided	19.9625	35.798	1.79326	
10	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [source:refseq;acc:nm_007266]	Rooted	Subtracted	51.6817	29.5127	22.169	
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Measured	Divided	398.5	1281.5	3.21581	
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Squared	Divided	37.5863	388.696	10.3414	
11	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [source:refseq;acc:nm_032552]	Rooted	Divided	19.9625	35.798	1.79326	
11	db83 protein. [source:swissprot;acc:p57088]	Ranked	Subtracted	288	362	74	
11	hepatocellular carcinoma-associated protein hca3. [source:refseq;acc:nm_138703]	Squared	Subtracted	219048	129762	89286	
11	mitochondrial solute carrier protein. [source:refseq;acc:nm_145305]	Measured	Subtracted	21185	28492	7307	
11	protein x 0004. [source:refseq;acc:nm_016301]	Rooted	Subtracted	51.6817	29.5127	22.169	
11	rad50-interacting protein 1. [source:refseq;acc:nm_021930]	Ranked	Divided	337	232	1.45259	
12	beta-arrestin 2 (arrestin, beta 2). [source:swissprot;acc:p32121]	Rooted	Subtracted	80.4705	101.526	21.0555	
12	cytoplasmic polyadenylation element binding protein 4. [source:refseq;acc:nm_030627]	Measured	Divided	398.5	1281.5	3.21581	
12	cytoplasmic polyadenylation element binding protein 4. [source:refseq;acc:nm_030627]	Squared	Divided	37.5863	388.696	10.3414	
12	cytoplasmic polyadenylation element binding protein 4. [source:refseq;acc:nm_030627]	Rooted	Divided	19.9625	35.798	1.79326	
12	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-7 subunit. [source:swissprot;acc:o60262]	Ranked	Subtracted	266.856	336.233	69.377	
12	melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [source:swissprot;acc:p43357]	Squared	Subtracted	219048	129762	89286	
12	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [source:refseq;acc:nm_006333]	Measured	Subtracted	34190.9	40795.8	6604.9	
12	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [source:swissprot;acc:q9byz6]	Ranked	Divided	337	232	1.45259	
13	beta-arrestin 1 (arrestin, beta 1). [source:swissprot;acc:p49407]	Rooted	Subtracted	80.4705	101.526	21.0555	
13	cytoplasmic polyadenylation element binding protein 3. [source:refseq;acc:nm_014912]	Measured	Divided	398.5	1281.5	3.21581	
13	cytoplasmic polyadenylation element binding protein 3. [source:refseq;acc:nm_014912]	Squared	Divided	37.5863	388.696	10.3414	
13	cytoplasmic polyadenylation element binding protein 3. [source:refseq;acc:nm_014912]	Rooted	Divided	19.9625	35.798	1.79326	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/