Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1151 to 1200 of 6456 in total
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1
Rank
description
Network Comparison Type
red
green
network_comparison
576 45 kda calcium-binding protein precursor (cab45) (stromal cell-derived factor 4) (sdf-4). [swissprot;acc:q9brk5] Subtracted 7813.48 8570.11 756.63
homeobox protein hox-c9 (hox-3b). [swissprot;acc:p31274] Divided 6739.7 7644.6 1.13426
577 band 4.1-like protein 3 (4.1b) (differentially expressed in adenocarcinoma of the lung protein 1) (dal-1). [swissprot;acc:q9y2j2] Subtracted 7813.45 8570.07 756.62
gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928] Divided 6739.81 7644.62 1.13425
578 forkhead box protein g1c (forkhead-related protein fkhl3) (hfk3) (fragment). [swissprot;acc:q14488]
protein 4.1 (band 4.1) (p4.1) (epb4.1) (4.1r). [swissprot;acc:p11171] Subtracted 7813.35 8569.96 756.61
579 band 4.1-like protein 1 (neuronal protein 4.1) (4.1n). [swissprot;acc:q9h4g0] 7813.34 8569.95
gamma-aminobutyric-acid receptor gamma-1 subunit precursor (gaba(a) receptor). [swissprot;acc:q8n1c3] Divided 6739.82 7644.62 1.13425
580 band 4.1-like protein 2 (generally expressed protein 4.1) (4.1g). [swissprot;acc:o43491] Subtracted 7813.36 8569.97 756.61
gamma-aminobutyric-acid receptor alpha-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p47869] Divided 6739.83 7644.63 1.13425
581 galectin-9 (hom-hd-21) (ecalectin). [swissprot;acc:o00182] Subtracted 7810.11 8566.29 756.18
gamma-aminobutyric-acid receptor alpha-6 subunit precursor (gaba(a) receptor). [swissprot;acc:q16445] Divided 6739.82 7644.63 1.13425
582 gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507] 7644.62
nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7] Subtracted 6834.54 7590.49 755.95
583 importin beta-1 subunit (karyopherin beta-1 subunit) (nuclear factor p97) (importin 90). [swissprot;acc:q14974]
interleukin-1 receptor-associated kinase 4; interleukin-1 receptor associated kinase 4. [refseq;acc:nm_016123] Divided 6739.81 7644.62 1.13425
584 gamma-aminobutyric-acid receptor alpha-4 subunit precursor (gaba(a) receptor). [swissprot;acc:p48169] 6739.82 7644.63
transducin beta-like 1x protein (transducin-beta-like 1, x-linked). [swissprot;acc:o60907] Subtracted 6834.54 7590.49 755.95
585 gamma-aminobutyric-acid receptor epsilon subunit precursor (gaba(a) receptor). [swissprot;acc:p78334] Divided 6739.82 7644.63 1.13425
transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87] Subtracted 6834.54 7590.49 755.95
586 apolipoprotein a-i binding protein; apoa-i binding protein. [refseq;acc:nm_144772] 6139.04 6893.7 754.66
phosphatidylserine receptor; phosphatidylserine receptor beta. [refseq;acc:nm_015167] Divided 6739.81 7644.62 1.13425
587 axonemal dynein light intermediate polypeptide 1 (inner dynein arm light chain, axonemal) (hp28). [swissprot;acc:o14645] Subtracted 6772.75 7526.2 753.45
gamma-aminobutyric-acid receptor alpha-1 subunit precursor (gaba(a) receptor). [swissprot;acc:p14867] Divided 6739.83 7644.63 1.13425
588 gamma-aminobutyric-acid receptor alpha-3 subunit precursor (gaba(a) receptor). [swissprot;acc:p34903]
ubiquitin-conjugating enzyme e2 variant 1 isoform b; dna-binding protein. [refseq;acc:nm_003349] Subtracted 6691.93 7445.09 753.16
589 nadh-ubiquinone oxidoreductase b14 subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b14) (ci-b14). [swissprot;acc:p56556] Divided 6739.85 7644.63 1.13424
utp--glucose-1-phosphate uridylyltransferase 2 (ec 2.7.7.9) (udp- glucose pyrophosphorylase 2) (udpgp 2) (ugpase 2). [swissprot;acc:q16851] Subtracted 6691.21 7444.22 753.01
590 similar to expressed sequence aa415817. [sptrembl;acc:q8n4q9] Divided 6739.85 7644.63 1.13424
ubiquitin-conjugating enzyme e2 variant 2; 1 alpha,25-dihydroxyvitamin d3-inducible; enterocyte differentiation promoting factor; methyl methanesulfonate sensitive 2, s. cerevisiae, homolog of. [refseq;acc:nm_003350] Subtracted 6690.44 7443.29 752.85
591 homeobox protein hox-d9 (hox-4c) (hox-5.2). [swissprot;acc:p28356] Divided 6740.5 7644.76 1.13415
u4/u6-associated rna splicing factor. [refseq;acc:nm_004698] Subtracted 5390.78 6142.07 751.29
592 arginyl-trna synthetase-like; arginine-trna ligase. [refseq;acc:nm_020320] 7093.86 7842.67 748.81
histone h2b.c (h2b/c). [swissprot;acc:q99880] Divided 3946.32 4475.47 1.13409
593 histone h2b.q (h2b/q) (h2b-gl105). [swissprot;acc:q16778]
nadh-ubiquinone oxidoreductase b22 subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b22) (ci-b22). [swissprot;acc:q9y6m9] Subtracted 6770.78 7517.97 747.19
594 histone h3.1 (h3/a) (h3/c) (h3/d) (h3/f) (h3/h) (h3/i) (h3/j) (h3/k) (h3/l). [swissprot;acc:p16106] Divided 3946.32 4475.47 1.13409
shroom-related protein; f-actin-binding protein; likely ortholog of mouse shroom. [refseq;acc:nm_020859] Subtracted 6089.21 6835.34 746.13
595 apical-like protein (apxl protein). [swissprot;acc:q13796] 6088.77 6834.87 746.1
histone h2b. [refseq;acc:nm_175055] Divided 3946.32 4475.47 1.13409
596 histone h2b.s (h2b/s). [swissprot;acc:p57053]
parkinson disease (autosomal recessive, juvenile) 2, parkin isoform 1; parkin. [refseq;acc:nm_004562] Subtracted 4533.74 5279.4 745.66
597 hepatoma-derived growth factor-related protein 2. [refseq;acc:nm_032631]
histone h2b.d (h2b/d). [swissprot;acc:q99877] Divided 3946.32 4475.47 1.13409
598 cgi-142; hepatoma-derived growth factor 2. [refseq;acc:nm_016073] Subtracted 4533.74 5279.4 745.66
histone h3.4 (h3t) (h3/t) (h3/g). [swissprot;acc:q16695] Divided 3946.32 4475.47 1.13409
599 pc4 and sfrs1 interacting protein 2; pc4 and sfrs1 interacting protein 1; transcriptional coactivator p52/p75. [refseq;acc:nm_033222] Subtracted 4533.74 5279.4 745.66
testis-specific histone h2b; h2b histone family, member u, (testis-specific). [refseq;acc:nm_170610] Divided 3946.32 4475.47 1.13409
600 60s ribosomal protein l8. [swissprot;acc:p25120] Subtracted 4533.74 5279.4 745.66
histone h2b.e (h2b/e). [swissprot;acc:q99879] Divided 3946.32 4475.47 1.13409

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/